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Methyl 5-formyl-2-hydroxybenzoate

Product Name
Methyl 5-formyl-2-hydroxybenzoate
CAS No.
41489-76-3
Chemical Name
Methyl 5-formyl-2-hydroxybenzoate
Synonyms
-2-hydroxybenzoate;Methyl 5-Formylsalicylate;Methyl5-Formylsalicylate>Methyl 5-formyl-2-hydroxybenzoate;5-formylsalicylic acid methyl ester;2-Hydroxy-5-formylbenzoic acid methyl ester;5-FORMYL-2-HYDROXYBENZOIC ACID METHYL ESTER;Benzoic acid, 5-formyl-2-hydroxy-, methyl ester;Isophthalaldehydic acid, 6-hydroxy-, methyl ester;Methyl 5-formyl-2-hydroxybenzoate in stock Factory
CBNumber
CB0333724
Molecular Formula
C9H8O4
Formula Weight
180.16
MOL File
41489-76-3.mol
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Methyl 5-formyl-2-hydroxybenzoate Property

Melting point:
79.0 to 83.0 °C
Boiling point:
294.5±25.0 °C(Predicted)
Density 
1.310±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to crystal
pka
7.57±0.18(Predicted)
color 
White to Light yellow
InChI
InChI=1S/C9H8O4/c1-13-9(12)7-4-6(5-10)2-3-8(7)11/h2-5,11H,1H3
InChIKey
XJKWVPNWHOCFBR-UHFFFAOYSA-N
SMILES
C(OC)(=O)C1=CC(C=O)=CC=C1O
CAS DataBase Reference
41489-76-3
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2082
Product name
Methyl 5-Formylsalicylate
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$49
Updated
2025/07/31
TCI Chemical
Product number
M2082
Product name
Methyl 5-Formylsalicylate
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$138
Updated
2025/07/31
TRC
Product number
M305535
Product name
Methyl 5-Formylsalicylate
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
M305535
Product name
Methyl 5-Formylsalicylate
Packaging
500mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
J57460
Product name
Methyl5-formyl-2-hydroxybenzoate
Packaging
25g
Price
$114
Updated
2021/12/16
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Methyl 5-formyl-2-hydroxybenzoate Chemical Properties,Usage,Production

Synthesis

67-56-1

616-76-2

41489-76-3

5-Formyl-2-hydroxybenzoic acid (500 g, 30 mmol, Sigma-Aldrich) was used as a raw material, mixed with concentrated H2SO4 (200 mL) and methanol (50 mL), and the reaction was stirred under reflux conditions for 24 hours. After completion of the reaction, the mixture was concentrated under reduced pressure to give 536 g of methyl 5-formyl-2-hydroxybenzoate (compound of formula FO) as a colorless oil in 99% yield.

References

[1] Patent: WO2009/27820, 2009, A2. Location in patent: Page/Page column 232
[2] Patent: US2014/155391, 2014, A1. Location in patent: Paragraph 0632; 0633
[3] Journal of Organic Chemistry, 2017, vol. 82, # 16, p. 8580 - 8589
[4] Patent: EP2143710, 2010, A1. Location in patent: Page/Page column 29
[5] Patent: EP2332942, 2011, A1. Location in patent: Page/Page column 22

Methyl 5-formyl-2-hydroxybenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 5-formyl-2-hydroxybenzoate Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from Methyl 5-formyl-2-hydroxybenzoate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Methyl 5-formyl-2-hydroxybenzoate 41489-76-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2025-03-14
Chemwill Asia Co.,Ltd.
Product
Methyl 5-formyl-2-hydroxybenzoate in stock Factory 41489-76-3
Price
US $1.00/KG
Min. Order
1KG
Purity
TOP 3 Factory in China
Supply Ability
Top 3 largest production capacity Factory
Release date
2019-04-03
Career Henan Chemical Co
Product
Methyl 5-formyl-2-hydroxybenzoate 41489-76-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-12-24

41489-76-3, Methyl 5-formyl-2-hydroxybenzoateRelated Search:


  • 5-FORMYL-2-HYDROXYBENZOIC ACID METHYL ESTER
  • Methyl 5-formyl-2-hydroxybenzoate
  • 5-formylsalicylic acid methyl ester
  • 2-Hydroxy-5-formylbenzoic acid methyl ester
  • Methyl 5-Formylsalicylate
  • 5-Formylsalicylic Acid Methyl Ester Methyl 5-Formyl-2-hydroxybenzoate 5-Formyl-2-hydroxybenzoic Acid Methyl Ester
  • Isophthalaldehydic acid, 6-hydroxy-, methyl ester
  • Methyl 5-formyl-2-hydroxybenzoate in stock Factory
  • Methyl5-Formylsalicylate&gt
  • Benzoic acid, 5-formyl-2-hydroxy-, methyl ester
  • -2-hydroxybenzoate
  • 41489-76-3
  • API intermediates
  • Acids and Derivatives
  • Carbonyl Compounds