6-Bromo-1H-indol-4-amine

Product Name: 6-Bromo-1H-indol-4-amine
CAS No.: 350800-81-6
Chemical Name: 6-Bromo-1H-indol-4-amine
Synonyms: 4-AMINO-6-BROMOINDOLE;6-BROMO-4-AMINOINDOLE;6-BROMOINDOL-4-YLAMINE;6-bromo-1H-indol-4-amine;4-Amino-6-bromo-1H-indole;1H-Indol-4-aMine, 6-broMo-
CBNumber: CB0277482
Molecular Formula: C8H7BrN2
Formula Weight: 211.06
MOL File: 350800-81-6.mol

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6-Bromo-1H-indol-4-amine Property

storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 296898
Product name: 6-Bromo-1H-indol-4-amine
Packaging: 250.00mg
Price: $43
Updated: 2026/05/19

Chem-Impex

Product number: 20905
Product name: 4-Amino-6-bromoindole
Packaging: 100MG
Price: $93.14
Updated: 2026/05/19

Matrix Scientific

Product number: 296898
Product name: 6-Bromo-1H-indol-4-amine
Packaging: 1.00g
Price: $110
Updated: 2026/05/19

Chem-Impex

Product number: 20905
Product name: 4-Amino-6-bromoindole
Packaging: 250MG
Price: $174.66
Updated: 2026/05/19

Matrix Scientific

Product number: 296898
Product name: 6-Bromo-1H-indol-4-amine
Packaging: 5.00g
Price: $337
Updated: 2026/05/19

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6-Bromo-1H-indol-4-amine Chemical Properties,Usage,Production

Synthesis

350800-78-1

350800-81-6

To 6-bromo-1H-indol-4-amine (3 g, 9.49 mmol) was added HCl solution (61.20 g, 167.86 mmol) of TiCl3 (7.32 g, 47.45 mmol). The reaction mixture was stirred at 25 °C for 16 hours. After completion of the reaction, the mixture was slowly poured into 2N aqueous NaOH solution (150 mL) and extracted with EtOAc (150 mL). The organic phase was dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: petroleum ether to petroleum ether/ethyl acetate = 5/1) to afford 6-bromo-1H-indol-4-amine (2 g, 36% yield) as a gray solid.1H NMR (CDCl3, 400 MHz) δ 8.10 (br s, 1H), 7.09-7.08 (m, 1H), 7.02 (d, J = 1.4Hz , 1H), 6.54 (d, J = 1.4Hz, 1H), 6.44-6.43 (m, 1H), 3.98 (br s, 2H).

References

[1] Patent: WO2016/168682, 2016, A2. Location in patent: Paragraph 0256
[2] European Journal of Medicinal Chemistry, 2001, vol. 36, # 2, p. 165 - 178

6-Bromo-1H-indol-4-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Bromo-1H-indol-4-amine Suppliers

China 59 India 1 Switzerland 2 United Kingdom 4 United States 11 Global 77

Shanghai Hanhong Scientific Co.,Ltd.

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View Lastest Price from 6-Bromo-1H-indol-4-amine manufacturers

Career Henan Chemical Co

Product: 4-AMINO-6-BROMOINDOLE 350800-81-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-09

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350800-81-6