Sodium octanoate Property

Melting point:

~245 °C (dec.)

Density 

1.188 at 20℃

vapor pressure 

0Pa at 20℃

storage temp. 

Inert atmosphere,Room Temperature

solubility 

H₂O: 50 mg/mL, clear

form 

Powder

color 

White to off-white

Odor

Characteristic

PH

8.0-10.5 (100g/l, H2O, 20°C)

Water Solubility 

soluble

BRN 

3597723

Stability:

Stable. Incompatible with strong oxidizing agents.

LogP

0.106 at 23.9℃ and pH7-7.95

Surface tension

69.8mN/m at 1g/L and 20℃

CAS DataBase Reference

1984-06-1(CAS DataBase Reference)

EPA Substance Registry System

Sodium octanoate (1984-06-1)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

37/39-26

WGK Germany 

3

RTECS 

RH0787000

TSCA 

Yes

HS Code 

29156000

Hazardous Substances Data

1984-06-1(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: > 2000 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

Sodium octanoate Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

Excipient.

Uses

Sodium octanoate is the sodium salt of caprylic acid. It functions as a binder, emulsifier, and anticaking agent.

Uses

Sodium octanoate may be used as a protein stabilizer for molecules such as albumin and fibrinogen under conditions such heat sterilization. Also used for blood plasma fractionation.

Definition

ChEBI: Sodium octanoate is an organic sodium salt comprising equal numbers of sodium and octanoate ions. It contains an octanoate.

Application

Sodium octanoate has a wide range of uses. It is used as a lubricant or release agent in the food industry, and as a drug solvent in the pharmaceutical field.Rectal infusion of Sodium octanoate can increase the average bioavailability of cefoxitin and promote the absorption of cefoxitin in the rectum of the human body. In the chemical industry, it can be used as solubilising agent or raw material for organic synthesis. When the concentration of octanoate is low, the addition of neutral salt can increase the solubilising capacity of decanol^[1-2].

Clinical Use

Sodium caprylate is prepared from caprylic acid, which is acomponent of coconut and palm oils. The salt precipitates ascream-colored granules that are soluble in water and sparinglysoluble in alcohol.
Sodium caprylate is used topically to treat superficialdermatomycoses caused by C. albicans and Trichophyton,Microsporum, and Epidermophyton spp. The sodium saltcan be purchased in solution, powder, and ointment forms.

References

[1] EJ VAN HOOGDALEM. Rate-controlled rectal absorption enhancement of cefoxitin by co- administration of sodium salicylate or sodium octanoate in healthy volunteers.[J]. British journal of clinical pharmacology, 1989. DOI:10.1111/j.1365-2125.1989.tb05337.x.
[2] PER EKWALL; Krister F; Leo Mandell. The effect of sodium chloride on the solubilization of decan-1-ol in sodium octanoate solutions and the formation of mesophases[J]. Journal of Colloid and Interface Science, 1977. DOI:10.1016/0021-9797(77)90470-2.