COCHLIOQUINONE A
- Product Name
- COCHLIOQUINONE A
- CAS No.
- 32450-25-2
- Chemical Name
- COCHLIOQUINONE A
- Synonyms
- Luteoleersin;Cochlioquinone;Coclioquinone A;COCHLIOQUINONE A;(3R)-9-[(1S,2R,3S)-2-Acetyloxy-1,3-dimethylpentyl]-1,2,3,4aβ,5,6,6a,12,12aβ,12b-decahydro-12β-hydroxy-3α-(1-hydroxy-1-methylethyl)-6aα,12bα-dimethylpyrano[3,2-a]xanthene-8,11-dione;(2S,3R,4S)-2-[(3R,4aR,6aR,12S,12bR)-12-hydroxy-3-(2-hydroxypropan-2-yl)-6a,12b-dimethyl-8,11-dioxo-1,2,3,4a,5,6,12,12a-octahydropyrano[3,2-a]xanthen-9-yl]-4-methylhexan-3-yl] acetate;Pyrano[3,2-a]xanthene-8,11-dione, 9-[(1S,2R,3S)-2-(acetyloxy)-1,3-dimethylpentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethyl-, (3R,4aR,6aR,12S,12aS,12bR)-
- CBNumber
- CB0286529
- Molecular Formula
- C30H44O8
- Formula Weight
- 532.67
- MOL File
- 32450-25-2.mol
COCHLIOQUINONE A Property
- Melting point:
- 135 °C
- Boiling point:
- 638.8±55.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A yellow lyophilisate
- pka
- 11.57±0.70(Predicted)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 19440
- Product name
- Cochlioquinone A
- Purity
- ≥99%
- Packaging
- 500μg
- Price
- $291
- Updated
- 2024/03/01
- Product number
- 19440
- Product name
- Cochlioquinone A
- Purity
- ≥99%
- Packaging
- 2.5mg
- Price
- $1160
- Updated
- 2024/03/01
- Product number
- C633560
- Product name
- CochlioquinoneA
- Packaging
- 500μg
- Price
- $245
- Updated
- 2021/12/16
- Product number
- 1051CB
- Product name
- CochlioquinoneA
- Packaging
- 2.5mg
- Price
- $1390
- Updated
- 2021/12/16
- Product number
- MTB0000899
- Product name
- COCHLIOQUINONE-A
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.63
- Updated
- 2021/12/16
COCHLIOQUINONE A Chemical Properties,Usage,Production
Uses
Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. Cochlioquinone A has recently been shown to be an antagonist of the human chemokine receptor, CCR5, in HIV-1,). Cochlioquinone A is anti-angiogenic and exhibits inhibitory activity against diacylglycerol acyltransferase and NADH-ubiquinone reductase.
Uses
Cochlioquinone A, a bioactive compound isolated from D. sacchari and Bipolaris sp., is an inhibitor of diacylglycerol kinase (DGK; Ki = 3.1 μM) and diacylglycerol acyltransferase (DGAT; IC50 = 5.6 μM). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma with an IC50 value of 3 μM. It is also reported to compete with macrophage inflammatory protein-1α for binding to human CCR5 chemokine receptors with an IC50 value of 11 μM.[Cayman Chemical]
Uses
Cochlioquinone A is an antagonist of CCR5. Diacylglycerol kinase inhibitor.
Definition
ChEBI: Cochlioquinone A is a member of oxanes.
COCHLIOQUINONE A Preparation Products And Raw materials
Raw materials
Preparation Products
COCHLIOQUINONE A Suppliers
- Tel
- --
- Fax
- --
- sales21@chemicalland21.com
- Country
- South Korea
- ProdList
- 6303
- Advantage
- 74