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PHOSPHORAMIDON

Product Name
PHOSPHORAMIDON
CAS No.
36357-77-4
Chemical Name
PHOSPHORAMIDON
Synonyms
eucyl)-;yptophan;PHOSPHORAMIDON;PHOSPHORAMIDON SODIUM SALT;PHOSPHORAMIDON DISODIUM SALT DIHYDRATE;N-(A-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP-OH;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP 2NA;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP SODIUM SALT;N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN
CBNumber
CB0324672
Molecular Formula
C23H34N3O10P
Formula Weight
543.51
MOL File
36357-77-4.mol
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PHOSPHORAMIDON Property

Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: 1 mM Stock solution stable for 1 month at –20° C.
pka
-0.66±0.50(Predicted)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
10-21
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Hazard and Precautionary Statements (GHS)

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PHOSPHORAMIDON Chemical Properties,Usage,Production

Definition

ChEBI: A dipeptide isolated from the cultures of Streptomyces tanashiensis.

Enzyme inhibitor

This glycosyl phosphoramidopeptide (FWfree-acid = 543.51 g/mol; CAS 36357-77-4), also systematically named as N-(a-rhamnopyranosyloxyhydroxyphosphinyl)- L-leucyl-L-tryptophan, is a slow-binding thermolysin inhibitor (Ki = 30 nM). Note: Phosphoramidon is an epimer of talopeptin. Stock 1 mg/mL aqueous solutions of phosphoramidon are stable for one month at –20°C. Target(s): atrolysin A; atrolysin C; bacillolysin; carboxypeptidase C, weakly inhibited; coccolysin; cytosol alanyl aminopeptidase, weakly inhibited; dactylysin; endothelin-converting enzyme; endothelin-converting enzyme 2; fungalysin; gametolysin; granzyme B; Legionella metalloendopeptidase; leucyl aminopeptidase, weakly inhibited; Listeria metalloprotease Mpl; lysine carboxypeptidase, or lysine(arginine) carboxypeptidase; carboxypeptidase N; mycolysin; neprilysin, or enkephalinase, Ki = 0.8 nM; oligopeptidase O; peptidyl-dipeptidase A, or angiotensin I-converting enzyme; pitrilysin, or protease Pi; pseudolysin, or Pseudomonas aeruginosa elastase; pyruvate decarboxylase; thermolysin (27,28,41,43- 53); urethanase; vibriolysin; and Xaa-Pro aminopeptidase, or aminopeptidase P.

PHOSPHORAMIDON Preparation Products And Raw materials

Raw materials

Preparation Products

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PHOSPHORAMIDON Suppliers

China 12 Germany 1 Japan 2 Switzerland 2 United Kingdom 4 United States 14 Global 35
MOLEKULA Ltd.
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36357-77-4, PHOSPHORAMIDONRelated Search:

PHOSPHORAMIDON--N/H PHOSPHORAMIDON SODIUM SALT, FROM MICROBIAL SOURCE,PHOSPHORAMIDON PHOSPHORAMIDON NA 2H20 GLYCYL-L-TRYPTOPHAN L-ALANYL-L-TRYPTOPHAN PHOSPHORAMIDON H-LEU-TRP-OH

  • N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT DIHYDRATE
  • N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN (SODIUM SALT)
  • N-(ALPHA-RHAMNOPYRANOSYLPHOSPHONO)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT
  • N-[N-[[(6-deoxy-alpha-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl]-L-tryptophan
  • N-[N-[(6-Deoxy-α-L-mannopyranosyloxy)hydroxyphosphinyl]-L-Leu-]-L-Trp-OH
  • L-Tryptophan,N-[[(6-deoxy-a-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl-
  • eucyl)-
  • l-tryptophan,n-(n-(((6-deoxy-alpha-l-mannopyranosyl)oxy)hydroxyphosphinyl)-l-l
  • n-(n-(((6-deoxy-alpha-l-mannopyranosyl)oxy)hydroxyphosphinyl)-l-leucyl)-l-tr
  • yptophan
  • PHOSPHORAMIDON
  • PHOSPHORAMIDON DISODIUM SALT DIHYDRATE
  • PHOSPHORAMIDON SODIUM SALT
  • N-(A-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP
  • N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP 2NA
  • N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP-OH
  • N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-LEU-TRP SODIUM SALT
  • N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN
  • N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, 2NA
  • N-(ALPHA-RHAMNOPYRANOSYLOXYHYDROXY-PHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN DISODIUM SALT
  • L-Tryptophan, N-[[(6-deoxy-α-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl-
  • 36357-77-4
  • BioChemical
  • Biochemicals and Reagents
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Type
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • P to Q
  • Phosphodiesterase 3',5'-Cyclic Nucleotide
  • Substrate Analogs
  • peptides
  • Pepetides