7-METHOXY-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE
- Product Name
- 7-METHOXY-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE
- CAS No.
- 1810-74-8
- Chemical Name
- 7-METHOXY-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE
- Synonyms
- 7-METHOXY-2;4-TRIMETHYL-1;ASISCHEM Y53008;AKOS BBS-00005636;2-DIHYDROQUINOLINE;7-methoxy-2,2,4-trimethyl-1H-quinoline;2,2,4-Trimethyl-7-methoxy-1,2-dihydroquinoline;7-METHOXY-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE;1,2-Dihydro-7-Methoxy-2,2,4-triMethylquinoline;Quinoline, 1,2-dihydro-7-Methoxy-2,2,4-triMethyl-
- CBNumber
- CB0298551
- Molecular Formula
- C13H17NO
- Formula Weight
- 203.28
- MOL File
- Mol file
7-METHOXY-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE Property
- Melting point:
- 67-69℃
- Boiling point:
- 306℃
- Density
- 0.986
- Flash point:
- 125℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 3.83±0.70(Predicted)
- color
- Beige to Very Dark Beige
- InChI
- InChI=1S/C13H17NO/c1-9-8-13(2,3)14-12-7-10(15-4)5-6-11(9)12/h5-8,14H,1-4H3
- InChIKey
- VNIQAUZZZWOJPT-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC(OC)=C2)C(C)=CC1(C)C
- CAS DataBase Reference
- 1810-74-8
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M271100
- Product name
- 7-Methoxy-2,2,4-trimethyl-1,2-dihydroquinoline
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- M271100
- Product name
- 7-Methoxy-2,2,4-trimethyl-1,2-dihydroquinoline
- Packaging
- 1g
- Price
- $990
- Updated
- 2021/12/16
- Product number
- 143904
- Product name
- 7-Methoxy-2,2,4-trimethyl-1,2-dihydroquinoline
- Purity
- 95%
- Packaging
- 5g
- Price
- $1444
- Updated
- 2021/12/16
- Product number
- 143904
- Product name
- 7-Methoxy-2,2,4-trimethyl-1,2-dihydroquinoline
- Purity
- 95%
- Packaging
- 25g
- Price
- $3886
- Updated
- 2021/12/16
- Product number
- W3936
- Product name
- 7-Methoxy-2,2,4-trimethyl-1,2-dihydroquinoline
- Packaging
- 5g
- Price
- $171
- Updated
- 2021/12/16
7-METHOXY-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE Chemical Properties,Usage,Production
Uses
7-Methoxy-2,2,4-trimethyl-1,2-dihydroquinoline is a 1,2-dihydroquinoline derivative with antiinflammatory activity. IT is used in the preparation of fluorescent dyes biological microscopy and nanoscopy.
Synthesis
141-79-7
536-90-3
1810-74-8
Under stirring conditions, m-aminoanisole (26 mL, 0.23 mol) was slowly added dropwise to acetic acid (2.6 mL), followed by the slow addition of 4-methyl-3-penten-2-one (27 mL, 0.23 mol). The reaction mixture was stirred at room temperature overnight and then concentrated hydrobromic acid (50 mL) was added. After continued stirring for 1 h, the precipitate was collected by filtration and washed with acetone. The resulting solid was dissolved in water (100 mL) and the pH was adjusted to 7 with 10 N aqueous sodium hydroxide.The aqueous phase was extracted with chloroform (3 x 50 mL), the organic phases were combined and dried over anhydrous sodium sulfate. After filtration to remove sodium sulfate, the filtrate was concentrated in vacuum to give the crude product. The crude product was recrystallized from hexane to give 7-methoxy-2,2,4-trimethyl-1,2-dihydroquinoline (15.5 g, 33% yield) as a pale yellow solid.
References
[1] New Journal of Chemistry, 2016, vol. 40, # 6, p. 4888 - 4890
[2] Patent: US2013/89853, 2013, A1. Location in patent: Paragraph 0087
[3] Patent: US2016/289779, 2016, A1. Location in patent: Paragraph 0060
7-METHOXY-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-METHOXY-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE manufacturers
- Product
- 7-METHOXY-2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE 1810-74-8
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-08