Propargyl-PEG5-CH2CO2-NHS
- Product Name
- Propargyl-PEG5-CH2CO2-NHS
- CAS No.
- 1161883-51-7
- Chemical Name
- Propargyl-PEG5-CH2CO2-NHS
- Synonyms
- Propargyl-PEG4-CH2COONHS;Propargyl-PEG5-CH2CO2-NHS;Propargyl-PEG4-O-C1-NHS ester;Propargyl-PEG4-CH2CONHS ester;Propargyl-PEG5-CH2COO-NHS ester;Propargyl-PEG5-CH2COOH NHS Ester;2,5-dioxopyrrolidin-1-yl 3,6,9,12,15-pentaoxaoctadec-17-ynoate;3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB03373761
- Molecular Formula
- C17H25NO9
- Formula Weight
- 387.38
- MOL File
- 1161883-51-7.mol
Propargyl-PEG5-CH2CO2-NHS Property
- storage temp.
- Storage temp. -20°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Viscous Liquid
- color
- Colorless to light brown
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-23812
- Product name
- Propargyl-PEG5-CH2CO2-NHS
- Packaging
- 100mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-23812
- Product name
- Propargyl-PEG5-CH2CO2-NHS
- Packaging
- 500mg
- Price
- $680
- Updated
- 2021/12/16
- Product number
- BP-23812
- Product name
- Propargyl-PEG5-CH2CO2-NHS
- Packaging
- 1g
- Price
- $980
- Updated
- 2021/12/16
Propargyl-PEG5-CH2CO2-NHS Chemical Properties,Usage,Production
Description
Propargyl-PEG5-CH2CO2-NHS is an amine reactive linker with an alkyne moeity which can react with azide-bearing biomolecules in copper catalyzed Click Chemistry reactions. The PEG units enhance the solubility of the linker in aqueous media.
Uses
Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs; Alkyl/ether
References
[1] Kussrow A, et al. Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scatteringinterferometry. Anal Chem. 2009 Jun 15;81(12):4889-97. DOI:10.1021/ac900569c
Propargyl-PEG5-CH2CO2-NHS Preparation Products And Raw materials
Raw materials
Preparation Products
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