ChemicalBook > CAS DataBase List > 4-Chloro-N-methylpicolinamide

4-Chloro-N-methylpicolinamide

Product Name
4-Chloro-N-methylpicolinamide
CAS No.
220000-87-3
Chemical Name
4-Chloro-N-methylpicolinamide
Synonyms
4-Chloro-N-methylpicolinamide;4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE;4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE;oro-N-methyL;Sorafenib INT3;CAS:220000-87-3;4-Chloropyridine-2;IFLAB-BB F2108-0189;Sorafenib Impurity 06;-2-pyridinecarboxamide
CBNumber
CB6134053
Molecular Formula
C7H7ClN2O
Formula Weight
170.6
MOL File
220000-87-3.mol
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4-Chloro-N-methylpicolinamide Property

Melting point:
41-43°C
Boiling point:
317.8±27.0 °C(Predicted)
Density 
1.264±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
form 
Solid
pka
13.41±0.46(Predicted)
color 
Off-White to Light Yellow
InChI
InChI=1S/C7H7ClN2O/c1-9-7(11)6-4-5(8)2-3-10-6/h2-4H,1H3,(H,9,11)
InChIKey
BGVBBMZMEKXUTR-UHFFFAOYSA-N
SMILES
C1(C(NC)=O)=NC=CC(Cl)=C1
CAS DataBase Reference
220000-87-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C2793
Product name
4-Chloro-N-methyl-2-pyridinecarboxamide
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$33
Updated
2025/07/31
TCI Chemical
Product number
C2793
Product name
4-Chloro-N-methyl-2-pyridinecarboxamide
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$132
Updated
2025/07/31
TRC
Product number
C379950
Product name
4-Chloro-N-methylpyridine-2-carboxamide(>90%)
Packaging
25g
Price
$440
Updated
2021/12/16
AK Scientific
Product number
V0241
Product name
4-Chloro-N-methyl-2-pyridinecarboxamide
Packaging
1g
Price
$14
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20299
Product name
4-Chloro-N-methylpyridine-2-carboxamide
Packaging
25g
Price
$45
Updated
2021/12/16
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4-Chloro-N-methylpicolinamide Chemical Properties,Usage,Production

Description

4-Chloro-N-methylpicolinamide is a polar organic compound that interacts with hydrogen bonds. It has been shown to inhibit the value-added of cancer cells by inhibiting protein synthesis to inhibit the growth of human hepatocellular carcinoma cells, bcr/abl kinase, and hct116 cells, and is a candidate for cancer treatment. Studies have shown that it also inhibits the proliferation of MDA-MB231 breast cancer cells by blocking growth factor activity. In addition, 4-Chloro-N-methylpicolinamide is a pharmaceutical intermediate component used in the preparation of the antineoplastic drugs regorafenib and sorafenib.

Chemical Properties

Pale-Yellow Solid

Uses

4-Chloro-N-methylpyridine-2-carboxamide (>90%) (cas# 220000-87-3) is a compound useful in organic synthesis.

4-Chloro-N-methylpicolinamide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-N-methylpicolinamide Suppliers

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View Lastest Price from 4-Chloro-N-methylpicolinamide manufacturers

Jinan Ruitong Biotech Co., Ltd.
Product
4-Chloro-N-methyl-2-pyridinecarboxamide. 220000-87-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-08-27
Shandong Jihui Chemical Co., Ltd.
Product
N-Methyl-4-chloropyridine-2-carboxamide 220000-87-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
Purity: 98%
Supply Ability
50tons
Release date
2025-07-21
Henan Aochuang Chemical Co.,Ltd.
Product
N-Methyl-4-chloropyridine-2-carboxamide 220000-87-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-29

220000-87-3, 4-Chloro-N-methylpicolinamideRelated Search:

Methylparaben N,N-Dimethylformamide Kresoxim-methyl Bensulfuron methyl Methyl acrylate Methyl acetate N-Methylformamide 2-Picoline PYRIDINE-2-CARBOXAMIDE 2,2'-(Butylimino)diethanol N-Benzylethanolamine 3-Amino-2-chlorobenzotrifluoride Thiophanate-methyl Methyl Sorafenib IMpurity Sorafenib related coMpound 8 Sorafenib related compound 10 Sorafenib Related Compound 21

  • IFLAB-BB F2108-0189
  • 4-CHLORO-N-METHYLPYRIDINE-2-CARBOXAMIDE
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  • 2-(N-MethylcarbaMoyl)-4-chloropyridine
  • 4-Chloro-N-Methylpyridine-2-CarboxaMide 2-carboxaMide
  • 4-Chloro-N-Methylpyridine-2-carboxaMide (>90%)
  • 4-Chloro-N-Methyl-2-pyridinecarboxaMide, >95%
  • 4-Chloro-<i>N</i>-methylpyridine-2-carboxamide
  • Sorafenib INT3
  • N-Methyl-4-chloropyridine-2-carboxamide(220000-87-3)
  • 4-Chloropyridine-2
  • 4-Chloro-N-methyl-2-pyridinecarboxamide Sorafenib Intermediates I
  • Sorafenib tosylate INT II
  • 4-Chloro-N-methyl-2-pyridinecarboxamide 97%
  • 4-Chloro-N-methyl-2-pyridinecarboxamide &gt
  • oro-N-methyL
  • -2-pyridinecarboxamide
  • 4-CHLORO-N-METHYL-2-PYRIDENECARBOXAMIDE
  • N-Methyl-4-chloropyridine-2-carboxamide ISO 9001：2015 REACH
  • Sorafenib tosylate Impurity P
  • 4-Chloro-N-methyl-2-pyridinecarboxamide (Sorafenib Impurity)
  • Sorafenib impurities13
  • (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide)Q: What is (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) Q: What is the CAS Number of (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) Q: What is the storage condition of (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide) Q: What are the applications of (4-Chloro-(2-Pyridyl)-N-Methyl Carboxamide)
  • 4-Chloro-N-methylpyridine-2-carboxamide,97%
  • N-methyl-4-chloro-2-pyridinecarbonamide
  • Sorafenib Impurity INT-1-B
  • CAS:220000-87-3
  • 4-Chloro-N-methylpyridin-2-carboxamide
  • 4-Chloro-N-methylpicolimide
  • Sorafenib Impurity 06
  • 220000-87-3
  • Pyridine
  • Amines
  • Aromatics
  • Heterocycles
  • blocks
  • Carboxes
  • Pyridines
  • 220000-87-3