4-Chloro-N-methylpicolinamide
- Product Name
- 4-Chloro-N-methylpicolinamide
- CAS No.
- 220000-87-3
- Chemical Name
- 4-Chloro-N-methylpicolinamide
- Synonyms
- 4-Chloro-N-methylpicolinamide;4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE;4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE;oro-N-methyL;Sorafenib INT3;4-Chloropyridine-2;IFLAB-BB F2108-0189;-2-pyridinecarboxamide;Sorafenib impurities13;Sorafenib tosylate INT II
- CBNumber
- CB6134053
- Molecular Formula
- C7H7ClN2O
- Formula Weight
- 170.6
- MOL File
- 220000-87-3.mol
4-Chloro-N-methylpicolinamide Property
- Melting point:
- 41-43°C
- Boiling point:
- 317.8±27.0 °C(Predicted)
- Density
- 1.264±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
- form
- Solid
- pka
- 13.41±0.46(Predicted)
- color
- Off-White to Light Yellow
- CAS DataBase Reference
- 220000-87-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C2793
- Product name
- 4-Chloro-N-methyl-2-pyridinecarboxamide
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $33
- Updated
- 2024/03/01
- Product number
- C2793
- Product name
- 4-Chloro-N-methyl-2-pyridinecarboxamide
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $132
- Updated
- 2024/03/01
- Product number
- H50535
- Product name
- 4-Chloro-N-methylpyridine-2-carboxamide, 97%
- Packaging
- 250mg
- Price
- $64.65
- Updated
- 2024/03/01
- Product number
- H50535
- Product name
- 4-Chloro-N-methylpyridine-2-carboxamide, 97%
- Packaging
- 1g
- Price
- $216.65
- Updated
- 2024/03/01
- Product number
- C379950
- Product name
- 4-Chloro-N-methylpyridine-2-carboxamide(>90%)
- Packaging
- 25g
- Price
- $440
- Updated
- 2021/12/16
4-Chloro-N-methylpicolinamide Chemical Properties,Usage,Production
Description
4-Chloro-N-methylpicolinamide is a polar organic compound that interacts with hydrogen bonds. It has been shown to inhibit the value-added of cancer cells by inhibiting protein synthesis to inhibit the growth of human hepatocellular carcinoma cells, bcr/abl kinase, and hct116 cells, and is a candidate for cancer treatment. Studies have shown that it also inhibits the proliferation of MDA-MB231 breast cancer cells by blocking growth factor activity. In addition, 4-Chloro-N-methylpicolinamide is a pharmaceutical intermediate component used in the preparation of the antineoplastic drugs regorafenib and sorafenib.
Chemical Properties
Pale-Yellow Solid
Uses
4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis.
4-Chloro-N-methylpicolinamide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chloro-N-methylpicolinamide manufacturers
- Product
- N-Methyl-4-chloropyridine-2-carboxamide 220000-87-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-26
- Product
- N-Methyl-4-chloropyridine-2-carboxamide 220000-87-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-26
- Product
- N-Methyl-4-chloropyridine-2-carboxamide 220000-87-3
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-14