ChemicalBook > CAS DataBase List > Methyl lactate

Methyl lactate

Product Name
Methyl lactate
CAS No.
547-64-8
Chemical Name
Methyl lactate
Synonyms
Methyl 2-hydroxypropanoate;LACTIC ACID METHYL ESTER;METHYL LACTATE;lactatedemethyle;MethylLactate>METHYL DL-LACTATE;DL-METHYL LACTATE;Lactic acid methyl;Milchsremethylester;Methyl lactate (DL)
CBNumber
CB0312448
Molecular Formula
C4H8O3
Formula Weight
104.1
MOL File
547-64-8.mol
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Methyl lactate Property

Melting point:
-66°C
Boiling point:
35 °C (6 mmHg)
alpha 
[α]D20+1.410~+1.418
Density 
1.093 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.413
Flash point:
49 °C
storage temp. 
Flammables area
form 
Liquid
pka
13.07±0.20(Predicted)
color 
Clear colorless to pale yellow
Specific Gravity
1.09
Water Solubility 
miscible, hydrolyses
Sensitive 
Moisture Sensitive
Merck 
14,6094
BRN 
1720586
InChIKey
LPEKGGXMPWTOCB-UHFFFAOYSA-N
LogP
-0.670 (est)
CAS DataBase Reference
547-64-8(CAS DataBase Reference)
NIST Chemistry Reference
Propanoic acid, 2-hydroxy-, methyl ester(547-64-8)
EPA Substance Registry System
Methyl lactate (547-64-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
10-36/37
Safety Statements 
24-24/25
RIDADR 
UN 3272 3/PG 3
WGK Germany 
1
RTECS 
OD5670000
21
TSCA 
Yes
HazardClass 
3.2
PackingGroup 
III
HS Code 
29181100
Hazardous Substances Data
547-64-8(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
69822
Product name
Methyl DL-lactate
Purity
≥97.0% (GC)
Packaging
5ml
Price
$80.6
Updated
2024/03/01
Sigma-Aldrich
Product number
69822
Product name
Methyl DL-lactate
Purity
≥97.0% (GC)
Packaging
25ml
Price
$245
Updated
2024/03/01
TCI Chemical
Product number
L0004
Product name
Methyl Lactate
Purity
>98.0%(GC)
Packaging
25mL
Price
$47
Updated
2024/03/01
TCI Chemical
Product number
L0004
Product name
Methyl Lactate
Purity
>98.0%(GC)
Packaging
500mL
Price
$177
Updated
2024/03/01
Alfa Aesar
Product number
H60455
Product name
Methyl DL-lactate, 99%
Packaging
5ml
Price
$62.65
Updated
2024/03/01
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Methyl lactate Chemical Properties,Usage,Production

Description

Methyl lactate is a compound with many uses. It can be used as a solvent, as a starting material for the manufacture of polyiactic acid, or as a starting material for numerous other reactions. For example, it can be used as intermediate in lactic acid purification, and as building block in the synthesis of chiral components, e.g., pesticides, and as a starting material for lactide manufacture.

Chemical Properties

Methyl lactate is a colorless transparent liquid. It is soluble/miscible in water, acetone, ethyl alcohol, and other organic solvents. It is used as a cellulose acetate solvent.

Uses

Methyl lactate is used as a solvent for nitrocellulose, cellulase acetate, cellulase acetobutyrote and cellulase acetaprapionate. It is used in the manufacture of lacquers and dopes where it contributes high tolerance for diluents, good flaw and blush resistance.

Application

One important use of methyl lactate is use in the manufacture of methyl acrylate, which is a starting material for the manufacture of acrylate polymers. Additionally methyl acrylate is a suitable starting material for acrylic acid and other esters like ethyl acrylate and butyl acrylate.

Preparation

Bringing an aqueous liquid comprising lactic acid, methanol, and at least 5 wt.% of a dissolved chloride salt selected from magnesium chloride, calcium chloride, and zinc chloride to reaction conditions, thereby obtaining methyl lactate, wherein an extractant is provided to the reaction mixture before, during, and/or after formation of methyl lactate,Subjecting the reaction mixture to a liquid-liquid separation step wherein an organic phase comprising methyl lactate and extractant is separated from an aqueous phase comprising dissolved chloride salt.The wt.% is calculated on the weight of the aqueous liquid. It has been found that the process according to the invention makes it possible to manufacture methyl lactate efficiently and in high yield. 

Definition

ChEBI: Methyl lactate is a lactate ester resulting from the formal condensation of the carboxy group of 2-hydroxypropanoic acid with methanol. It has a role as a metabolite. It is a lactate ester and a methyl ester.

Hazard

Moderate fire risk.

Safety Profile

Methyl lactate has been classed as non-irritant to the eyes of guinea pigs.
The estimated average lethal dose for the female rat following i.p. injection of methyl lactate was >2000 mg/kg body weight. Observations included narcosis, respiratory distress and peritoneal adhesions. The estimated non toxic dose and estimated maximum dose without gross lesions at necropsy was 500 mg/kg body weight.

Synthesis

Methyl lactate is prepared by the esterification of methyl alcohol with lactic acid.

Purification Methods

Methyl lactate is easily hydrolyzed and often contains impurities such as free lactic acid, methanol and water. Free acid can be removed by washing after neutralization with alkali. Moisture can be removed by azeotropic distillation of an azeotropic mixture with benzene. Then, it was purified by distillation under reduced pressure. Since calcium chloride and the like form molecular compounds with methyl lactate, they cannot be used as desiccants. When the methyl lactate is mixed with water, it can be extracted and recovered with benzene, ether, etc.

Methyl lactate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl lactate Suppliers

Aladdin Scientific
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+1-+1(833)-552-7181
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United States
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Brown Chemical Co., Inc.
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United States Biological
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HONEST JOY HOLDINGS LIMITED
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View Lastest Price from Methyl lactate manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
Methyl lactate 547-64-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-03
Qingdao RENAS Polymer Material Co., Ltd.
Product
Methyl lactate 547-64-8
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2024-08-21
Hebei Weibang Biotechnology Co., Ltd
Product
Methyl lactate 547-64-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-11

547-64-8, Methyl lactateRelated Search:


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  • 2-HYDROXYPROPANOIC ACID METHYL ESTER
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  • 547-64-8
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