ChemicalBook > CAS DataBase List > Huperzine A

Huperzine A

Product Name: Huperzine A
CAS No.: 120786-18-7
Chemical Name: Huperzine A
Synonyms: SELAGINE;HUPERAZINE A;HUPERZINE A;[+/-]-SELAGINE;(+/-)-SELAGINE;(±)-Huperzine A;(+/-)-HuperzineA;(+/-)-HUPERZINE A;(+/-)-HUPERAZINE A;(±)-Huperzine A, >98%
CBNumber: CB0308078
Molecular Formula: C15H18N2O
Formula Weight: 242.32
MOL File: 120786-18-7.mol

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Huperzine A Property

Boiling point:: 505.0±50.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO : ≥ 50 mg/mL (206.34 mM)
form: Off-white solid.
pka: 12.25±0.60(Predicted)
InChI: InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+
InChIKey: ZRJBHWIHUMBLCN-QDEBKDIKSA-N
SMILES: C12CC3/C(=C\C)/C(N)(C=1C=CC(=O)N2)CC(C)=C3
CAS DataBase Reference: 120786-18-7

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Safety

Hazard Codes: T
Risk Statements: 23/24/25-36/37/38
Safety Statements: 26-36/37/39-45
RIDADR: UN 1544 6.1/PG 2
WGK Germany: 3
RTECS: PB9185700

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H5777
Product name: (±)-Huperzine A
Purity: synthetic, ≥98% (TLC)
Packaging: 1mg
Price: $235
Updated: 2025/07/31

TRC

Product number: H826003
Product name: (+/-)-HuperzineA
Packaging: 5mg
Price: $65
Updated: 2021/12/16

TRC

Product number: H826003
Product name: (+/-)-HuperzineA
Packaging: 10mg
Price: $110
Updated: 2021/12/16

TRC

Product number: H826003
Product name: (+/-)-HuperzineA
Packaging: 25mg
Price: $200
Updated: 2021/12/16

ChemScene

Product number: CS-1089
Product name: (±)-Huperzine A
Purity: ≥98.0%
Packaging: 10mg
Price: $114
Updated: 2021/12/16

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Huperzine A Chemical Properties,Usage,Production

Description

Huperzine A is an alkaloid extract derived from the Chinese club moss Huperzia serrata. It is an acetylcholinesterase inhibitor. This means it helps promote higher levels of acetylcholine in the brain. Higher levels of acetylcholine support ones ability to perform cognitive tasks such as learning new things, memorizing information, and focusing at the task at hand. Huperzine A is considered to be a nootropic supplement because it supports cognitive function. It is considered a focus and memory nootropic similar to alpha gpc, bacopa, phosphatidylcholine, cdp choline, sulbutiamine, and uridine. It is also considered a brain booster as it is used for brain health and support.
Huperzine A for many years has been widely used in traditional Chinese medicine to enhance memory and to treat fever and inflammation. In the United States it is commercially available as a food supplement, but has not been approved by the FDA as a treatment for AD or other cognition disorders.

Occurrence

Huperzine A is a synthetic.

Uses

Huperzine A is used for dementia in Alzheimer’s disease and for muscle weakness in myasthenia gravis.

Uses

(+/-)-Huperzine A is an NMDA antagonist.

Application

(±)-Huperzine A has been used in anti-acetylcholinesterase bioautographic assay.

benefits

Huperzine A can help support learning and memory by protecting acetylcholine, a neurotransmitter that acts as a messenger molecule in the brain. Huperzine A may be used for both short-term "brain boost" needs, such as preparing for a test, as well as more long-term needs, such as reducing the mild memory loss associated with normal aging.
ACETYLCHOLINESTERASE INHIBITOR - Huperzine A acts as a reversible Acetylcholinesterase inhibitor meaning it supports levels of the neurotransmitter acetylcholine which plays a key role in cognitive function.
SUPPORTS COGNITIVE FUNCTION - Supports working memory, motivation, and problem solving ability.
SUPPORTS ENERGY AND STAMINA - Huperzine A supports mental energy, stamina, and sustained focus.

