H-D-TYR-OME HCL
- Product Name
- H-D-TYR-OME HCL
- CAS No.
- 3728-20-9
- Chemical Name
- H-D-TYR-OME HCL
- Synonyms
- H-D-Tyr-OMe;D-Tyr-OMe·HCl;H-D-TYR-OME HCL;H-D-Tyr-OMe·HCI;H-D-Try-OMe-HCl;D-TYROSINE-OME HCL;Tirofiban Impurity 45;D-TYROSINE ETHYL OME HCl;H-D-Tyr-OMe hydrochloride;H-D-TYR-OME HCL USP/EP/BP
- CBNumber
- CB0268840
- Molecular Formula
- C10H14ClNO3
- Formula Weight
- 231.68
- MOL File
- 3728-20-9.mol
H-D-TYR-OME HCL Property
- Melting point:
- 177-179℃
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- color
- White to off-white
- CAS DataBase Reference
- 3728-20-9(CAS DataBase Reference)
Safety
- HS Code
- 2922500090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M332530
- Product name
- MethylD-TyrosinateHydrochloride
- Packaging
- 2.5g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- M332530
- Product name
- MethylD-TyrosinateHydrochloride
- Packaging
- 10g
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 237261
- Product name
- D-Tyrosine methyl ester hydrochloride 98+%
- Packaging
- 5g
- Price
- $170
- Updated
- 2021/12/16
- Product number
- 290842
- Product name
- D-Tyrosine methyl ester hydrochloride
- Packaging
- 5g
- Price
- $380
- Updated
- 2021/12/16
- Product number
- 03900
- Product name
- D-Tyrosinemethylesterhydrochloride,≥98%(HPLC)
- Purity
- ≥98%(HPLC)
- Packaging
- 5G
- Price
- $17.47
- Updated
- 2021/12/16
H-D-TYR-OME HCL Chemical Properties,Usage,Production
Chemical Properties
Crystalline
Uses
D-Tyrosine methyl ester hydrochloride is an intermediate in the synthesis of oxybutynin chloride (O868525), an inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.
Synthesis
67-56-1
556-02-5
3728-20-9
General procedure for the synthesis of methyl (R)-2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride from methanol and D-tyrosine: (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid (49) (1.07 g, 5.9 mmol) was dissolved in methanol, and the reaction was completed to give methyl (2R)-2-amino-3-(4-hydroxyphenyl)propanoate (50) . The product characterization data were as follows: melting point 176°C (literature values in agreement); 1H NMR (DMSO-d6) δ: 6.82 (d, J = 8.4 Hz, 2H, ArH3' and ArH5'), 4.13 (t, J = 6.9 Hz, 1H, H2), 3.83 (s, 3H, OCH3), 3.22 (dd, J = 6.0, 14.4 Hz. 1H, 3Ha), 3.12 (dd, J = 6.9, 14.7 Hz, 1H, 3Hb). Mass spectrum (chemical ionization, positive ion mode) m/z: 196 (100%) [M+]. High Resolution Mass Spectrometry (HRMS) calculated value of C10H14NO3: 196.0974, measured value: 196.0985.
References
[1] Organic Letters, 2002, vol. 4, # 2, p. 265 - 267
[2] Organic and Biomolecular Chemistry, 2007, vol. 5, # 4, p. 636 - 643
[3] Patent: WO2006/74501, 2006, A1. Location in patent: Page/Page column 152
[4] Tetrahedron, 2008, vol. 64, # 49, p. 11270 - 11290
[5] Organic and Biomolecular Chemistry, 2005, vol. 3, # 7, p. 1233 - 1239
H-D-TYR-OME HCL Preparation Products And Raw materials
Raw materials
Preparation Products
H-D-TYR-OME HCL Suppliers
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View Lastest Price from H-D-TYR-OME HCL manufacturers
- Product
- H-D-TYR-OME HCL 3728-20-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2025-08-11
- Product
- H-D-TYR-OME HCL 3728-20-9
- Price
- US $3.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000
- Release date
- 2024-09-05
- Product
- H-D-TYR-OME HCL 3728-20-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-21