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Doxycycline Hyclate IMpurity F

Product Name
Doxycycline Hyclate IMpurity F
CAS No.
122861-53-4
Chemical Name
Doxycycline Hyclate IMpurity F
Synonyms
Doxycycline Impurity 2;Doxycycline Hyclate IMpurity F;2-Acetyl-2-decarbamoyldoxycycline;Doxycycline Impurity 6(Doxycycline EP Impurity F);(4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino);(1S,4aR,11R,11aR,12S,12aR)-3-acetyl-1-(dimethylamino)-4,4a,6,7,12-pentahydroxy-11-methyl-11,11a,12,12a-tetrahydro-1H-tetracene-2,5-dione;(4S)-4beta-Dimethylamino-1,4,4abeta,5,5abeta,6,11,12a-octahydro-3,5beta,10,12,12abeta-pentahydroxy-6beta-methyl-1,11-dioxo-2-acetylnaphthacene;1,11(4H,5H)-Naphthacenedione, 2-acetyl-4-(dimethylamino)-4a,5a,6,12a-tetrahydro-3,5,10,12,12a-pentahydroxy-6-methyl-, (4S,4aR,5S,5aR,6R,12aS)-;(4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-4a,5,5a,6-tetrahydrotetracene-1,11(4H,12aH)-dione? (Doxycycline Impurity);(4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,11(4H,5H)-dione (2-acetyl-2-decarbamoyldoxycycline).
CBNumber
CB02674144
Molecular Formula
C23H25NO8
Formula Weight
443.45
MOL File
122861-53-4.mol
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Doxycycline Hyclate IMpurity F Property

Boiling point:
711.0±60.0 °C(Predicted)
Density 
1.56±0.1 g/cm3(Predicted)
pka
4.50±1.00(Predicted)
InChIKey
MVCRKRBIKNEKEE-ACDFWTBPSA-N
SMILES
C1(=O)[C@]2(O)[C@@]([H])([C@@H](O)[C@@]3([H])C(=C2O)C(=O)C2=C(C=CC=C2O)[C@@H]3C)[C@H](N(C)C)C(O)=C1C(C)=O
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Hazard and Precautionary Statements (GHS)

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Doxycycline Hyclate IMpurity F Chemical Properties,Usage,Production

Description

2-acetyl-2-decarbamoyl-doxycycline, also known as Doxycycline Hyclate IMpurity F, is an impurity of Doxycycline. Doxycycline hyclate is an antibacterial drug synthetically derived from oxytetracycline and is available as doxycycline hyclate capsules for oral administration. To reduce the development of drug-resistant bacteria and maintain the effectiveness of doxycycline hyclate and other antibacterial drugs, doxycycline hyclate capsules should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

Doxycycline Hyclate IMpurity F Preparation Products And Raw materials

Raw materials

Preparation Products

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122861-53-4, Doxycycline Hyclate IMpurity FRelated Search:


  • Doxycycline Hyclate IMpurity F
  • Doxycycline Impurity 6(Doxycycline EP Impurity F)
  • (1S,4aR,11R,11aR,12S,12aR)-3-acetyl-1-(dimethylamino)-4,4a,6,7,12-pentahydroxy-11-methyl-11,11a,12,12a-tetrahydro-1H-tetracene-2,5-dione
  • (4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)
  • 1,11(4H,5H)-Naphthacenedione, 2-acetyl-4-(dimethylamino)-4a,5a,6,12a-tetrahydro-3,5,10,12,12a-pentahydroxy-6-methyl-, (4S,4aR,5S,5aR,6R,12aS)-
  • (4S)-4beta-Dimethylamino-1,4,4abeta,5,5abeta,6,11,12a-octahydro-3,5beta,10,12,12abeta-pentahydroxy-6beta-methyl-1,11-dioxo-2-acetylnaphthacene
  • 2-Acetyl-2-decarbamoyldoxycycline
  • (4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,11(4H,5H)-dione (2-acetyl-2-decarbamoyldoxycycline).
  • Doxycycline Impurity 2
  • (4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-4a,5,5a,6-tetrahydrotetracene-1,11(4H,12aH)-dione? (Doxycycline Impurity)
  • 122861-53-4