Tr-PEG6
- Product Name
- Tr-PEG6
- CAS No.
- 141282-24-8
- Chemical Name
- Tr-PEG6
- Synonyms
- Tr-PEG6;Tr-PEG5-OH;Trt-PEG5-OH;3,6,9,12,15-Pentaoxahexadecan-1-ol, 16,16,16-triphenyl-;2-[2-[2-[2-(2-trityloxyethoxy)ethoxy]ethoxy]ethoxy]ethanol
- CBNumber
- CB33303332
- Molecular Formula
- C29H36O6
- Formula Weight
- 480.59
- MOL File
- 141282-24-8.mol
Tr-PEG6 Property
- Boiling point:
- 595.6±45.0 °C(Predicted)
- Density
- 1.125±0.06 g/cm3(Predicted)
- pka
- 14.36±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- BP-23416
- Product name
- Tr-PEG6
- Purity
- 95%
- Packaging
- 1g
- Price
- $220
- Updated
- 2021/12/16
- Product number
- BP-23416
- Product name
- Tr-PEG6
- Purity
- 95%
- Packaging
- 2g
- Price
- $330
- Updated
- 2021/12/16
- Product number
- BP-23416
- Product name
- Tr-PEG6
- Purity
- 95%
- Packaging
- 5G
- Price
- $590
- Updated
- 2021/12/16
- Product number
- 185764
- Product name
- 2-(2-{2-[2-(2-Trityloxyethoxy)-ethoxy]-ethoxy}-ethoxy)ethanol
- Purity
- 95%
- Packaging
- 5g
- Price
- $826
- Updated
- 2021/12/16
- Product number
- 6574621
- Product name
- 2-(2-{2-[2-(2-Trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)ethanol
- Purity
- 95%
- Packaging
- 5G
- Price
- $500
- Updated
- 2021/12/16
Tr-PEG6 Chemical Properties,Usage,Production
Description
Tr-PEG6 is a trityl ether protected PEG chain. The trityl ether can be removed under mildly acidic conditions or via hydrogenolysis. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
Tr-PEG5-OH is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
IC 50
Non-cleavable Linker; PEGs
References
[1] Branderhorst HM, et al. Strong inhibition of cholera toxin binding by galactose dendrimers. Chem Commun (Camb). 2007 Dec 21;(47):5043-5. DOI:10.1039/b711070g
[2] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
Tr-PEG6 Preparation Products And Raw materials
Raw materials
Preparation Products
Tr-PEG6 Suppliers
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- 025-58367986 17351780683
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- China
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- 0086-371-86658258
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View Lastest Price from Tr-PEG6 manufacturers
- Product
- Tr-PEG5-OH 141282-24-8
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-27
- Product
- Tr-PEG6 141282-24-8
- Price
- US $2.00/g
- Min. Order
- 1g
- Purity
- 95~99.9%
- Supply Ability
- 5KG
- Release date
- 2020-03-05