ChemicalBook > CAS DataBase List > WEHI-345 (analog)
WEHI-345 (analog)
- Product Name
- WEHI-345 (analog)
- CAS No.
- 1354825-62-9
- Chemical Name
- WEHI-345 (analog)
- Synonyms
- WEHI-345 alog;WEHI-345 analogue;WEHI-345 (analog);Reaxys ID: 22174618;WEHI 345 analog,WEHI345 analog;2-Pyridinecarboxamide, N-[2-[4-amino-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-2-methylpropyl]-3-methyl-
- CBNumber
- CB03122352
- Molecular Formula
- C23H25N7O
- Formula Weight
- 415.49
- MOL File
- 1354825-62-9.mol
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WEHI-345 (analog) Property
- Boiling point:
- 688.0±55.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : ≥ 30 mg/mL (72.20 mM)
- form
- Solid
- pka
- 12.67±0.46(Predicted)
- color
- White to gray
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N-Bromosuccinimide Price
Biorbyt Ltd
- Product number
- orb611430
- Product name
- WEHI-345 analog
- Packaging
- 5mg
- Price
- $569.5
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611430
- Product name
- WEHI-345 analog
- Packaging
- 10mg
- Price
- $615.4
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611430
- Product name
- WEHI-345 analog
- Packaging
- 25mg
- Price
- $1208.7
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31003763
- Product name
- WEHI-345analog
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $243
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31003763
- Product name
- WEHI-345analog
- Purity
- 98+%
- Packaging
- 10mg
- Price
- $347
- Updated
- 2021/12/16
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WEHI-345 (analog) Chemical Properties,Usage,Production
Uses
WEHI-345 analog is the analog of WEHI-345. WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation[1].
IC 50
RIPK2
References
[1] Nachbur U, et al. A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production. Nat Commun. 2015 Mar 17;6:6442. DOI:10.1038/ncomms7442
WEHI-345 (analog) Preparation Products And Raw materials
Raw materials
Preparation Products
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WEHI-345 (analog) Suppliers
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1354825-62-9, WEHI-345 (analog)Related Search:
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