ChemicalBook > CAS DataBase List > 3,5-Diiodo-L-thyronine

3,5-Diiodo-L-thyronine

Product Name
3,5-Diiodo-L-thyronine
CAS No.
1041-01-6
Chemical Name
3,5-Diiodo-L-thyronine
Synonyms
3,5-T2;diiodothyronine;L-T2;Nsc90469;abs42008180;L-Diiodothyronine;Diiodo-L-thyronine;5-Chloro-3,3’3,5-diiodothyronine;L-3,5-Diiodothyronine
CBNumber
CB0277992
Molecular Formula
C15H13I2NO4
Formula Weight
525.08
MOL File
1041-01-6.mol
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3,5-Diiodo-L-thyronine Property

Melting point:
255-260 °C (dec.)
Boiling point:
559.4±50.0 °C(Predicted)
Density 
2.095±0.06 g/cm3(Predicted)
vapor pressure 
0.011Pa at 45℃
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
Acidic Alcohol (Slightly), Aqueous Base (Slightly)
form 
Solid
pka
2.15±0.30(Predicted)
color 
White to Light Brown
Water Solubility 
20.147mg/L at 20℃
BRN 
2707891
Stability:
Hygroscopic
InChIKey
ZHSOTLOTTDYIIK-ZDUSSCGKSA-N
LogP
1.1 at 25℃
CAS DataBase Reference
1041-01-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
24/25
WGK Germany 
3
F 
8
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D0629
Product name
3,5-Diiodo-L-thyronine
Purity
thyroid hormone analog
Packaging
500mg
Price
$237
Updated
2024/03/01
Sigma-Aldrich
Product number
D0629
Product name
3,5-Diiodo-L-thyronine
Purity
thyroid hormone analog
Packaging
5g
Price
$1400
Updated
2023/06/20
TCI Chemical
Product number
D1119
Product name
3,5-Diiodo-L-thyronine
Purity
>96.0%(T)
Packaging
1g
Price
$239
Updated
2024/03/01
TCI Chemical
Product number
D1119
Product name
3,5-Diiodo-L-thyronine
Purity
>96.0%(T)
Packaging
5g
Price
$713
Updated
2024/03/01
TCI Chemical
Product number
D1119
Product name
3,5-Diiodo-L-thyronine
Purity
>96.0%(T)
Packaging
100mg
Price
$84
Updated
2024/03/01
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3,5-Diiodo-L-thyronine Chemical Properties,Usage,Production

Chemical Properties

[α] 25 D +25.2° [5 % solution in 1 M HCl:95 % ethanol (1:2)], off-White Solid.

Uses

3,5-Diiodo-L-thyronine is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.

Uses

Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism.

Definition

ChEBI: (2S)-2-amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid is a phenylalanine derivative.

Flammability and Explosibility

Not classified

Pharmacology

3,5-Diiodo-L-thyronine is a thyroid hormone with a l-thyroxine-like activity.

Purification Methods

Recrystallise it from EtOH. [Chambers et al. J Chem Soc 3424 1949, Beilstein 14 II 226, 14 III 1565, 14 IV 2372.]

3,5-Diiodo-L-thyronine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-Diiodo-L-thyronine Suppliers

Americas 1 Canada 2 China 216 Europe 3 Germany 4 India 24 Japan 1 Russia 1 Slovakia 1 South Korea 1 Switzerland 1 United Kingdom 9 United States 38 Global 302
Attix Pharmaceuticals/Darmerica
Tel
--
Fax
--
Email
sales@darmerica.com
Country
Canada
ProdList
964
Advantage
58
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from 3,5-Diiodo-L-thyronine manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
3,5-Diiodo-L-thyronine 1041-01-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-26
Shaanxi Dideu Medichem Co. Ltd
Product
3,5-Diiodo-L-thyronine 1041-01-6
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-07-06
Henan Bao Enluo International TradeCo.，LTD
Product
3,5-Diiodo-L-thyronine 1041-01-6
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-08-02

1041-01-6, 3,5-Diiodo-L-thyronineRelated Search:

