ChemicalBook > CAS DataBase List > FGF-401

FGF-401

Product Name
FGF-401
CAS No.
1708971-55-4
Chemical Name
FGF-401
Synonyms
Roblitinib;0997;FGF-401;FGF 401;FGF-401;FGF401( Roblitinib);Roblitinib（FGF-401）;FGF-401 ISO 9001：2015 REACH;8-naphthyridine-1(2H)-carboxamide;N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide;N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
CBNumber
CB03166185
Molecular Formula
C25H30N8O4
Formula Weight
506.56
MOL File
1708971-55-4.mol
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FGF-401 Property

Boiling point:
852.1±65.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:5.4(Max Conc. mg/mL);10.66(Max Conc. mM)
Chloroform:30.0(Max Conc. mg/mL);59.22(Max Conc. mM)
form 
A crystalline solid
pka
11.40±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23029
Product name
FGF401
Packaging
1mg
Price
$33
Updated
2023/01/06
Cayman Chemical
Product number
23029
Product name
FGF401
Packaging
5mg
Price
$147
Updated
2023/01/06
Cayman Chemical
Product number
23029
Product name
FGF401
Packaging
10mg
Price
$260
Updated
2023/01/06
Cayman Chemical
Product number
23029
Product name
FGF401
Packaging
25mg
Price
$568
Updated
2023/01/06
ChemScene
Product number
CS-6853
Product name
Roblitinib
Purity
99.33%
Packaging
50mg
Price
$690
Updated
2021/12/16
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FGF-401 Chemical Properties,Usage,Production

Description

FGF401 is an inhibitor of FGF receptor 4 (FGFR4; IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also decreases serum cholesterol when administered at doses ranging from 5 to 45 mg/kg per day.

FGF-401 Preparation Products And Raw materials

Raw materials

Preparation Products

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FGF-401 Suppliers

China 87 United States 5 Global 92
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View Lastest Price from FGF-401 manufacturers

Career Henan Chemical Co
Product
8-naphthyridine-1(2H)-carboxamide 1708971-55-4
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2019-12-25

1708971-55-4, FGF-401Related Search:

4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester Roxadustat BEZ235 (NVP-BEZ235, Dactolisib)

  • N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
  • N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
  • Roblitinib（FGF-401）
  • FGF 401;FGF-401
  • 8-naphthyridine-1(2H)-carboxamide
  • 0997
  • N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide
  • Roblitinib
  • 1,8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-
  • FGF-401
  • FGF401( Roblitinib)
  • FGF-401 ISO 9001：2015 REACH
  • 1708971-55-4
  • API