Biological Activity

Huperzine A is an effective acetylcholinesterase inhibitor and can cross the blood-brain barrier. Huperzine A is known to prevent cognitive defects, glutamate-induced nerve cell death.It is recognized for its use in the treatment of Alzheimer′s disease and organophosphate poisoning.

Side effects

When taken at recommended doses Huperzine A is well tolerated and presents few side effects. Rarely, side effects including nausea, diarrhea, and loss of appetite may occur. Adverse side effects are more likely when exceeding the recommended dosage.
Huperzine A is not recommended for people suffering from heart conditions, consult your physician before taking this product.

Dosage forms

Huperzine A supplementation tends to be in the range of 50 - 200 mcg daily. Our tablets are 200 mcg each, but can be easily broken into halves or quarters for those wishing to take smaller doses.
Huperzine A has a long half-life (10-14 hours), so cycling this product is often recommended. We recommend taking it no more than 2-3 times per week, or if using it daily we recommend taking a 1 week break for every 2 weeks of use.

Huperzine A Preparation Products And Raw materials

Raw materials

Preparation Products

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Huperzine A Suppliers

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View Lastest Price from Huperzine A manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Huperzine A 120786-18-7
Price: US $0.00/G
Min. Order: 1G
Purity: 98%min
Supply Ability: 30KG/month
Release date: 2023-01-31

Shaanxi Xianhe Biotech Co., Ltd

Product: Huperzine A 120786-18-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000kg
Release date: 2025-04-15

Wuhan Nutra Biotechnology Co.,Ltd

Product: Huperzine A 120786-18-7
Price: US $150.00-0.00/g
Min. Order: 1g
Purity: 1% 98%+
Supply Ability: 100kgs
Release date: 2021-05-24

120786-18-7, Huperzine ARelated Search:

Matrine Ursolic acid D-(-)-Salicin 4-(N-[3-CHLOROPHENYL]-CARBAMOYLOXY)-2-BUTYNYLTRIMETHYLAMMONIUM CHLORIDE Galantamine Hydrobromide 6-[5-[(2S)-2-AZETIDINYLMETHOXY]-3-PYRIDINYL]-5-HEXYN-1-OL DIHYDROCHLORIDE 2-(3-PYRIDINYL)PIPERIDINE HYDROCHLORIDE (-)-HUPERZINE A, 99% HPLC,(-)-Huperzine A,Huperzine A ( Selagine ),(-)-HUPERZINE A FROM HUPERZIA SERRATA,Huperzine-A1-5%,HUPERZINE A 1% HUPERZINE Huperzine A (-)-HUPERZINE A, HUPERZIA SERRATA +/- HUPERZINE MW= 242.3 Huperzine Serrate P.E. HUPERZINE-A,CRUDE HUPERZINE B HUPERZINE-A,PURE HUPERZINE A WHITE POWDER

(+/-)-SELAGINE

[+/-]-SELAGINE

SELAGINE

(11E)-5-Amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2(1H)-one

(±)-Huperzine A, >98%

1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one

(+/-)-HUPERAZINE A

HUPERAZINE A

(+/-)-HUPERZINE A

HUPERZINE A

((plusmn))-Huperzine A

Huperzia Serrata Extract (Standard)

5,9-Methanocycloocta[b]pyridin-2(1H)-one, 5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (11E)-

(+/-)-HuperzineA

Huperzine A USP/EP/BP

(±)-Huperzine A solution

(E)-5-amino-11-ethylidene-7-methyl-5,6,9,10-tetrahydro-5,9-methanocycloocta[b]pyridin-2(1H)-one

Cholinesterase (ChE),inhibit,Inhibitor,(±)-Huperzine A,(±) Huperzine A,(±)Huperzine A

(±)-Huperzine A, 10 mM in DMSO

(±)-Huperzine A

120786-18-7

Cholinesterase, acetyl

Enzyme Inhibitors

Enzyme Inhibitors by Enzyme

Enzymes, Inhibitors, and Substrates

A to C

Biochemicals and Reagents

BioChemical

Herb extract

Natural Plant Extract

Acetylcholine receptor