H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH Boc-D-Tyr-OH Sodium levothyroxine L-Thyroxine L(+)-Arginine TSH REVERSE T3 3,3',5-Triiodo-L-thyronine Inositol DL-THYROXINE Levothyroxine Impurity 12 3,3',5-TRIIODOTHYROPROPIONIC ACID Thyroxine-4-hydroxy-3,5-diiodophenyl Ether DISCONTINUED 3,5-DIIODO-4'-(4-HYDROXYPHENOXY)BENZOIC ACID N-ForMyl Thyroxine 3,5,3',5'-Tetraiodo Thyroaldehyde 3-IODO-L-TYROSINE 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID

  • 3,5-Diiodi-L-thyronine
  • 3,5-DIIODO-L -THYRONINE 98%
  • 3,5-Diiodo-4-(4-hydroxyphenoxy)-L-phenylalanine, O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine
  • 3,5-Diiodo-O-(4-hydroxyphenyl)-L-tyrosine
  • L-Diiodothyronine
  • Alanine, 3-[4-(p-hydroxyphenoxy)-3,5-diiodophenyl]-, L-
  • Diiodo-L-thyronine
  • L-3,5-Diiodothyronine
  • Nsc90469
  • (2S)-2-aMino-3-[4-(4-hydroxyphenoxy)-3,5-diiodo-phenyl]propanoic acid DIIOD(3,5)-L-THYRONIN
  • 3-[4-(p-Hydroxyphenoxy)-3,5-diiodophenyl]-L-alanine
  • L-T2
  • Levothyroxine Impurity 5（Levothyroxine EP Impurity E）
  • Liothyronine EP Impurity E
  • 5-Chloro-3,3&rsquo
  • 3,5-Diiodo-L-thyronine thyroid horMone analog
  • 3,5-T2
  • Levothyroxine EP Impurity E
  • 3,5-T2 O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine
  • 3,5-Diiodo-<small>L</small>-thyronine
  • diiodothyronine
  • O-(4-HYDROXYPHENYL)-3,5-DIIODO-L-TYROSINE
  • 3,5-DIIODO-L-THYRONINE
  • 3,5-DIIODO-4-(4-HYDROXYPHENOXY)-L-PHENYLALANINE
  • (2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]-propanoic acid
  • L-TYROSINE, O-(4-HYDROXYPHENYL)-3,5-DIIODO-
  • 3-5-diiodo-L-thyronine crystalline
  • 3,5-diiodothyronine
  • 3-[4-p-[Hydroxyphenoxy]-3,5-diiodophenyl] alanine
  • 3,5-Diiodo-L-thyronine &gt
  • (2S)-2-Amino-3-[4-(4-hydroxyphenoxy
  • Diiodomethane-l-Thyronine/T2
  • abs42008180
  • Levothyroxine EP Impurity E (Liothyronine EP Impurity E/ Diiodothyronine/ 3,5-Diiodo-L-thyronine)
  • Liothyronine EP Impurity E (Levothyroxine EP Impurity E/ Diiodothyronine/ 3,5-Diiodo-L-thyronine)
  • L-TYROSINE, O-(4-HYDROXYPHENYL)-3,5-DIIODO-O-(4-HYDROXYPHENYL)-3,5-DIIODO-L-TYROSINE diiodothyronine
  • TIANFU CHEM-- 3,5-Diiodo-L-thyronine
  • Liothyronine Sodium EP Impurity E
  • 3,5-Diiodo-L-thyronine 1041-01-6 CAS NO.1041-01-6
  • Levothyroxine Sodium EP Impurity E
  • Liothyronine Sodium Impurity E
  • NSC 90469 (Levothyroxine Impurity)
  • LEVOTHYROXINE EP IMPURITY E | DIIOTHYRONINE
  • 1041-01-6
  • C15H13I2NO4
  • Modified Amino Acids
  • Biochemicals and Reagents
  • BioChemical
  • A - H
  • Amino Acids and Peptides
  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives
  • Intermediates
  • Labeling and Diagnostics Reagents
  • Medicine intermediate