Tr-PEG9
- Product Name
- Tr-PEG9
- CAS No.
- 1144113-16-5
- Chemical Name
- Tr-PEG9
- Synonyms
- Tr-PEG9;Tr-PEG8-OH;Trt-PEG8-OH;5-(trityloxy)-3,6,9,12,15,18,21-heptaoxatricosan-1-ol;2,5,8,11,14,17,20,23-Octaoxapentacosan-25-ol, 1,1,1-triphenyl-;2-(2-{2-[2-(2-{2-[2-(2-trityloxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy)ethanol
- CBNumber
- CB83163175
- Molecular Formula
- C35H48O9
- Formula Weight
- 612.75
- MOL File
- 1144113-16-5.mol
N-Bromosuccinimide Price
- Product number
- BP-23135
- Product name
- Tr-PEG9
- Purity
- 98%
- Packaging
- 250mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-23135
- Product name
- Tr-PEG9
- Purity
- 98%
- Packaging
- 5G
- Price
- $1900
- Updated
- 2021/12/16
- Product number
- P1062-00-N
- Product name
- 1,1,1-triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-ol
- Purity
- 95%
- Packaging
- 100mg
- Price
- $178
- Updated
- 2021/12/16
- Product number
- P1062-00-N
- Product name
- 1,1,1-triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-ol
- Purity
- 95%
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
Tr-PEG9 Chemical Properties,Usage,Production
Description
Tr-PEG9 is a PEG linker with a trityl protecting group and a terminal hydroxyl group. The trityl protecting group is used for primary alcohols and can be deprotected under mild acidic conditions. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media.
Uses
Tr-PEG8-OH is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
IC 50
Non-cleavable Linker; PEGs
References
[1] Adam M. Wawro, et al. Multigram chromatography-free synthesis of octa(ethylene glycol) p-toluenesulfonate. ORGANIC CHEMISTRY. 2016 Jul.
[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
Tr-PEG9 Preparation Products And Raw materials
Raw materials
Preparation Products
Tr-PEG9 Suppliers
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View Lastest Price from Tr-PEG9 manufacturers
- Product
- 5-(trityloxy)-3,6,9,12,15,18,21-heptaoxatricosan-1-ol 1144113-16-5
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- Tr-PEG8-OH 1144113-16-5
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-27