MK-2 Inhibitor III

Product Name: MK-2 Inhibitor III
CAS No.: 1186648-22-5
Chemical Name: MK-2 Inhibitor III
Synonyms: MK2-IN-3 hydrate;MK-2 Inhibitor III;MK-2 INHIBITOR III (COMPOUND 16);MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem;2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one:hydrate;2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate;Inhibitor,MAP kinase activated protein kinase 2,inhibit,MK2 IN 3 hydrate,MAPKAP kinase 2,MK-2-IN-3 hydrate,MAPK activated protein kinase 2,MK2IN3 hydrate,MAPKAPK2 (MK2),Mitogen-activated protein kinase activated protein kinase 2
CBNumber: CB03136757
Molecular Formula: C21H18N4O2
Formula Weight: 358.4
MOL File: 1186648-22-5.mol

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MK-2 Inhibitor III Property

Melting point:: >255°C (dec.)
storage temp.: +2C to +8C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Pale yellow solid
color: Off-White to Pale Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 15943
Product name: MK2 Inhibitor III
Purity: ≥95%
Packaging: 500μg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 15943
Product name: MK2 Inhibitor III
Purity: ≥95%
Packaging: 1mg
Price: $110
Updated: 2024/03/01

Cayman Chemical

Product number: 15943
Product name: MK2 Inhibitor III
Purity: ≥95%
Packaging: 5mg
Price: $225
Updated: 2024/03/01

AK Scientific

Product number: 3003DC
Product name: MK-2InhibitorIII
Packaging: 5mg
Price: $348
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 47746
Product name: MK2InhibitorIII
Packaging: 2.5mg
Price: $625
Updated: 2021/12/16

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MK-2 Inhibitor III Chemical Properties,Usage,Production

Description

MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation. MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC₅₀ = 8.5 nM). It less potently blocks MK3 and MK5 (IC₅₀s = 210 and 81 nM, respectively) and is weak or inactive against several other kinases, including other p38 MAP kinase targets. MK2 inhibitor III prevents LPS-induced synthesis of TNF-α in human monocyte-like U937 cells (IC₅₀ = 4.4 μM).

Uses

MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation. MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC50 = 8.5 nM). It less potently blocks MK3 and MK5 (IC50s = 210 and 81 nM, respectively) and is weak or inactive against several other kinases, including other p38 MAP kinase targets. MK2 inhibitor III prevents LPS-induced synthesis of TNF-α in human monocyte-like U937 cells (IC50 = 4.4 μM).[Cayman Chemical]

MK-2 Inhibitor III Preparation Products And Raw materials

Raw materials

Preparation Products

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MK-2 Inhibitor III Suppliers

China 45 India 1 United States 8 Global 54

Tianjin Kailiqi Biotechnology Co., Ltd.

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1186648-22-5, MK-2 Inhibitor IIIRelated Search:

MK-2 Inhibitor III

2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one:hydrate

MK-2 INHIBITOR III (COMPOUND 16)

MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem

MK2-IN-3 hydrate

2-(2-(Quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one hydrate

Inhibitor,MAP kinase activated protein kinase 2,inhibit,MK2 IN 3 hydrate,MAPKAP kinase 2,MK-2-IN-3 hydrate,MAPK activated protein kinase 2,MK2IN3 hydrate,MAPKAPK2 (MK2),Mitogen-activated protein kinase activated protein kinase 2

1186648-22-5