NSC 55712

Product Name: NSC 55712
CAS No.: 2076-91-7
Chemical Name: NSC 55712
Synonyms: R 55;NSC 55712;TPT-260 2HCl;TPT-260 , NSC55712;TPT-260 2HCl (R55);TPT-260 2HCl(NSC55712);TPT-260 (hydrochloride);TPU-260 Dihydrochloride;NSC55712 Dihydrochloride;TPT-260 (Dihydrochloride)
CBNumber: CB02667773
Molecular Formula: C8H14Cl2N4S3
Formula Weight: 333.32456
MOL File: 2076-91-7.mol

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NSC 55712 Property

Melting point:: 210℃ (Decomposition)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO:62.5(Max Conc. mg/mL);240.02(Max Conc. mM)
form: A crystalline solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16079
Product name: TPT-260 (hydrochloride)
Purity: ≥95%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 16079
Product name: TPT-260 (hydrochloride)
Purity: ≥95%
Packaging: 5mg
Price: $140
Updated: 2024/03/01

Cayman Chemical

Product number: 16079
Product name: TPT-260 (hydrochloride)
Purity: ≥95%
Packaging: 10mg
Price: $235
Updated: 2024/03/01

Cayman Chemical

Product number: 16079
Product name: TPT-260 (hydrochloride)
Purity: ≥95%
Packaging: 25mg
Price: $479
Updated: 2024/03/01

AK Scientific

Product number: SYN5349
Product name: R55
Packaging: 10mg
Price: $217
Updated: 2021/12/16

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NSC 55712 Chemical Properties,Usage,Production

Uses

Retromers are multiprotein complexes responsible for trafficking cargo out of endosomes. This is an important function that, in the case of amyloid-precursor protein (APP), is neuroprotective by preventing APP from being cleaved into Alzheimer’s disease-inducing fragments via the endosome. TPT-260 is a thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~5 μM). In cultured hippocampal neurons, TPT-260 dose-dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of pathogenic APP.[Cayman Chemical]

NSC 55712 Preparation Products And Raw materials

Raw materials

Preparation Products

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NSC 55712 Suppliers

China 45 India 1 The Netherlands 1 United States 12 Global 59

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4512
Advantage: 55

D&C Chemicals

Tel: +86-21-58447131
Fax: +86-21-61642470
Email: 1724405207@qq.com
Country: China
ProdList: 472
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

2076-91-7, NSC 55712Related Search:

NSC 55712

TPT-260 (Dihydrochloride)

THIOPHENE-2,5-DIYLBIS(METHYLENE) DICARBAMIMIDOTHIOATE.2HCL

TPT-260 (Dihydrochloride), NSC55712

TPT-260 2HCl

Carbamimidothioic acid 2,5-thiophenediylbis(methylene) ester dihydrochloride

Carbamimidothioic acid,C,C'-[2,5-thiophenediylbis(methylene)] ester, hydrochloride (1:2)

TPT-260 , NSC55712

NSC 55712 Carbamimidothioic acid 2,5-thiophenediylbis(methylene) ester dihydrochloride

TPT-260 Dihydrochloride, >=98%

Thiophene-2,5-diylbis(methylene) dicarbamimidothioate dihydrochloride

NSC55712 Dihydrochloride

TPT-260 2HCl(NSC55712)

R 55

TPT-260 (hydrochloride)

thiene-2,5-diyldimethanediyl dicarbamimidothioate

NSC55712; TPT260 DIHYDROCHLORIDE; TPT 260 DIHYDROCHLORIDE; TPU-260 DIHYDROCHLORIDE;NSC-55712;NSC 55712

TPU-260 Dihydrochloride

[({5-[(carbamimidoylsulfanyl)methyl]thiophen-2-yl}methyl)sulfanyl]methanimidamide dihydrochloride

TPT-260 2HCl (R55)

TPT 260 Dihydrochloride,Inhibitor,inhibit,TPU 260,TPU260,TPT260 Dihydrochloride,NSC 55712,TPU-260,NSC-55712

Carbamimidothioic acid, C,C'-[2,5-thiophenediylbis(methylene)] ester, hydrochloride (1:2)

2076-91-7

C8H12N4S32HCl

C8H14Cl2N4S3

C8H12N4S32ClH

Inhibitors