ChemicalBook > CAS DataBase List > FGF-401

FGF-401

Product Name
FGF-401
CAS No.
1708971-55-4
Chemical Name
FGF-401
Synonyms
Roblitinib;0997;FGF-401;FGF 401;FGF-401;FGF401( Roblitinib);Roblitinib（FGF-401）;FGF-401 ISO 9001：2015 REACH;8-naphthyridine-1(2H)-carboxamide;N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide;N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
CBNumber
CB03166185
Molecular Formula
C25H30N8O4
Formula Weight
506.56
MOL File
1708971-55-4.mol
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FGF-401 Property

Boiling point:
852.1±65.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:5.4(Max Conc. mg/mL);10.66(Max Conc. mM)
Chloroform:30.0(Max Conc. mg/mL);59.22(Max Conc. mM)
form 
A crystalline solid
pka
11.40±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23029
Product name
FGF401
Packaging
1mg
Price
$38
Updated
2024/03/01
Cayman Chemical
Product number
23029
Product name
FGF401
Packaging
5mg
Price
$166
Updated
2024/03/01
Cayman Chemical
Product number
23029
Product name
FGF401
Packaging
10mg
Price
$292
Updated
2024/03/01
Cayman Chemical
Product number
23029
Product name
FGF401
Packaging
25mg
Price
$638
Updated
2024/03/01
ChemScene
Product number
CS-6853
Product name
Roblitinib
Purity
99.33%
Packaging
50mg
Price
$690
Updated
2021/12/16
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FGF-401 Chemical Properties,Usage,Production

Description

FGF401 is an inhibitor of FGF receptor 4 (FGFR4; IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also decreases serum cholesterol when administered at doses ranging from 5 to 45 mg/kg per day.

FGF-401 Preparation Products And Raw materials

Raw materials

Preparation Products

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FGF-401 Suppliers

China 99 United States 5 USA 1 Global 105
Shanghai Synchem Pharma Co., ltd
Tel
021-61984905-1 18016477331
Email
synchempharma@aliyun.com
Country
China
ProdList
6451
Advantage
55
Shanghai Dongyang Biotechnology Co., Ltd.
Tel
0512-0512-13601744364 13601744364
Email
chemsharker@126.com
Country
China
ProdList
878
Advantage
58
Kaixin Chemical (Hong Kong) Limited
Tel
010-88886666-01 13112345678
Fax
CDXH21@126.com
Email
loyson@tcypharm.com
Country
China
ProdList
595
Advantage
55
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9552
Advantage
66
Shanghai Feibo Chemical Technology Co., Ltd
Tel
021-58955608,2250286 15921236618
Email
blinkzeng@gmail.com
Country
China
ProdList
523
Advantage
62
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3419
Advantage
58
Changzhou Renaissance Chem Co. Ltd
Tel
86-519-86202821
Fax
Email： sales@rosewellchem.com
Country
China
ProdList
116
Advantage
56
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View Lastest Price from FGF-401 manufacturers

Career Henan Chemical Co
Product
8-naphthyridine-1(2H)-carboxamide 1708971-55-4
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2019-12-25

1708971-55-4, FGF-401Related Search:

Roxadustat 4-[3-Oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]piperazine-1-carboxylic acid 3,5-dichlorobenzyl ester BEZ235 (NVP-BEZ235, Dactolisib)

  • N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
  • N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2~{H}-1,8-naphthyridine-1-carboxamide
  • Roblitinib（FGF-401）
  • FGF 401;FGF-401
  • 8-naphthyridine-1(2H)-carboxamide
  • 0997
  • N-[5-Cyano-4-[(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-1,8-naphthyridine-1(2H)-carboxamide
  • Roblitinib
  • 1,8-Naphthyridine-1(2H)-carboxamide, N-[5-cyano-4-(2-methoxyethyl)amino]-2-pyridinyl]-7-formyl-3,4-dihydro-6-[(4-methyl-2-oxo-1-piperazinyl)methyl]-
  • FGF-401
  • FGF401( Roblitinib)
  • FGF-401 ISO 9001：2015 REACH
  • N-{5-cyano-4-[(2-methoxyethyl)amino]pyridin-2-yl}-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxamide
  • 1708971-55-4
  • API