ChemicalBook > CAS DataBase List > 2-(BOC-aMino)-3-hydroxypyridine

2-(BOC-aMino)-3-hydroxypyridine

Product Name
2-(BOC-aMino)-3-hydroxypyridine
CAS No.
902835-93-2
Chemical Name
2-(BOC-aMino)-3-hydroxypyridine
Synonyms
2-(BOC-aMino)-3-hydroxypyridine;tert-Butyl (3-hydroxypyridin-2-yl)carbamate;N-(3-Hydroxy-2-pyridinyl)carbamic acid 1,1-dimethylethyl ester;Carbamic acid, N-(3-hydroxy-2-pyridinyl)-, 1,1-dimethylethyl ester
CBNumber
CB02686570
Molecular Formula
C10H14N2O3
Formula Weight
210.23
MOL File
902835-93-2.mol
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2-(BOC-aMino)-3-hydroxypyridine Property

Melting point:
129-132℃
Boiling point:
337.5±27.0 °C(Predicted)
Density 
1.235±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
8.80±0.10(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B663308
Product name
2-(Boc-Amino)-3-hydroxypyridine
Packaging
500mg
Price
$175
Updated
2021/12/16
AK Scientific
Product number
9735AL
Product name
2-Methyl-2-propanyl(3-hydroxy-2-pyridinyl)carbamate
Packaging
1g
Price
$100
Updated
2021/12/16
Ambeed
Product number
A217578
Product name
tert-Butyl(3-hydroxypyridin-2-yl)carbamate
Purity
97%
Packaging
250mg
Price
$6
Updated
2021/12/16
Ambeed
Product number
A217578
Product name
tert-Butyl(3-hydroxypyridin-2-yl)carbamate
Purity
97%
Packaging
1g
Price
$9
Updated
2021/12/16
Ambeed
Product number
A217578
Product name
tert-Butyl(3-hydroxypyridin-2-yl)carbamate
Purity
97%
Packaging
5g
Price
$32
Updated
2021/12/16
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2-(BOC-aMino)-3-hydroxypyridine Chemical Properties,Usage,Production

Synthesis

16867-03-1

24424-99-5

902835-93-2

General procedure for the synthesis of tert-butyl (3-hydroxypyridin-2-yl)carbamate from 2-amino-3-hydroxypyridine and di-tert-butyl dicarbonate: 2-amino-3-hydroxypyridine (1 mmol) was added to a reaction vial containing a magnetic stirrer, followed by the addition of guanidine hydrochloride (15 mol%) and di-tert-butyl dicarbonate (1.2 mmol) to an ethanol (1 mL) solution. The reaction mixture was stirred at 35-40 °C until the reaction was complete (monitored by TLC or GC). Upon completion of the reaction, the ethanol is evaporated under vacuum and the residue is washed with water to remove the catalyst or dissolved in dichloromethane (or ethyl acetate) and the catalyst is separated by filtration. If an organic solvent is used for post-treatment, evaporation of the organic solvent gives an almost pure product. If excess di-tert-butyl dicarbonate has been used, the product can be washed with petroleum ether or hexane to recover the residual di-tert-butyl dicarbonate. If necessary, the product can be further purified by crystallization (using a solvent mixture of hexane and dichloromethane, or ethyl ether and petroleum ether) or silica gel column chromatography (using ethyl acetate-hexane (1:6) as eluent).

References

[1] Tetrahedron Letters, 2011, vol. 52, # 12, p. 1260 - 1264
[2] Monatshefte fur Chemie, 2011, vol. 142, # 10, p. 1035 - 1043

2-(BOC-aMino)-3-hydroxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(BOC-aMino)-3-hydroxypyridine Suppliers

China 37 India 2 United States 3 Global 42
Synthonix Inc
Tel
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Fax
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Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Combi-Blocks Inc.
Tel
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Fax
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Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Matrix Scientific
Tel
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Fax
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Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
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View Lastest Price from 2-(BOC-aMino)-3-hydroxypyridine manufacturers

Career Henan Chemical Co
Product
2-(BOC-aMino)-3-hydroxypyridine 902835-93-2
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2019-12-21

902835-93-2, 2-(BOC-aMino)-3-hydroxypyridineRelated Search:

Luminol N-(5-Chloro-3-hydroxy-2-pyridinyl)carbamic acid 1,1-dimethylethyl ester 2-Amino-5-iodopyridine 3,5-Dibromo-2-pyridylamine tert-butyl 5-bromo-3-hydroxypyridin-2-ylcarbamate

  • 2-(BOC-aMino)-3-hydroxypyridine
  • N-(3-Hydroxy-2-pyridinyl)carbamic acid 1,1-dimethylethyl ester
  • tert-Butyl (3-hydroxypyridin-2-yl)carbamate
  • Carbamic acid, N-(3-hydroxy-2-pyridinyl)-, 1,1-dimethylethyl ester
  • 902835-93-2