ChemicalBook > CAS DataBase List > Mal-amido-PEG7-acid

Mal-amido-PEG7-acid

Product Name
Mal-amido-PEG7-acid
CAS No.
2112731-42-5
Chemical Name
Mal-amido-PEG7-acid
Synonyms
Mal-NH-PEG7-acid;Mal-NH-PEG7-COOH;Mal-amido-PEG7-COOH;Mal-amido-PEG7-acid;Mal-amido-PEG7-propionic acid;Mal-CH2CH2CONH-PEG7-CH2CH2COOH;Mal-amido-PEG7-acid?Chemical Structure;MalamidoPEG7acid,PROTAC Linkers,Mal amido PEG7 acid,inhibit,Inhibitor;1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25-heptaoxa-4-azaoctacosan-28-oic acid;4,7,10,13,16,19,22-Heptaoxa-25-azaoctacosanoic acid, 28-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-26-oxo-
CBNumber
CB03373640
Molecular Formula
C24H40N2O12
Formula Weight
548.58
MOL File
2112731-42-5.mol
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Mal-amido-PEG7-acid Property

InChIKey
LHEVLPWUXYBIOW-UHFFFAOYSA-N
SMILES
C(O)(=O)CCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

purepeg
Product number
436207
Product name
Maleimide-NH-PEG7-CH2CH2COOH
Purity
min.97%
Packaging
250mg
Price
$145
Updated
2021/12/16
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Mal-amido-PEG7-acid Chemical Properties,Usage,Production

Uses

Mal-amido-peg7-acid is a useful research chemical, a PEG linker and a PEG reagent.

Biological Activity

Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Mal-amido-PEG7-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-amido-PEG7-acid Suppliers

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View Lastest Price from Mal-amido-PEG7-acid manufacturers

LAURENT
Product
Mal-NH-PEG7-CH2CH2COOH 2112731-42-5
Price
US $950.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-24
Xian confluore Biological Technology Co., Ltd.
Product
Mal-amido-PEG7-acid 2112731-42-5
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-27

2112731-42-5, Mal-amido-PEG7-acidRelated Search:


  • Mal-amido-PEG7-acid
  • Mal-NH-PEG7-acid
  • Mal-amido-PEG7-COOH
  • Mal-NH-PEG7-COOH
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  • Mal-amido-PEG7-propionic acid
  • 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25-heptaoxa-4-azaoctacosan-28-oic acid
  • MalamidoPEG7acid,PROTAC Linkers,Mal amido PEG7 acid,inhibit,Inhibitor
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  • Mal-CH2CH2CONH-PEG7-CH2CH2COOH
  • Mal-amido-PEG7-acid?Chemical Structure
  • 2112731-42-5
  • C24H40N2O12
  • peg