ChemicalBook > CAS DataBase List > Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-

Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-

Product Name
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
CAS No.
1132709-16-0
Chemical Name
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
Synonyms
Bortizomib SR-OH;(1S,2R)-BortezoMib;Bortezomib (1R,2R)Isomer;Bortezomib S,R Enantiomer;Bortezomib (1S, 2R)-Isomer;(1S,2R)-Bortezomib Impurity;Bortezomib S,R-Isomer Impurity;Bortezomib impurities (R, S-isomer);Bortezomib Impurity (1S,2R - Isomer);Bortezomib impurity 2/(1S,2R)-Bortezomib
CBNumber
CB02677165
Molecular Formula
C19H25BN4O4
Formula Weight
384.24
MOL File
1132709-16-0.mol
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Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Property

Density 
1.214±0.06 g/cm3(Predicted)
solubility 
Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
9.66±0.43(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic, Light sensitive, Moisture sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B675710
Product name
(1S,2R)-Bortezomib
Packaging
50mg
Price
$375
Updated
2021/12/16
Chemenu
Product number
CM205039
Product name
((S)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
Purity
95%+
Packaging
100mg
Price
$668
Updated
2021/12/16
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Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Chemical Properties,Usage,Production

Uses

(1S,3R)-Bortezomib is an diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway

Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Jiangsu Vcare PharmaTech Co., Ltd.
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025-58741518; 18013018875
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+86-25-58744115
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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0755-4000505016 13380397412
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0755 28094224
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Beijing Comparison Pharmaceutical Technology Co., Ltd
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010-010-52878169 15801002657
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Shanghai potentpharm CO.,Ltd
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(86) 21 51969655, QQ: 263541193
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ChemStrong Scientific Co.,Ltd
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Tianjin Anhao Biological Technology Co., Ltd.
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Shanghai Synteam Biochem CO.,ltd
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1132709-16-0, Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-Related Search:


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  • Bortezomib Impurity (1S,2R - Isomer)
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  • Bortezomib (1R,2R)Isomer
  • (1S,2R)-Bortezomib Impurity
  • Bortezomib impurities (R, S-isomer)
  • Bortezomib (1S, 2R)-Isomer
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