Ethyl 1-Boc-3-pyrrolidinecarboxylate

Product Name: Ethyl 1-Boc-3-pyrrolidinecarboxylate
CAS No.: 170844-49-2
Chemical Name: Ethyl 1-Boc-3-pyrrolidinecarboxylate
Synonyms: ETHYL 1-BOC-BETA-PROLINATE;N-Boc- 3-ethyl pyrrolidine-;N-Boc-DL-beta-proline ethyl ester;N-Boc-DL-^b-prolineethylester,97%;ETHYL 1-BOC-3-PYRROLIDINECARBOXYLATE;N-Boc-DL-^b-proline ethyl ester, 97%;1-BOC- pyrrolidine -3- ethyl formate;Ethyl 1-Boc-pyrrolidine-3-carboxylate;N-Boc- 3-ethyl pyrrolidine- carboxylate;N-Boc-3-Pyrrolidinecaboxylic acid ethyl ester
CBNumber: CB0271930
Molecular Formula: C12H21NO4
Formula Weight: 243.3
MOL File: 170844-49-2.mol

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Ethyl 1-Boc-3-pyrrolidinecarboxylate Property

Boiling point:: 305.6±35.0 °C(Predicted)
Density: 1.100±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: solid
pka: -2.57±0.40(Predicted)
Appearance: Colorless to light yellow Liquid
CAS DataBase Reference: 170844-49-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ADE000025
Product name: Pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
Purity: Aldrich
Packaging: 1g
Price: $216
Updated: 2025/07/31

TRC

Product number: E926130
Product name: Ethyl1-BOC-3-pyrrolidinecarboxylate
Packaging: 1g
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 018168
Product name: Pyrrolidine-1,3-dicarboxylic acid1-tert-butyl ester 3-ethyl ester
Packaging: 1g
Price: $42
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB143044
Product name: 1-tert-Butyl 3-ethyl pyrrolidine-1,3-dicarboxylate
Packaging: 1g
Price: $61
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB143044
Product name: 1-tert-Butyl 3-ethyl pyrrolidine-1,3-dicarboxylate
Packaging: 2g
Price: $106
Updated: 2021/12/16

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Ethyl 1-Boc-3-pyrrolidinecarboxylate Chemical Properties,Usage,Production

Synthesis

72925-15-6

24424-99-5

170844-49-2

A dichloromethane (50 mL) solution of di-tert-butyl dicarbonate (10.30 g, 47.2 mmol) was slowly added dropwise to a dichloromethane (50 mL) solution of crude ethyl 3-pyrrolidinecarboxylate (7.12 g) at 0 °C for a controlled time of 10 min or more. The reaction mixture was gradually warmed up to room temperature over 18 h. The mixture was washed with water and saturated saline, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford ethyl N-Boc-3-pyrrolidinecarboxylate (10.4 g, 100% yield), which could be used for the subsequent reaction without further purification.1H NMR (CDCl3) δ: 4.14 (q, 2H), 3.27-3.69 (m , 4H), 3.02 (m, 1H), 2.07-2.16 (m, 2H), 1.46 (s, 9H), 1.27 (t, 3H).

References

[1] Patent: WO2005/49602, 2005, A1. Location in patent: Page/Page column 89; 90; 130
[2] Patent: WO2005/49605, 2005, A1. Location in patent: Page/Page column 117; 118; 158

Ethyl 1-Boc-3-pyrrolidinecarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 1-Boc-3-pyrrolidinecarboxylate Suppliers

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View Lastest Price from Ethyl 1-Boc-3-pyrrolidinecarboxylate manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Ethyl 1-Boc-3-pyrrolidinecarboxylate 170844-49-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: 1-Boc-3-hydroxymethylpyrrolidine 170844-49-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-25

170844-49-2, Ethyl 1-Boc-3-pyrrolidinecarboxylateRelated Search:

Ethyl acrylate Ethanol Ethyl formate Ethyl acetate Ethyl cyanoacetate BUTYL OLEATE 3-Pyrrolidinecarboxylic acid OXALIC ACID Tris(trimethylsilyl)phosphate Crospovidone Polyvinylpyrrolidone ISOXADIFEN-ETHYL Sodium L-pyroglutamate Pyrrolidine Ethylparaben Butyl acetate Trinexapac-ethyl N-Methyl-2-pyrrolidone

ETHYL 1-BOC-3-PYRROLIDINECARBOXYLATE

PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-ETHYL ESTER

ETHYL 1-BOC-BETA-PROLINATE

N-Boc- 3-ethyl pyrrolidine- carboxylate

N-Boc-3-Pyrrolidinecaboxylic acid ethyl ester

1-tert-butyl 3-ethylpyrrolidine-1,3-dicarboxylate

N-Boc-DL-^b-proline ethyl ester, 97%

N-Boc- 3-ethyl pyrrolidine-

Ethyl 1-Boc-pyrrolidine-3-carboxylate

1-Boc-pyrrolidine-3-carboxylic acid ethyl ester

N-Boc-pyrrolidine-3-carboxylic acid ethyl ester

1-Boc-3-pyrrolidinecarboxylic acid ethyl ester

tert-butyl ethyl pyrrolidine-1,3-dicarboxylate

1,3-Pyrrolidinedicarboxylicacid, 1-(1,1-dimethylethyl) 3-ethyl ester

N-Boc-DL-beta-proline ethyl ester

N-Boc-DL-^b-prolineethylester,97%

Ethyl 1-Boc-3-pyrrolidinecarboxylate USP/EP/BP

1-BOC- pyrrolidine -3- ethyl formate

Ethyl 1-Boc-pyrrolidine-3-carboxylate - [E12992]

170844-49-2

170844-49-3

pharmacetical

Acids and Derivatives

Amino Acids and Derivatives