ChemicalBook > CAS DataBase List > Tiamulin fumarate

Tiamulin fumarate

Product Name: Tiamulin fumarate
CAS No.: 55297-96-6
Chemical Name: Tiamulin fumarate
Synonyms: TIAMULIN HYDROGEN FUMARATE;Tiamuline Hydrogen Fumarate;DENAGARD;TIAMULIN FUMERATE;((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE;sq22947;STAMULIN;81723hfu;dynamutilin;sandoz81723hfu
CBNumber: CB0294038
Molecular Formula: C32H51NO8S
Formula Weight: 609.82
MOL File: 55297-96-6.mol

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Tiamulin fumarate Property

Melting point:: 147-148°C
Boiling point:: 563℃
Flash point:: >110°(230°F)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
color: White
Water Solubility: Soluble in water
Merck: 13,9495
InChI: InChI=1/C28H47NO4S.C4H4O4/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28;5-3(6)1-2-4(7)8/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t19-,20+,22-,24+,25+,26-,27?,28?;/s3
InChIKey: YXQXDXAHCSEVSD-IHAONTCTSA-N
SMILES: C(/C(=O)O)=C\C(=O)O.C[C@H]1[C@@H]([C@](C[C@@H](OC(=O)CSCCN(CC)CC)C2([C@H](C)CCC31CCC(=O)[C@]32[H])C)(C)C=C)O |&1:9,10,11,13,27,36,r|
CAS DataBase Reference: 55297-96-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36
RIDADR: UN2811 6.1/PG 3
WGK Germany: 3
RTECS: AG9560000
HS Code: 29419090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000414
Product name: Tiamulin for peak identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 10 mg
Price: $225
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0000333
Product name: Tiamulin hydrogen fumarate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 500 mg
Price: $225
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR2721
Product name: Tiamulin fumarate
Purity: Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500?mg
Packaging: 500MG
Price: $259
Updated: 2025/07/31

Sigma-Aldrich

Product number: 46959
Product name: Tiamulin fumarate
Purity: VETRANAL?, analytical standard
Packaging: 100mg
Price: $55.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1667290
Product name: Tiamulin fumarate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 250mg
Price: $467
Updated: 2025/07/31

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Tiamulin fumarate Chemical Properties,Usage,Production

Chemical Properties

White Solid. soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide.

Uses

Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis. It is a derivative of Pleuromutilin with Antibacterial that targets Gram-positive bacteria as well as a few mycoplasma species.

Application

Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity. The hemi-fumarate provides a stable salt with improved water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action of inhibiting protein synthesis by binding to domain V of 23S rRNA.

Indications

Tiamulin fumarate is mainly used for Mycoplasma suis pneumonia, Haemophilus parasuis, infectious pleuropneumonia and dysentery caused by Treponema swine, and also for chronic respiratory tract of poultry, Mycoplasma pneumonia, infectious rhinitis, Escherichia coli, duck Infectious serositis.

Health Hazard

Inhalation may irritate (cough, short breathing, difficulty in breathing). Headache. It may cause moderate irritation, including a burning sensation, tearing, redness, or swelling. Itching. Causes serious eye irritation. Redness, itching, tears. Stinging. It may cause irritation to the digestive tract. Abdominal pain, nausea.

Mode of action

Tiamulin fumarate is a bacteriostatic antibiotic belonging to the pleuromutilin class, which inhibit protein synthesis by targeting the 50S bacterial ribosomal subunit and binding to peptidyl transferase, the enzyme responsible for forming peptide bonds between amino acids.

Tiamulin fumarate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tiamulin fumarate Suppliers

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View Lastest Price from Tiamulin fumarate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Tiamulin fumarate 55297-96-6
Price: US $0.00/Kg/Drum
Min. Order: 25KG
Purity: 97%-102%; USP
Supply Ability: 1000KGS
Release date: 2021-07-19

Hebei Chuanghai Biotechnology Co., Ltd

Product: Tiamulin fumarate 55297-96-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-15

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: Tiamulin fumarate 55297-96-6
Price: US $1000.00-700.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-14

55297-96-6, Tiamulin fumarateRelated Search:

Rotundine Ketotifen fumarate Tiamulin Ethylparaben CHLOROPHOSPHONAZO III Ethyl 2-(Chlorosulfonyl)acetate Fumaric acid Ethanol Dimethyl fumarate Ferrous fumarate Pleuromulin Ethyl acetate Telithromycin Tulathromycin A Tylosin Acetic anhydride Phenylacetic acid ISOOCTYL THIOGLYCOLATE

((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE

sq22947

ter,(e)-2-butenedioate(1:1)(salt)

thiamutilinfumarate

STAMULIN

TIAMULIN FUMARATE

TIAMULIN FUMERATE

TIAMULIN HYDROGEN FUMARATE

TIAMULIN FUMARATE VETRANAL, 100 MG

Acetic acid, 2-(diethylamino)ethylthio-, (3aS,4R,5S,6S,8R,9S,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, (2E)-2-butenedioate (1:1) (salt)

[[2-(Diethylamino)ethyl]thio]-acetic acid 6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester (E)-2-butenedioate

Tiamulin Fumarate (250 mg)

TiaMulin FuMarate USP USP

Tiamulin hydrogen famarate

TyMulina hydrogen fuMarate

TiaMulin FuMarate (80%,98%)

-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-

Taimiomycin fumarate

5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl 2-((2-(diethylamino)ethyl)thio)acetate but-2-enedioate

DENAGARD

,10-tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles

14-deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate

14-desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato

81723hfu

dynamutilin

sandoz81723hfu

Tiamuline Hydrogen Fumarate

Tiamulin fumer

Tiamulin Fumarate Usp

(89708-74-7) tiamulin fumarate

Tiamulin hydrogen fumarate CRS

Tiamulin fumarate USP/EP/BP

5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a

80% tiamulin hydrogen fumarate

API Tiamulin Fumarate Hydrogen CAS 55297-96-6 Raw Material

Tiamulin Hydrogen fumarateQ: What is Tiamulin Hydrogen fumarate Q: What is the CAS Number of Tiamulin Hydrogen fumarate Q: What is the storage condition of Tiamulin Hydrogen fumarate Q: What are the applications of Tiamulin Hydrogen fumarate

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55297-96-6

5297-96-6

C28H47NO4SC4H4O4

C32H51NO8S

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