Tiamulin fumarate

Product Name: Tiamulin fumarate
CAS No.: 55297-96-6
Chemical Name: Tiamulin fumarate
Synonyms: TIAMULIN HYDROGEN FUMARATE;Tiamuline Hydrogen Fumarate;DENAGARD;TIAMULIN FUMERATE;((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE;sq22947;STAMULIN;81723hfu;dynamutilin;sandoz81723hfu
CBNumber: CB0294038
Molecular Formula: C32H51NO8S
Formula Weight: 609.82
MOL File: 55297-96-6.mol

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Tiamulin fumarate Property

Melting point:: 147-148°C
Boiling point:: 563℃
Flash point:: >110°(230°F)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
color: White
Water Solubility: Soluble in water
Merck: 13,9495
InChI: InChI=1/C28H47NO4S.C4H4O4/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28;5-3(6)1-2-4(7)8/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t19-,20+,22-,24+,25+,26-,27?,28?;/s3
InChIKey: YXQXDXAHCSEVSD-IHAONTCTSA-N
SMILES: C(/C(=O)O)=C\C(=O)O.C[C@H]1[C@@H]([C@](C[C@@H](OC(=O)CSCCN(CC)CC)C2([C@H](C)CCC31CCC(=O)[C@]32[H])C)(C)C=C)O |&1:9,10,11,13,27,36,r|
CAS DataBase Reference: 55297-96-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36
RIDADR: UN2811 6.1/PG 3
WGK Germany: 3
RTECS: AG9560000
HS Code: 29419090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2721
Product name: Tiamulin fumarate
Purity: Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 500?mg
Packaging: 500MG
Price: $241
Updated: 2024/03/01

Sigma-Aldrich

Product number: 46959
Product name: Tiamulin fumarate
Purity: VETRANAL?, analytical standard
Packaging: 100mg
Price: $54.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1667290
Product name: Tiamulin fumarate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 250mg
Price: $436
Updated: 2024/03/01

Alfa Aesar

Product number: J66020
Product name: Tiamulin fumarate
Purity: 95%
Packaging: 500mg
Price: $274
Updated: 2024/03/01

Alfa Aesar

Product number: J66020
Product name: Tiamulin fumarate
Purity: 95%
Packaging: 100mg
Price: $55.5
Updated: 2023/06/20

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Tiamulin fumarate Chemical Properties,Usage,Production

Chemical Properties

White Solid. soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide.

Uses

Tiamulin fumarate is a semisynthetic pleuromutilin antibiotic that binds to the ribosomal peptidyl transferase centre and inhibits protein synthesis. It is a derivative of Pleuromutilin with Antibacterial that targets Gram-positive bacteria as well as a few mycoplasma species.

Application

Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity. The hemi-fumarate provides a stable salt with improved water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action of inhibiting protein synthesis by binding to domain V of 23S rRNA.

Indications

Tiamulin fumarate is mainly used for Mycoplasma suis pneumonia, Haemophilus parasuis, infectious pleuropneumonia and dysentery caused by Treponema swine, and also for chronic respiratory tract of poultry, Mycoplasma pneumonia, infectious rhinitis, Escherichia coli, duck Infectious serositis.

Health Hazard

Inhalation may irritate (cough, short breathing, difficulty in breathing). Headache. It may cause moderate irritation, including a burning sensation, tearing, redness, or swelling. Itching. Causes serious eye irritation. Redness, itching, tears. Stinging. It may cause irritation to the digestive tract. Abdominal pain, nausea.

Mode of action

Tiamulin fumarate is a bacteriostatic antibiotic belonging to the pleuromutilin class, which inhibit protein synthesis by targeting the 50S bacterial ribosomal subunit and binding to peptidyl transferase, the enzyme responsible for forming peptide bonds between amino acids.

