NSC 55712

Product Name: NSC 55712
CAS No.: 2076-91-7
Chemical Name: NSC 55712
Synonyms: R 55;NSC 55712;TPT-260 2HCl;TPT-260 , NSC55712;TPT-260 2HCl (R55);TPT-260 2HCl(NSC55712);TPT-260 (hydrochloride);TPU-260 Dihydrochloride;NSC55712 Dihydrochloride;TPT-260 (Dihydrochloride)
CBNumber: CB02667773
Molecular Formula: C8H14Cl2N4S3
Formula Weight: 333.32456
MOL File: 2076-91-7.mol

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NSC 55712 Property

Melting point:: 210℃ (Decomposition)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO:62.5(Max Conc. mg/mL);240.02(Max Conc. mM)
form: A crystalline solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16079
Product name: TPT-260 (hydrochloride)
Purity: ≥95%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 16079
Product name: TPT-260 (hydrochloride)
Purity: ≥95%
Packaging: 5mg
Price: $140
Updated: 2024/03/01

Cayman Chemical

Product number: 16079
Product name: TPT-260 (hydrochloride)
Purity: ≥95%
Packaging: 10mg
Price: $235
Updated: 2024/03/01

Cayman Chemical

Product number: 16079
Product name: TPT-260 (hydrochloride)
Purity: ≥95%
Packaging: 25mg
Price: $479
Updated: 2024/03/01

AK Scientific

Product number: SYN5349
Product name: R55
Packaging: 50mg
Price: $757
Updated: 2021/12/16

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NSC 55712 Chemical Properties,Usage,Production

Uses

Retromers are multiprotein complexes responsible for trafficking cargo out of endosomes. This is an important function that, in the case of amyloid-precursor protein (APP), is neuroprotective by preventing APP from being cleaved into Alzheimer’s disease-inducing fragments via the endosome. TPT-260 is a thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~5 μM). In cultured hippocampal neurons, TPT-260 dose-dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of pathogenic APP.[Cayman Chemical]

NSC 55712 Preparation Products And Raw materials

Raw materials

Preparation Products

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NSC 55712 Suppliers

China 41 India 1 The Netherlands 1 United States 12 Global 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4153
Advantage: 55

D&C Chemicals

Tel: +86-21-58447131
Fax: +86-21-61642470
Email: 1724405207@qq.com
Country: China
ProdList: 472
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9254
Advantage: 55

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9638
Advantage: 58

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3868
Advantage: 58

2076-91-7, NSC 55712Related Search:

NSC 55712

TPT-260 (Dihydrochloride)

THIOPHENE-2,5-DIYLBIS(METHYLENE) DICARBAMIMIDOTHIOATE.2HCL

TPT-260 (Dihydrochloride), NSC55712

TPT-260 2HCl

Carbamimidothioic acid 2,5-thiophenediylbis(methylene) ester dihydrochloride

Carbamimidothioic acid,C,C'-[2,5-thiophenediylbis(methylene)] ester, hydrochloride (1:2)

TPT-260 , NSC55712

NSC 55712 Carbamimidothioic acid 2,5-thiophenediylbis(methylene) ester dihydrochloride

TPT-260 Dihydrochloride, >=98%

Thiophene-2,5-diylbis(methylene) dicarbamimidothioate dihydrochloride

NSC55712 Dihydrochloride

TPT-260 2HCl(NSC55712)

R 55

TPT-260 (hydrochloride)

thiene-2,5-diyldimethanediyl dicarbamimidothioate

NSC55712; TPT260 DIHYDROCHLORIDE; TPT 260 DIHYDROCHLORIDE; TPU-260 DIHYDROCHLORIDE;NSC-55712;NSC 55712

TPU-260 Dihydrochloride

[({5-[(carbamimidoylsulfanyl)methyl]thiophen-2-yl}methyl)sulfanyl]methanimidamide dihydrochloride

TPT-260 2HCl (R55)

TPT 260 Dihydrochloride,Inhibitor,inhibit,TPU 260,TPU260,TPT260 Dihydrochloride,NSC 55712,TPU-260,NSC-55712

2076-91-7

C8H12N4S32HCl

C8H14Cl2N4S3

C8H12N4S32ClH

Inhibitors