Tr-PEG3
- Product Name
- Tr-PEG3
- CAS No.
- 105589-77-3
- Chemical Name
- Tr-PEG3
- Synonyms
- Tr-PEG3;Tr-PEG2-OH;2-(2-(trityloxy)ethoxy)ethanol;Ethanol, 2-[2-(triphenylmethoxy)ethoxy]-;2-(2-(trityloxy)ethoxy)ethanol(WXPC0042)
- CBNumber
- CB03303331
- Molecular Formula
- C23H24O3
- Formula Weight
- 348.43
- MOL File
- 105589-77-3.mol
Tr-PEG3 Property
- Boiling point:
- 481.9±40.0 °C(Predicted)
- Density
- 1.127±0.06 g/cm3(Predicted)
- pka
- 14.35±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23415
- Product name
- Tr-PEG3
- Purity
- 95%
- Packaging
- 2g
- Price
- $320
- Updated
- 2021/12/16
- Product number
- P1021-00-N
- Product name
- 2-(2-(trityloxy)ethoxy)ethan-1-ol
- Purity
- 95%
- Packaging
- 1g
- Price
- $188
- Updated
- 2021/12/16
Tr-PEG3 Chemical Properties,Usage,Production
Description
Tr-PEG3 is a trityl ether protected PEG chain. The trityl ether can be removed under mildly acidic conditions or via hydrogenolysis. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Biological Activity
Tr-PEG2-OH is a PROTAC linker belonging to the PEG class. Can be used to synthesize PROTAC molecules. It is also a non-cleavable ADC linker containing 2-unit PEG, which can be used to synthesize antibody drug conjugates (ADC).
in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Non-cleavable < span> | PEGs
|
Tr-PEG3 Preparation Products And Raw materials
Raw materials
Preparation Products
Tr-PEG3 Suppliers
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- Country
- United States
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View Lastest Price from Tr-PEG3 manufacturers
- Product
- Tr-PEG2-OH 105589-77-3
- Price
- US $0.00/g
- Min. Order
- 100g
- Purity
- >98.00%
- Supply Ability
- 100g
- Release date
- 2024-03-27
- Product
- Tr-PEG3 105589-77-3
- Price
- US $2.00/g
- Min. Order
- 1g
- Purity
- 95~99.9%
- Supply Ability
- 5KG
- Release date
- 2020-03-05