Sorafenib related coMpound 8

Product Name: Sorafenib related coMpound 8
CAS No.: 1431697-81-2
Chemical Name: Sorafenib related coMpound 8
Synonyms: SL-CLYG;Sorafenib impurity V;Sorafenib impurities2;Sorafenib impurities163;Sorafenib 2-Chloro Analog;Sorafenib related coMpound 8;Sorafenib Related Compound 20;Sorafenib Tosilate - Impurity H;4-(4-(3-(2-chloro-3-(trifluoromethyl);Sorafenib 2-Chloro Analog/ 4-Deschloro 2-Chloro Sorafenib
CBNumber: CB02707219
Molecular Formula: C21H16ClF3N4O3
Formula Weight: 464.82
MOL File: 1431697-81-2.mol

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Sorafenib related coMpound 8 Property

Boiling point:: 520.0±50.0 °C(Predicted)
Density: 1.454±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 12.84±0.70(Predicted)
color: White to Pale Yellow
Major Application: pharmaceutical
InChI: 1S/C21H16ClF3N4O3/c1-26-19(30)17-11-14(9-10-27-17)32-13-7-5-12(6-8-13)28-20(31)29-16-4-2-3-15(18(16)22)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
InChIKey: JWAKXXCHFJSKRN-UHFFFAOYSA-N
SMILES: FC(F)(F)c1c(c(ccc1)NC(=O)Nc2ccc(cc2)Oc3cc(ncc3)C(=O)NC)Cl

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Safety

WGK Germany: WGK 3
HS Code: 2933399090
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Aquatic Acute 1
Aquatic Chronic 1
Lact.
Repr. 1B
STOT RE 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H362May cause harm to breast-fed children

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: D291115
Product name: 4-Deschloro-2-chloro-Sorafenib
Packaging: 10mg
Price: $190
Updated: 2021/12/16

TRC

Product number: D291115
Product name: 4-Deschloro-2-chloro-Sorafenib
Packaging: 100mg
Price: $1390
Updated: 2021/12/16

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Sorafenib related coMpound 8 Chemical Properties,Usage,Production

Uses

4-Deschloro-2-chloro-Sorafenib is a derivative of Sorafenib (S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.

Sorafenib related coMpound 8 Preparation Products And Raw materials

Raw materials

Preparation Products

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Sorafenib related coMpound 8 Suppliers

China 60 India 2 United States 3 Global 65

Adamas Reagent, Ltd.

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View Lastest Price from Sorafenib related coMpound 8 manufacturers

Career Henan Chemical Co

Product: Sorafenib related coMpound 8 1431697-81-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99.99%
Supply Ability: 200kg
Release date: 2019-12-23

1431697-81-2, Sorafenib related coMpound 8Related Search:

Sorafenib 3-Amino-2-chlorobenzotrifluoride Sorafenib Impurity 6 Sorafenib IMpurity C 4-(4-Aminophenoxy)-N-methylpicolinamide Sorafenib related coMpound 1 Sorafenib Related Compound 13 Sorafenib related coMpound 5 Sorafenib Impurity 1 Sorafenib related coMpound 7 Sorafenib related compound 11 N-Methyl-4-chloropyridine-2-carboxamide Sorafenib Related Compound 22 Sorafenib related coMpound 6 1-(4-chloro-3-(trifluoromethyl)phenyl)urea ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine TICAGRELOR

Sorafenib related coMpound 8

Sorafenib 2-Chloro Analog

Sorafenib Related Compound 20

Sorafenib impurity 4/4-Deschloro-2-chloro-Sorafenib/4-(4-(3-(2-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

4-(4-(3-(2-chloro-3-(trifluoromethyl)

Sorafenib impurity V

2-Pyridinecarboxamide, 4-[4-[[[[2-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-

4-[4-({[2-chloro-3-(trifluoromethyl)phenyl]carbamo yl}amino)phenoxy]-N-methylpyridine-2-carboxamide

Sorafenib 2-Chloro Analog/ 4-Deschloro 2-Chloro Sorafenib

Sorafenib impurities163

Sorafenib impurities2

Sorafenib Tosilate - Impurity H

SL-CLYG

4-[4-[[[2-Chloro-3-(trifluoromethyl)phenyl]carbamoyl]amino]phenoxy]-N-methylpyridine-2-carboxamide (Sorafenib Tosilate - Impurity H)

Sorafenib EP Impurity H (Sorafenib USP Related Compound H)

1431697-81-2

5623-18-9