Tiamulin fumarate Preparation Products And Raw materials

Raw materials

Preparation Products

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Tiamulin fumarate Suppliers

Australia 1 Belgium 1 Brazil 1 Canada 2 China 317 Czech Republic 1 France 1 Germany 10 India 10 Japan 1 Malaysia 1 Mexico 1 Philippines 1 Poland 1 Singapore 1 South Korea 1 Spain 2 Switzerland 2 The Netherlands 2 United Kingdom 12 United States 31 Global 400

Shandong Jihao Biotechnology Co., Ltd.

Tel: 0531-69958659 15668363232
Email: 8598038@qq.com
Country: China
ProdList: 45
Advantage: 58

Wuhan Dingxintong Pharmaceutical Co. , Ltd.

Tel: 027-027-83984790 17720532645
Fax: 027-83984790
Email: t17720532645@163.com
Country: China
ProdList: 971
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8836
Advantage: 52

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2866
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

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View Lastest Price from Tiamulin fumarate manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: Tiamulin fumarate 55297-96-6
Price: US $1000.00-700.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-14

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Tiamulin Fumarate 55297-96-6
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-12-04

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Tiamulin Dydrogen fumarate 55297-96-6
Price: US $0.00/kg
Min. Order: 25kg
Purity: 99%
Supply Ability: 10tons
Release date: 2024-04-24

55297-96-6, Tiamulin fumarateRelated Search:

Rotundine Ketotifen fumarate Tiamulin Ethylparaben CHLOROPHOSPHONAZO III Ethyl 2-(Chlorosulfonyl)acetate Fumaric acid Ethanol Dimethyl fumarate Ferrous fumarate Pleuromulin Ethyl acetate Telithromycin Tulathromycin A Tylosin Acetic anhydride Phenylacetic acid ISOOCTYL THIOGLYCOLATE

((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE

sq22947

ter,(e)-2-butenedioate(1:1)(salt)

thiamutilinfumarate

STAMULIN

TIAMULIN FUMARATE

TIAMULIN FUMERATE

TIAMULIN HYDROGEN FUMARATE

TIAMULIN FUMARATE VETRANAL, 100 MG

Acetic acid, 2-(diethylamino)ethylthio-, (3aS,4R,5S,6S,8R,9S,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, (2E)-2-butenedioate (1:1) (salt)

[[2-(Diethylamino)ethyl]thio]-acetic acid 6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester (E)-2-butenedioate

Tiamulin Fumarate (250 mg)

TiaMulin FuMarate USP USP

Tiamulin hydrogen famarate

TyMulina hydrogen fuMarate

TiaMulin FuMarate (80%,98%)

-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-

Taimiomycin fumarate

5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl 2-((2-(diethylamino)ethyl)thio)acetate but-2-enedioate

DENAGARD

,10-tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles

14-deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate

14-desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato

81723hfu

dynamutilin

sandoz81723hfu

Tiamuline Hydrogen Fumarate

Tiamulin fumer

Tiamulin Fumarate Usp

(89708-74-7) tiamulin fumarate

Tiamulin hydrogen fumarate CRS

Tiamulin fumarate USP/EP/BP

5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a

80% tiamulin hydrogen fumarate

API Tiamulin Fumarate Hydrogen CAS 55297-96-6 Raw Material

Tiamulin Hydrogen fumarateQ: What is Tiamulin Hydrogen fumarate Q: What is the CAS Number of Tiamulin Hydrogen fumarate Q: What is the storage condition of Tiamulin Hydrogen fumarate Q: What are the applications of Tiamulin Hydrogen fumarate

TIANFU-CHEM CAS:55297-96-6 Tiamulin fumarate

Tiamulin Fumarate (1667290)

Fumarate tymitin

Tymectin fumarate

80%Tiamulin fumarate

Tiamulin Dydrogen fumarate

Yanhusuo acid Taimiaocin

Tiamulin hydrogen famarate98%

C17575800 Tiamulin fumerate

Tylvalosin succinate

55297-96-6

5297-96-6

C28H47NO4SC4H4O4

C32H51NO8S

Amines

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds

API