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Huperzine A

Product Name
Huperzine A
CAS No.
120786-18-7
Chemical Name
Huperzine A
Synonyms
SELAGINE;HUPERAZINE A;HUPERZINE A;[+/-]-SELAGINE;(+/-)-SELAGINE;(+/-)-HuperzineA;(+/-)-HUPERZINE A;(+/-)-HUPERAZINE A;(±)-Huperzine A, >98%;Huperzine A USP/EP/BP
CBNumber
CB0308078
Molecular Formula
C15H18N2O
Formula Weight
242.32
MOL File
120786-18-7.mol
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Huperzine A Property

Boiling point:
505.0±50.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO : ≥ 50 mg/mL (206.34 mM)
form 
Off-white solid.
pka
12.25±0.60(Predicted)
InChI
InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+
InChIKey
ZRJBHWIHUMBLCN-QDEBKDIKSA-N
SMILES
C12CC3/C(=C\C)/C(N)(C=1C=CC(=O)N2)CC(C)=C3
CAS DataBase Reference
120786-18-7
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25-36/37/38
Safety Statements 
26-36/37/39-45
RIDADR 
UN 1544 6.1/PG 2
WGK Germany 
3
RTECS 
PB9185700
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H5777
Product name
(±)-Huperzine A
Purity
synthetic, ≥98% (TLC)
Packaging
1mg
Price
$269
Updated
2024/03/01
TRC
Product number
H826003
Product name
(+/-)-HuperzineA
Packaging
5mg
Price
$65
Updated
2021/12/16
TRC
Product number
H826003
Product name
(+/-)-HuperzineA
Packaging
10mg
Price
$110
Updated
2021/12/16
TRC
Product number
H826003
Product name
(+/-)-HuperzineA
Packaging
25mg
Price
$200
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594012
Product name
Huperzine A
Packaging
20mg
Price
$238
Updated
2021/12/16
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Huperzine A Chemical Properties,Usage,Production

Description

Huperzine A is an alkaloid extract derived from the Chinese club moss Huperzia serrata. It is an acetylcholinesterase inhibitor. This means it helps promote higher levels of acetylcholine in the brain. Higher levels of acetylcholine support ones ability to perform cognitive tasks such as learning new things, memorizing information, and focusing at the task at hand. Huperzine A is considered to be a nootropic supplement because it supports cognitive function. It is considered a focus and memory nootropic similar to alpha gpc, bacopa, phosphatidylcholine, cdp choline, sulbutiamine, and uridine. It is also considered a brain booster as it is used for brain health and support.
Huperzine A for many years has been widely used in traditional Chinese medicine to enhance memory and to treat fever and inflammation. In the United States it is commercially available as a food supplement, but has not been approved by the FDA as a treatment for AD or other cognition disorders.

Occurrence

Huperzine A is a synthetic.

Uses

Huperzine A is used for dementia in Alzheimer’s disease and for muscle weakness in myasthenia gravis.

Uses

(+/-)-Huperzine A is an NMDA antagonist.

Application

(±)-Huperzine A has been used in anti-acetylcholinesterase bioautographic assay.

benefits

Huperzine A can help support learning and memory by protecting acetylcholine, a neurotransmitter that acts as a messenger molecule in the brain. Huperzine A may be used for both short-term "brain boost" needs, such as preparing for a test, as well as more long-term needs, such as reducing the mild memory loss associated with normal aging.
ACETYLCHOLINESTERASE INHIBITOR - Huperzine A acts as a reversible Acetylcholinesterase inhibitor meaning it supports levels of the neurotransmitter acetylcholine which plays a key role in cognitive function.
SUPPORTS COGNITIVE FUNCTION - Supports working memory, motivation, and problem solving ability.
SUPPORTS ENERGY AND STAMINA - Huperzine A supports mental energy, stamina, and sustained focus.

Biological Activity

Huperzine A is an effective acetylcholinesterase inhibitor and can cross the blood-brain barrier. Huperzine A is known to prevent cognitive defects, glutamate-induced nerve cell death.It is recognized for its use in the treatment of Alzheimer′s disease and organophosphate poisoning.

Side effects

When taken at recommended doses Huperzine A is well tolerated and presents few side effects. Rarely, side effects including nausea, diarrhea, and loss of appetite may occur. Adverse side effects are more likely when exceeding the recommended dosage.
Huperzine A is not recommended for people suffering from heart conditions, consult your physician before taking this product.

Dosage forms

Huperzine A supplementation tends to be in the range of 50 - 200 mcg daily. Our tablets are 200 mcg each, but can be easily broken into halves or quarters for those wishing to take smaller doses.
Huperzine A has a long half-life (10-14 hours), so cycling this product is often recommended. We recommend taking it no more than 2-3 times per week, or if using it daily we recommend taking a 1 week break for every 2 weeks of use.

Huperzine A Preparation Products And Raw materials

Raw materials

Preparation Products

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Huperzine A Suppliers

Jiangsu Huayu Chemical Co., Ltd.
Tel
25-83241163
Fax
+86-25-83241173
Email
sales@elegantnutri.com
Country
China
ProdList
55
Advantage
55
Chengdu Chenlv Herb Co., Ltd.
Tel
028-88523492 15528171243
Email
chenrongpharma@126.com
Country
China
ProdList
124
Advantage
58
Shaanxi Pioneer Biotech Co., Ltd
Tel
029-86621125 18123784671
Email
sales@pioneerbiotech.com
Country
China
ProdList
500
Advantage
58
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.
Tel
18858184290; 18858184290
Fax
0086-571-28313105
Email
sales@zyterpharm.com
Country
China
ProdList
48
Advantage
49
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
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View Lastest Price from Huperzine A manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Huperzine A 120786-18-7
Price
US $0.00/G
Min. Order
1G
Purity
98%min
Supply Ability
30KG/month
Release date
2023-01-31
Wuhan Nutra Biotechnology Co.,Ltd
Product
Huperzine A 120786-18-7
Price
US $150.00-0.00/g
Min. Order
1g
Purity
1% 98%+
Supply Ability
100kgs
Release date
2021-05-24
Hebei Chuanghai Biotechnology Co,.LTD
Product
Selagine 120786-18-7
Price
US $10.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-08

120786-18-7, Huperzine ARelated Search:


  • (+/-)-SELAGINE
  • [+/-]-SELAGINE
  • SELAGINE
  • (11E)-5-Amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2(1H)-one
  • (±)-Huperzine A, >98%
  • 1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one
  • (+/-)-HUPERAZINE A
  • HUPERAZINE A
  • (+/-)-HUPERZINE A
  • HUPERZINE A
  • ((plusmn))-Huperzine A
  • Huperzia Serrata Extract (Standard)
  • 5,9-Methanocycloocta[b]pyridin-2(1H)-one, 5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (11E)-
  • (+/-)-HuperzineA
  • Huperzine A USP/EP/BP
  • (±)-Huperzine A solution
  • (E)-5-amino-11-ethylidene-7-methyl-5,6,9,10-tetrahydro-5,9-methanocycloocta[b]pyridin-2(1H)-one
  • Cholinesterase (ChE),inhibit,Inhibitor,(±)-Huperzine A,(±) Huperzine A,(±)Huperzine A
  • 120786-18-7
  • Cholinesterase, acetyl
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Enzyme
  • Enzymes, Inhibitors, and Substrates
  • A to C
  • Biochemicals and Reagents
  • BioChemical
  • Herb extract
  • Natural Plant Extract
  • Acetylcholine receptor