ChemicalBook > CAS DataBase List > N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine

N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine

Product Name
N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine
CAS No.
1253282-31-3
Chemical Name
N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine
Synonyms
Fmoc-Aph(Hor)-OH;Fmoc-4-Aph(Hor)-OH;Fmoc-4Aph(Hor);Fmoc-L-Aph(Hor);Fmoc-4-Aph(L-Hor);Fmoc-Aph(L-Hor)-OH;Fmoc-D-Aph(D-H)-OH;Fmoc-D-4Aph(Hor)-OH;FMoc-L-Aph(L-Hor)-OH;Fmoc-4-Aph(L-Hor)-OH
CBNumber
CB02705260
Molecular Formula
C29H26N4O7
Formula Weight
542.54
MOL File
1253282-31-3.mol
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N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine Property

Melting point:
>222°C (dec.)
Density 
1.412±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Sonicated)Methanol (Slightly, Heated, Sonicated)
pka
3.77±0.10(Predicted)
form 
Solid
color 
White to Off-White
InChIKey
TYZSMQUWFLKJFB-ZEQRLZLVSA-N
SMILES
C(O)(=O)[C@H](CC1=CC=C(NC([C@@H]2CC(=O)NC(=O)N2)=O)C=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference
1253282-31-3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
F647563
Product name
Fmoc-Aph(Hor)-OH(~10%THF)(Degarelixintermediate)
Packaging
100mg
Price
$45
Updated
2021/12/16
ChemPep
Product number
180198
Product name
Fmoc-Aph(Hor)-OH
Packaging
1g
Price
$150
Updated
2021/12/16
Activate Scientific
Product number
AS112751
Product name
Fmoc-D-Aph(D-H)-OH
Purity
95%
Packaging
25mg
Price
$209
Updated
2021/12/16
Activate Scientific
Product number
AS112751
Product name
Fmoc-D-Aph(D-H)-OH
Purity
95%
Packaging
100mg
Price
$283
Updated
2021/12/16
AK Scientific
Product number
9490AL
Product name
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-((S)-2,6-dioxohexahydropyrimidine-4-carboxamido)phenyl)propanoicacid
Packaging
100mg
Price
$397
Updated
2021/12/16
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N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine Chemical Properties,Usage,Production

Uses

Fmoc-Aph(Hor)-OH (CAS# 1253282-31-3) is an intermediate of degarelix, a pharmeceutical hormone used in the treatment of prostate cancer. Fmoc-Aph(Hor)-OH has been used as a building block in peptide elongation reactions.

N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine Suppliers

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View Lastest Price from N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine manufacturers

Hebei Mingeng Biotechnology Co., Ltd
Product
Fmoc-Aph(Hor)-OH 1253282-31-3
Price
US $150.00/ASSAYS
Min. Order
10g
Purity
more than 99.6%
Supply Ability
500kg/month
Release date
2021-11-24
Career Henan Chemical Co
Product
N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine 1253282-31-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-15

1253282-31-3, N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanineRelated Search:

FMOC-D-4-Chlorophe FMOC-LYS(BOC)(ISOPROPYL)-OH Fmoc-Lys(nicotinoyl)-OH (R)-N-Acetyl-2-naphthylalanine Fmoc-D-Asn(Trt)-OH 4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Fmoc-D-homoArg(Et)2-OH·HCl Fmoc-Lys(Pal-Glu-OtBu)-OH (R)-N-Fmoc-(3-Pyridyl)alanine H-GLU-OTBU Fmoc-8-amino-3,6-dioxaoctanoic acid FMOC-D-GLU-OTBU Fmoc-3-(2-Naphthyl)-D-alanine Fmoc-N-Me-Tyr(tBu)-OH FMOC-D-CIT-OH FMOC-D-alanine (9H-Fluoren-9-yl)MethOxy]Carbonyl HomoArg(Et)2-OH·HCl (symmetrical) Fmoc-Lys(Octa(OtBu)-Glu(α-OtBu)-AEEA-AEEA)-OH

  • (S)-2-(Fmoc-amino)-3-[4-[(S)-2,6-dioxohexahydropyrimidine-4-carboxamido]phenyl]propanoic Acid
  • (2S)-3-{4-[(4S)-2,6-dioxo-1,3-diazinane-4-amido]phenyl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • Fmoc-Aph(Hor)-OH
  • FMoc-L-Aph(L-Hor)-OH
  • N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-((S)-2,6-dioxohexahydropyrimidine-4-carboxamido)phenyl)propanoic acid
  • Fmoc-D-Aph(D-H)-OH
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl L-Aph(L-Hor)-OH
  • Fmoc-4-Aph(L-Hor)
  • Fmoc-Aph(L-Hor)-OH
  • Fmoc-D-4-Aph(L-Hor)-OH
  • Fmoc-4-Aph(Hor)-OH
  • L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-
  • Fmoc-Aph(Hor)-OH (~10% THF) (Degarelix intermediate)
  • Fmoc-4Aph(Hor)
  • Fmoc-D-4Aph(Hor)-OH
  • (2S)-3-[4-[[(4S)-2,6-dioxo-1,3-diazinane-4-carbonyl]amino]phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
  • Fmoc-4-Aph(L-Hor)-OH
  • Fmoc-L-Aph(Hor)
  • N-Fmoc-4-[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonylamino]-L-phenylalanine
  • 1253282-31-3
  • C29H26N4O7