FGF-401

ChemicalBook > CAS DataBase List > FGF-401

Product Name: FGF-401
CAS No.: 1708971-55-4
Chemical Name: FGF-401
Synonyms: Roblitinib;0997;FGF-401;FGF 401;FGF-401;FGF401( Roblitinib);Roblitinib（FGF-401）;FGF-401 ISO 9001：2015 REACH;8-naphthyridine-1(2H)-carboxamide;N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide;N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
CBNumber: CB03166185
Molecular Formula: C25H30N8O4
Formula Weight: 506.56
MOL File: 1708971-55-4.mol

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FGF-401 Property

Boiling point:: 852.1±65.0 °C(Predicted)
Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:5.4(Max Conc. mg/mL);10.66(Max Conc. mM)
Chloroform:30.0(Max Conc. mg/mL);59.22(Max Conc. mM)
form: A crystalline solid
pka: 11.40±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23029
Product name: FGF401
Packaging: 1mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 23029
Product name: FGF401
Packaging: 5mg
Price: $166
Updated: 2024/03/01

Cayman Chemical

Product number: 23029
Product name: FGF401
Packaging: 10mg
Price: $292
Updated: 2024/03/01

Cayman Chemical

Product number: 23029
Product name: FGF401
Packaging: 25mg
Price: $638
Updated: 2024/03/01

ChemScene

Product number: CS-6853
Product name: Roblitinib
Purity: 99.33%
Packaging: 50mg
Price: $690
Updated: 2021/12/16

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FGF-401 Chemical Properties,Usage,Production

Description

FGF401 is an inhibitor of FGF receptor 4 (FGFR4; IC₅₀ = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC₅₀ value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also decreases serum cholesterol when administered at doses ranging from 5 to 45 mg/kg per day.

FGF-401 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from FGF-401 manufacturers

Career Henan Chemical Co

Product: 8-naphthyridine-1(2H)-carboxamide 1708971-55-4
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2019-12-25

1708971-55-4, FGF-401Related Search:

Roxadustat 4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester BEZ235 (NVP-BEZ235, Dactolisib)

N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide

N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide

Roblitinib（FGF-401）

FGF 401;FGF-401

8-naphthyridine-1(2H)-carboxamide

0997

N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide

Roblitinib

1,8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-

FGF-401

FGF401( Roblitinib)

FGF-401 ISO 9001：2015 REACH

N-{5-cyano-4-[(2-methoxyethyl)amino]pyridin-2-yl}-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxamide

1708971-55-4

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