Volitinib

ChemicalBook > CAS DataBase List > Volitinib

Product Name: Volitinib
CAS No.: 1313725-88-0
Chemical Name: Volitinib
Synonyms: Savolitinib;HMPL-504;Savolitinib (AZD6094);CS-2676;Volitinib;AZD-6094);EOS-60799;HMPL0-504;Volitinib USP/EP/BP;AZD-6094 (VOLITINIB)
CBNumber: CB02731160
Molecular Formula: C17H15N9
Formula Weight: 345.36
MOL File: 1313725-88-0.mol

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Volitinib Property

Melting point:: 205-207°C
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 5.67±0.50(Predicted)
form: Solid
color: Pale Beige
CAS DataBase Reference: 1313725-88-0

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger

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N-Bromosuccinimide Price

TRC

Product number: S142903
Product name: Savolitinib
Packaging: 100mg
Price: $1215
Updated: 2021/12/16

ChemScene

Product number: CS-4062
Product name: Savolitinib
Purity: 99.56%
Packaging: 100mg
Price: $850
Updated: 2021/12/16

ChemScene

Product number: CS-4062
Product name: Savolitinib
Purity: 99.56%
Packaging: 5mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BV160378
Product name: Volitinib
Packaging: 5mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BV160378
Product name: Volitinib
Packaging: 50mg
Price: $600
Updated: 2021/12/16

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Volitinib Chemical Properties,Usage,Production

Description

Savolitinib selectively inhibits the MET receptor, blocking the PI3K/AKT/MAPK-signaling pathway as well as downregulating MYC.

Uses

Savolitinib is a potent and highly selective c-Met inhibitor. Savoltinib demonstrated anti-tumor efficacy in a panel of cMet-dysregulated gastric cancer PDX models. Savolitinib also demonstrated good antitmuor activities.

Clinical Use

It is currently being evaluated in phase I clinical trials in combination with EGFR TKIs in NSCLC patients.

Volitinib Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Volitinib manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: Savolitinib 1313725-88-0
Price: US $38.99/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2021-12-27

Dideu Industries Group Limited

Product: Volitinib 1313725-88-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-05

Career Henan Chemical Co

Product: (S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine 1313725-88-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2020-01-01

1313725-88-0, VolitinibRelated Search:

3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione INCB39110 X-376 Filgotinib Decernotinib Masitinib Lestaurtinib CAL-101 PLX3397 (Pexidartinib) CO-1686 Momelotinib Verteporfin PLX4032 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol AZD-6244 ARRY-334543 SU 6668 Ibrutinib

AZD6094,Volitinib, HMPL-504, Savolitinib

1-[(1S)-1-Imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine

(S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine

Volitinib

Savolitinib

HMPL-504(AZD6094, Volitinib)

EOS-60799

AZD-6094)

HMPL-504

Savolitinib (Volitinib

(S)-1-(1-(imidazo[1,2-a] yridine-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazine

Savolitinib (AZD6094)

(S)-1-(1-(IMIDAZO[1,2-A]

HMPL-504; HMPL504; HMPL504; AZD-6094; AZD 6094; AZD6094

Volitinib (Savolitinib, AZD-6094)

CS-2676

VOLITINIB; HMPL504; AZD-6094;VOLITINIB; HMPL-504; AZD6094; HMPL 504; AZD 6094

Savolitinib(AZD6094, HMPL-504)

1H-1,2,3-Triazolo[4,5-b]pyrazine, 1-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-

Volitinib USP/EP/BP

4-{1-[(1S)-1-{imidazo[1,2-a]pyridin-6-yl}ethyl]-1H-[ 1,2,3]triazolo[4,5-b]pyrazin-6-yl}-1-methyl-1H-pyra zole

Pharmaceutical Intermediate Volitinib

AZD-6094 (VOLITINIB)

VOLITINIB (AZD6094, SAVOLITINIB)

HMPL0-504

Savolitinib, 10 mM in DMSO

1313725-88-0

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