ChemicalBook > CAS DataBase List > (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

Product Name
(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
CAS No.
1012341-54-6
Chemical Name
(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
Synonyms
LCZ704;LCZ696-18;LCZ696696-A-C;LCZ696 impuritiesF;LCZ-696 Impurity 18;LCZ 696 Impurity F;LCZ-696 Impurity 35;LCZ696 impurities126;Sacubitril Impurity 1;Sacubitril Impurity F
CBNumber
CB02995775
Molecular Formula
C23H29NO4
Formula Weight
383.48
MOL File
1012341-54-6.mol
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(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Property

Boiling point:
582.6±50.0 °C(Predicted)
Density 
1.115±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
4+-.0.23(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1/C23H29NO4/c1-16(21(25)26)14-20(24-22(27)28-23(2,3)4)15-17-10-12-19(13-11-17)18-8-6-5-7-9-18/h5-13,16,20H,14-15H2,1-4H3,(H,24,27)(H,25,26)/t16-,20+/s3
InChIKey
YNELJETWNMPEEH-OXDNQSQGNA-N
SMILES
C(O)(=O)[C@@H](C)C[C@@H](NC(OC(C)(C)C)=O)CC1=CC=C(C2=CC=CC=C2)C=C1 |&1:3,6,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D463585
Product name
(αS,​γR)​-γ-​[[(1,​1-​Dimethylethoxy)​carbonyl]​amino]​-​α-​methyl-​[1,​1''-​biphenyl]​-​4-​pentanoicAcid
Packaging
10mg
Price
$525
Updated
2021/12/16
Crysdot
Product number
CD21019728
Product name
(2S,4R)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoicacid
Purity
97%
Packaging
25mg
Price
$972
Updated
2021/12/16
Crysdot
Product number
CD21019728
Product name
(2S,4R)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoicacid
Purity
97%
Packaging
50mg
Price
$1736
Updated
2021/12/16
Crysdot
Product number
CD21019728
Product name
(2S,4R)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoicacid
Purity
97%
Packaging
5mg
Price
$228
Updated
2021/12/16
Crysdot
Product number
CD21019728
Product name
(2S,4R)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoicacid
Purity
97%
Packaging
10mg
Price
$416
Updated
2021/12/16
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(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Chemical Properties,Usage,Production

Uses

(αS,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1''-biphenyl]-4-pentanoic Acid is a useful synthetic intermediate.

(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Suppliers

China 60 India 3 United States 5 Global 68
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
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3001379618@qq.com
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China
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Adamas Reagent, Ltd.
Tel
400-6009262 15618770481
Fax
021-64823266
Email
yhx@titansci.com
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China
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Jiangsu Vcare PharmaTech Co., Ltd.
Tel
025-58741518 13327700685
Fax
+86-25-58744115
Email
sales@vcarepharmatech.com
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China
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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0755-4000505016 13380397412
Fax
0755 28094224
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3001272453@qq.com
Country
China
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Changzhou Renaissance Chem Co. Ltd
Tel
86-519-86202821
Fax
Email： sales@rosewellchem.com
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China
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Quality Control Solutions Ltd.
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0755-66853366 13670046396
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
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sales@reading-chemicals.com
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China
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Suzhou PengXu PharmaTech Co., Ltd.
Tel
15850786624
Email
sales@cqpharm.com
Country
China
ProdList
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BOC Sciences
Tel
16314854226
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info@bocsci.com
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United States
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Roark Standards
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0755-83552066 15986688328
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0755-83552066
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1012341-54-6, (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acidRelated Search:

Sacubitril Impurity 10 LCZ Impurity AHU-377 Sacubitril Impurity 72 LCZ696 LCZ696 interMediate (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid sacubitril (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid AHU-377 (heMicalciuM salt) Valsartan (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

  • (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
  • LCZ 696 Impurity F
  • (αS,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1-biphenyl]-4-pentanoic Acid
  • Sacubitril Impurity F
  • LCZ704
  • (2S,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid
  • LCZ696696-A-C
  • LCZ-696 Impurity 18
  • Sacubitril Impurity 1
  • LCZ-696 Impurity 35
  • LCZ696-18
  • LCZ696(valsartan + sacubitril) impurity 19
  • 1,1'-Biphenyl]-4-pentanoic acid, γ-[[(1,1-dimethylethoxy)carbonyl]amino]-α-methyl-, (αS,γR)-
  • -?[[(1,?1-?Dimethylethoxy)?carbonyl]?amino]?-?&alpha
  • -?biphenyl]?-?4-?pentanoicAcid
  • -?methyl-?[1,?1&rsquo
  • (αS,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl[1,1'-biphenyl]-4-pentanoic acid
  • LCZ696 impurities126
  • LCZ696 impuritiesF
  • LCZ-696 Impurity 18(S,R)
  • LCZ696 valsartan + sacubitril impurity 17
  • Sabatrol calcium impurity 3
  • (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid（Sacubitril Impurity FB）
  • 1012341-54-6
  • LCZ696