Tiamulin
- Product Name
- Tiamulin
- CAS No.
- 55297-95-5
- Chemical Name
- Tiamulin
- Synonyms
- TIAMILIN;tiamulina;TiaMulin fuMerate API;(3aS,4R,5S,6S,8R,9R,9aR,10R)-Decahydro-8-[[2-(diethylamino)ethyl]thio]acetyloxy-5-hydroxy-4,6,9,10-tetramethyl-6-vinyl-3a,9-propano-3aH-cyclopentacycloocten-1-one;C12065;sq14055;tiavetp;iamulin;TIAMULIN;Tiamutin
- CBNumber
- CB7171536
- Molecular Formula
- C28H47NO4S
- Formula Weight
- 493.74
- MOL File
- 55297-95-5.mol
Tiamulin Property
- Melting point:
- 147.5°C
- Boiling point:
- 563.0±50.0 °C(Predicted)
- Density
- 1.0160 (rough estimate)
- refractive index
- 1.6550 (estimate)
- storage temp.
- -20°C Freezer
- solubility
- Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
- pka
- 14.65±0.70(Predicted)
- color
- Colourless
- CAS DataBase Reference
- 55297-95-5(CAS DataBase Reference)
- EPA Substance Registry System
- Tiamulin (55297-95-5)
Safety
- WGK Germany
- 2
- RTECS
- AG9552000
- HS Code
- 2941906000
- Hazardous Substances Data
- 55297-95-5(Hazardous Substances Data)
N-Bromosuccinimide Price
- Product number
- 34044
- Product name
- Tiamulin
- Purity
- VETRANAL?, analytical standard
- Packaging
- 100MG
- Price
- $274
- Updated
- 2024/03/01
- Product number
- 1667355
- Product name
- Tiamulin
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 100mg
- Price
- $436
- Updated
- 2024/03/01
- Product number
- T436595
- Product name
- Tiamulin
- Packaging
- 100mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 286986
- Product name
- 5-Hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl hydroxyacetate
- Packaging
- 10g
- Price
- $333
- Updated
- 2021/12/16
- Product number
- I023
- Product name
- Tiamulin
- Packaging
- 100mg
- Price
- $314
- Updated
- 2021/12/16
Tiamulin Chemical Properties,Usage,Production
Uses
Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity and an ionisable group for salt formation and greater water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Like pleuromutilin, it inhibits protein synthesis by binding to domain V of 23S rRNA.
Uses
Tiamulin is a derivative of Pleuromutilin. Antibacterial.
Definition
ChEBI: A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) fo the treatment of swine dysentery caused by Serpulina hyodysenteriae.
General Description
Tiamulin has been developed by that company in collaboration with E.R. Squibb & Sons for use against animal infec tions. Tiamulin is used against dysentery and Mycoplasma infections in sheep, swine, cattle, and chickens.
Safety Profile
Poison by intramuscular and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of SOx and NOx. See also MERCAPTANS.
Synthesis
Tiamulin was synthesized by Sandoz Co. in 1973, starting from pleuromutilin produced by Pleurotus mutilus.
Veterinary Drugs and Treatments
Tiamulin is approved for use in swine to treat pneumonia caused by susceptible strains of Haemophilus pleuropneumoniae and swine dysentery caused by Treponema hyodysenteriae. As a feed additive, it is used to cause increased weight gain in swine.
Tiamulin Preparation Products And Raw materials
Raw materials
Preparation Products
Tiamulin Suppliers
- Tel
- 18702759083
- 1038369936@qq.com
- Country
- China
- ProdList
- 280
- Advantage
- 58
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- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
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- China
- ProdList
- 11726
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9823
- Advantage
- 79
- Tel
- 0871-65217109 13211707573;
- Fax
- 0871-65215563
- y.liu@mail.biobiopha.com
- Country
- China
- ProdList
- 5654
- Advantage
- 65
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4941
- Advantage
- 60
- Tel
- 010-56205725
- Fax
- 010-65763397
- waley188@sohu.com
- Country
- China
- ProdList
- 12338
- Advantage
- 58
- Tel
- 86 592 2680277
- Fax
- 0086 592 2680237
- sale@simagchem.com
- Country
- China
- ProdList
- 430
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- 55
- Tel
- 18521735133 18521732826;
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25015
- Advantage
- 65
- Tel
- 025-57798810
- Fax
- 025-57019371
- sales@sunlidabio.com
- Country
- China
- ProdList
- 3750
- Advantage
- 55
- Tel
- 021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7934
- Advantage
- 58
View Lastest Price from Tiamulin manufacturers
- Product
- Tiamulin 55297-95-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg
- Release date
- 2024-03-25
- Product
- Tiamulin hyclate 55297-95-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 ton
- Release date
- 2021-06-25
- Product
- Tiamulin 55297-95-5
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-11-04