N-ACETYLTRYPTAMINE

Product Name: N-ACETYLTRYPTAMINE
CAS No.: 1016-47-3
Chemical Name: N-ACETYLTRYPTAMINE
Synonyms: Acetotryptamide;N-ACETYLTRYPTAMINE;Nb-Acetyltryptamine;N-(2-(1H-Indol-3-yl);N10-Acetyltryptamine;Acetyltryptamine, N-;TRYPTAMINE, N-ACETYL-;N-Acetyltryptamine >N-Acetyltryptamine;3-(2-Acetamidoethyl)indole
CBNumber: CB0329617
Molecular Formula: C12H14N2O
Formula Weight: 202.25
MOL File: 1016-47-3.mol

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N-ACETYLTRYPTAMINE Property

Melting point:: 74.0 to 78.0 °C
Boiling point:: 200°C/0.2mmHg(lit.)
Density: 1.164±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: alcohol: soluble
form: powder
pka: 16.48±0.46(Predicted)
color: White to Light yellow to Light orange
λmax: 290nm(MeOH)(lit.)
CAS DataBase Reference: 1016-47-3

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
HS Code: 2933.99.8290

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S307483
Product name: N-(2-(1H-INDOL-3-YL)-ETHYL)-ACETAMIDE
Purity: Aldrich
Packaging: 25mg
Price: $172
Updated: 2023/01/07

TCI Chemical

Product number: A2685
Product name: N-Acetyltryptamine
Purity: >98.0%(HPLC)
Packaging: 25mg
Price: $164
Updated: 2024/03/01

TCI Chemical

Product number: A2685
Product name: N-Acetyltryptamine
Purity: >98.0%(HPLC)
Packaging: 100mg
Price: $546
Updated: 2023/01/07

Cayman Chemical

Product number: 18605
Product name: N-acetyl Tryptamine
Purity: ≥98%
Packaging: 5mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 18605
Product name: N-acetyl Tryptamine
Purity: ≥98%
Packaging: 10mg
Price: $87
Updated: 2024/03/01

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N-ACETYLTRYPTAMINE Chemical Properties,Usage,Production

Description

The Argentinian medicinal plant Prosopsis nigra contains this alkaloid of the simple indole type which has recently been isolated and characterized. It may be a direct precursor in the biosynthesis of the {:l-carboline bases.

Description

N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT₂ receptor (K_i = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.

Uses

N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.

Definition

ChEBI: A tryptamine compound having an acetyl substituent attached to the side-chain amino function.

Enzyme inhibitor

This partial receptor agonist (FW = 202.26 g/mol; CAS 1016-47-3; Soluble to 100 mM in DMSO) is a melatonin (or 5-methoxy-N-acetyltryptamine) mimic and is more potent than melatonin in inhibiting dopamine release fom presynaptic melatonin receptor site of rabbit retina labeled in vitro with [3H]dopamine.

storage

Room temperature

References

Moro, Graziano, Coussio, Phytochern., 14,827 (1975)

N-ACETYLTRYPTAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-ACETYLTRYPTAMINE Suppliers

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1016-47-3, N-ACETYLTRYPTAMINERelated Search:

AC-TRP-OET AC-TRP-NH2 Melatonine 5-Hydroxy-N-acetyltryptamine N-Acetyl-DL-tryptophan BZ-TRP-OH 5-METHOXYCARBONYLAMINO-N-ACETYLTRYPTAMINE Tryptamine Z-HIS-PHE-TRP-OET AC-TRP-ONP 3-(2-FURYL)ACRYLOYL-L-TRYPTOPHAN METHYL ESTER Z-ALA-TRP-OH GLYCYL-DL-TRYPTOPHAN AC-TRP-OME H-LEU-TRP-LEU-OH 4-CHLOROBENZOYL-L-TRYPTOPHAN CALCIUM SALT Z-TRP-TRP-OH H-GLY-TRP-GLY-OH

Acetotryptamide

N-[2-(1H-Indol-3-yl)-ethyl]-acetamide

3-(2-N-ACETYLAMINOETHYL)INDOLE

3-[2-(Acetylamino)ethyl]-1H-indole

N-Acetyl-1H-indole-3-ethaneamine

N-[2-(1H-indol-3-yl)ethyl]ethanamide

N-(2-(1H-Indol-3-yl)

<i>N</i>-Acetyltryptamine

N-ACETYLTRYPTAMINE

TRYPTAMINE, N-ACETYL-

Acetamide,N-(2-indol-3-ylethyl)-

Acetamide,N-[2-(1H-indol-3-yl)ethyl]-

N-Acetyltryptamine &gt

3-(2-Acetamidoethyl)indole

N10-Acetyltryptamine,N ACETYLTRYPTAMINE,inhibit,N-Acetyltryptamine,Nω-Acetyltryptamine,Nb-Acetyltryptamine,Inhibitor,NACETYLTRYPTAMINE,Melatonin Receptor

N10-Acetyltryptamine

Nb-Acetyltryptamine

Acetyltryptamine, N-

1016-47-3