ChemicalBook > CAS DataBase List > Azido-PEG10-acid

Azido-PEG10-acid

Product Name: Azido-PEG10-acid
CAS No.: 1644163-57-4
Chemical Name: Azido-PEG10-acid
Synonyms: N3-PEG10-COOH;Azido-PEG11-acid;Azido-PEG10-acid;Azido-PEG10-tBu Ester;1-Azido-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid;N3-PEG10-CH2CH2COOH/Propanoic acid, 3-[(29-azido-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)oxy]-
CBNumber: CB03062335
Molecular Formula: C23H45N3O12
Formula Weight: 555.62
MOL File: 1644163-57-4.mol

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Azido-PEG10-acid Property

solubility: Soluble in Water, DMSO, DMF

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Safety

HS Code: 2918999090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-21820
Product name: Azido-PEG10-acid
Purity: 98%
Packaging: 100mg
Price: $240
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1111
Product name: Azido-PEG10-acid
Packaging: 100mg
Price: $795
Updated: 2021/12/16

purepeg

Product number: 437710
Product name: N3-PEG10-CH2CH2COOH
Purity: min.95%
Packaging: 250mg
Price: $265
Updated: 2021/12/16

Acrotein

Product number: B-0903
Product name: N3-PEG10-CH2CH2COOH
Purity: 97%
Packaging: 0.25g
Price: $302.5
Updated: 2021/12/16

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Azido-PEG10-acid Chemical Properties,Usage,Production

Description

Azido-PEG10-acid is a water soluble PEG compound containing an azide group with a terminal carboxylic acid. The azide (N3) group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Azido-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG10-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG10-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Azido-PEG10-acid manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: 1-azido-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid 1644163-57-4
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

Xian confluore Biological Technology Co., Ltd.

Product: azido-PEG10-Acid 1644163-57-4
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

1644163-57-4, Azido-PEG10-acidRelated Search:

N3-PEG10-Tos Azido-PEG16-acid O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)NONAETHYLENE GLYCOL Azido-PEG10-NHBoc Azido-PEG11-amine Ethyl acetate Azido-PEG10-azide Azido-PEG13-azide Azido-PEG9-t-butyl ester Azido-PEG10-alcohol Azido-PEG13-alcohol Azido-PEG9-acid N3-PEGn-OH 2K, 5K, 10K, 20K Azido-PEG11-alcohol Azido-PEG12-acid Azido-PEG10-Br Azido-PEG10-hydrazide Azido-PEG11-NHBoc

Azido-PEG10-acid

Azido-PEG11-acid

N3-PEG10-COOH

Azido-PEG10-tBu Ester

N3-PEG10-CH2CH2COOH/Propanoic acid, 3-[(29-azido-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)oxy]-

1-Azido-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid

1644163-57-4

C23H45N3O12

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