ChemicalBook > CAS DataBase List > Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
- Product Name
- Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
- CAS No.
- 1132709-16-0
- Chemical Name
- Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
- Synonyms
- Bortizomib SR-OH;(1S,2R)-BortezoMib;Bortezomib (1R,2R)Isomer;Bortezomib S,R Enantiomer;Bortezomib (1S, 2R)-Isomer;(1S,2R)-Bortezomib Impurity;Bortezomib S,R-Isomer Impurity;Bortezomib impurities (R, S-isomer);Bortezomib Impurity (1S,2R - Isomer);Bortezomib impurity 2/(1S,2R)-Bortezomib
- CBNumber
- CB02677165
- Molecular Formula
- C19H25BN4O4
- Formula Weight
- 384.24
- MOL File
- 1132709-16-0.mol
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Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Property
- Density
- 1.214±0.06 g/cm3(Predicted)
- solubility
- Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
- pka
- 9.66±0.43(Predicted)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic, Light sensitive, Moisture sensitive
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N-Bromosuccinimide Price
TRC
- Product number
- B675710
- Product name
- (1S,2R)-Bortezomib
- Packaging
- 50mg
- Price
- $375
- Updated
- 2021/12/16
Chemenu
- Product number
- CM205039
- Product name
- ((S)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
- Purity
- 95%+
- Packaging
- 100mg
- Price
- $668
- Updated
- 2021/12/16
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Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Chemical Properties,Usage,Production
Uses
(1S,3R)-Bortezomib is an diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
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Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Suppliers
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1132709-16-0, Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-Related Search:
2-PyrazinecarboxaMide, N,N',N''-[2,4,6-boroxintriyltris[[(1R)-3-Methylbutylidene]iMino[(1S)-2-oxo-1-(phenylMethyl)-2,1-ethanediyl]]]tris-
BORTEZOMIB-PINANEDIOL
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
Bortezomib Impurity 2 (Mixture of (1S,2R)-Isomer and (1R,2R)-Isomer)
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
Bortezomib Impurity 1 (R,S-Isomer)
BortezoMib IMpurity 2 (RR-IsoMer)
(S)-N-(1-(3-MethylbutanaMido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
bortezoMib iMpurity H
Bortezomib
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid