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Erlotinib D6 HCl

Product Name
Erlotinib D6 HCl
CAS No.
1189953-78-3
Chemical Name
Erlotinib D6 HCl
Synonyms
Erlotinib D6;OSI-774 D6 hydrochloride;Erlotiniβ-d6 Hydrochloride;CP-358774 D6 hydrochloride;NSC 718781 D6 hydrochloride;[2H6]-Erlotinib Hydrochloride;Erlotinib Hydrochloride Impurity G
CBNumber
CB03049808
Molecular Formula
C22H18ClD6N3O4
Formula Weight
435.933630668
MOL File
1189953-78-3.mol
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Erlotinib D6 HCl Property

storage temp. 
Store at -20°C
solubility 
DMSO: slightly, heated,Methanol: slightly soluble
form 
A solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22101
Product name
Erlotinib-d6 (hydrochloride)
Purity
≥99% deuterated forms (d1-d6)
Packaging
1mg
Price
$279
Updated
2024/03/01
TRC
Product number
E625002
Product name
Erlotinib-d6Hydrochloride
Packaging
1mg
Price
$145
Updated
2021/12/16
AK Scientific
Product number
7728DG
Product name
ErlotinibD6Hydrochloride
Packaging
1mg
Price
$409
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
RDL0006809
Product name
ERLOTINIB-D6-HYDROCHLORIDE
Purity
95.00%
Packaging
10MG
Price
$1871.1
Updated
2021/12/16
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Erlotinib D6 HCl Chemical Properties,Usage,Production

Description

Erlotinib-d6 (hydrochloride) contains six deuterium atoms located on the methoxy group. It is intended for use as an internal standard for the quantification of erlotinib by GC- or LC-MS. Erlotinib is a tyrosine kinase inhibitor that acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 μM) and JAK2 mutant JAK2V617F (IC50 = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. Formulations containing erlotinib are used to treat certain forms of cancer, including non-small cell lung cancer.

Uses

Erlotinib D6 HCl is a Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, Antineoplastic.;Labeled Erlotinib, intended for use as an internal standard for the quantification of Erlotinib by GC- or LC-mass spectrometry.

Erlotinib D6 HCl Preparation Products And Raw materials

Raw materials

Preparation Products

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Erlotinib D6 HCl Suppliers

Canada 1 China 27 India 4 United States 6 Global 38
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7189
Advantage
65
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18044
Advantage
56
Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2965
Advantage
58
Clearsynth Canada Inc.
Tel
+1.415.685.4395
Fax
+1.415.685.4395
Email
enquiry@clearsynth.com
Country
Canada
ProdList
912
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9577
Advantage
60
Chengdu Novel Biomedical Co., Ltd.
Tel
028-85255396 18302801538
Fax
028-85255396
Email
cdnovell@163.com
Country
China
ProdList
2304
Advantage
58
Shanghai ring qi biological technology co., LTD
Tel
13524106587
Email
sales@hq-chem.com
Country
China
ProdList
225
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
56604
Advantage
58
Shenzhen Botel Biotechnology Co. Ltd.
Tel
0755-22202135 13316968096
Email
1979313431@qq.com
Country
China
ProdList
8814
Advantage
58

1189953-78-3, Erlotinib D6 HClRelated Search:

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  • Erlotinib D6
  • Erlotinib Hydrochloride Impurity G
  • [2H6]-Erlotinib Hydrochloride
  • CP-358774 D6 hydrochloride
  • NSC 718781 D6 hydrochloride
  • OSI-774 D6 hydrochloride
  • Erlotiniβ-d6 Hydrochloride
  • 1189953-78-3