ChemicalBook > CAS DataBase List > Hydroxy-PEG3-Mes

Hydroxy-PEG3-Mes

Product Name: Hydroxy-PEG3-Mes
CAS No.: 139115-89-2
Chemical Name: Hydroxy-PEG3-Mes
Synonyms: Ms-peg4;CAS_139115-89-2;Hydroxy-PEG3-MS;Hydroxy-PEG3-Mes;3,6,9-Trioxa-2-thiaundecan-11-ol, 2,2-dioxide;2-(2-(2-Hydroxyethoxy)ethoxy)ethyl methanesulfonate
CBNumber: CB03050772
Molecular Formula: C7H16O6S
Formula Weight: 228.26
MOL File: 139115-89-2.mol

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Hydroxy-PEG3-Mes Property

Boiling point:: 398.2±27.0 °C(Predicted)
Density: 1.256±0.06 g/cm3(Predicted)
pka: 14.36±0.10(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-20704
Product name: Ms-PEG4
Purity: 98%
Packaging: 1g
Price: $240
Updated: 2021/12/16

BroadPharm

Product number: BP-21102
Product name: Hydroxy-PEG3-Ms
Purity: 90%
Packaging: 1g
Price: $240
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: POL0002506
Product name: MS-PEG4
Purity: 95.00%
Packaging: 1G
Price: $420
Updated: 2021/12/16

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Hydroxy-PEG3-Mes Chemical Properties,Usage,Production

Uses

Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Hydroxy-PEG3-Mes Preparation Products And Raw materials

Raw materials

Preparation Products

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139115-89-2, Hydroxy-PEG3-MesRelated Search:

Mes-PEG5- t-butyl ester Mes-PEG5- THP Mes-PEG2-acid t-butyl ester Hydroxy-PEG14-t-butly ester 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid PEG4-acid Hydroxy-PEG7-t-butyl acetate Hydroxy-PEG5-t-butyl acetate PEG8-t-butly ester PEG14-t-butly ester

Hydroxy-PEG3-Mes

Hydroxy-PEG3-MS

Ms-peg4

CAS_139115-89-2

3,6,9-Trioxa-2-thiaundecan-11-ol, 2,2-dioxide

2-(2-(2-Hydroxyethoxy)ethoxy)ethyl methanesulfonate

139115-89-2

C7H16O6S