MOZ-IN-3

ChemicalBook > CAS DataBase List > MOZ-IN-3

Product Name: MOZ-IN-3
CAS No.: 2055397-18-5
Chemical Name: MOZ-IN-3
Synonyms: MOZ-IN-3;KAT6B inhibitor;KAT6A inhibitor;MOZ-IN-3/WM-8014;WM-8014;WM 8014;WM8014;KAT6A INHIBITOR; KAT6B INHIBITOR;N’-(4-Fluoro-5-methylbiphenyl-3-carbonyl)benzenesulfonohydrazide;N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)benzenesulfonohydrazide;WM-8014,HAT,inhibit,Inhibitor,HATs,WM 8014,Histone Acetyltransferase,WM8014;1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-5-methyl-, 3-(phenylsulfonyl)hydrazide;[1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-5-methyl-, 2-(phenylsulfonyl)hydrazide
CBNumber: CB03376843
Molecular Formula: C20H17FN2O3S
Formula Weight: 384.42
MOL File: 2055397-18-5.mol

Less

MOZ-IN-3 Property

Density: 1.307±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 50 mg/ml; DMF:PBS (pH 7.2) (1:7): 0.1 mg/ml; DMSO: 33 mg/ml; Ethanol: 2 mg/ml
form: A crystalline solid
pka: 7.15±0.25(Predicted)

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 27402
Product name: MOZ-IN-3
Packaging: 1mg
Price: $65
Updated: 2024/03/01

Cayman Chemical

Product number: 27402
Product name: MOZ-IN-3
Packaging: 5mg
Price: $178
Updated: 2024/03/01

Cayman Chemical

Product number: 27402
Product name: MOZ-IN-3
Packaging: 500μg
Price: $37
Updated: 2024/03/01

TRC

Product number: M732725
Product name: MOZ-IN-3
Packaging: 25mg
Price: $1100
Updated: 2021/12/16

ChemScene

Product number: CS-0022886
Product name: WM-8014
Purity: 99.64%
Packaging: 25mg
Price: $1100
Updated: 2021/12/16

Less

MOZ-IN-3 Chemical Properties,Usage,Production

Description

MOZ-IN-3 is an inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ) and KAT6B/MORF (IC₅₀s = 8 and 28 nM, respectively). It is selective for KAT6A and KAT6B over KAT5 and KAT7 (IC₅₀s = 224 and 342 nM, respectively). MOZ-IN-3 induces cell cycle arrest in and inhibits proliferation of mouse embryonic fibroblasts (IC₅₀ = 2.4 μM) and inhibits proliferation of EMRK1184 lymphoma cells (IC₅₀ = 2.3 μM). It induces genetic and morphological changes associated with cellular senescence without inducing DNA damage, apoptosis, or necrosis. MOZ-IN-3 (10 μM) decreases global levels of acetylated histone H3 lysine 14 (H3K14Ac) by 49% and reduces H3K9Ac levels at the transcription start sites of Ezh2, Melk, and E2f2.

Uses

MOZ-IN-3 is a highly potent and selective inhibitor of lysine acetyltransferases, KAT6A and KAT6B.

storage

Store at -20°C

MOZ-IN-3 Preparation Products And Raw materials

Raw materials

Preparation Products

Less

MOZ-IN-3 Suppliers

China 48 United States 4 Global 52

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4153
Advantage: 55

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 3501
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2990
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9756
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
Advantage: 58

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

Beyond Pharmaceutical Co., Ltd

Tel: +86-0571-81953185; 15381198709 +86-15381198709
Fax: 0571-89086206
Email: jasonyao@beyond-pharma.com
Country: China
ProdList: 830
Advantage: 60

Twochem Co.Ltd.

Tel: 021-58111628 15800915896
Fax: QQ 3285589261
Country: China
ProdList: 1988
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3242
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 9944
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9730
Advantage: 58

Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

Tel: 18081075745
Email: chemflowtech@sina.com
Country: China
ProdList: 1886
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9414
Advantage: 58

Changzhou Chenhong Biotechnology Co., Ltd.

Tel: 0519-85788828 13775037613
Email: sales@chemrenpharm.com
Country: China
ProdList: 3553
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-020-82000279 18988968278
Fax: QQ：3283937693
Email: sales@ubiochem.com
Country: China
ProdList: 2414
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 15000105423
Email: chenjw@absin.cn
Country: China
ProdList: 24734
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

Tel: +86-021-61551413 +8618813727289
Email: contact@trustwe.com
Country: China
ProdList: 5738
Advantage: 58

Shanghai Luofa Biochemical Technology Co., Ltd.

Tel: 021-51111890 15317326293
Email: sales@molnova.com
Country: China
ProdList: 4196
Advantage: 58

Advanced chemblocks inc

Tel: 650-6922368
Email: sales@achemblock.com
Country: China
ProdList: 2992
Advantage: 58

Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15342225168
Email: yutianchun2007@126.com
Country: China
ProdList: 10007
Advantage: 58

cjbscvictory

Tel: 13348960310 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 9946
Advantage: 58

Abmole Bioscience Inc.

Tel: 021-50967598 02150967598
Email: sales@abmole.cn
Country: China
ProdList: 4495
Advantage: 58

Hebei Weite Medical Technology Co., Ltd

Tel: 13180081292
Email: contact@wetogethermed.com
Country: China
ProdList: 7305
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 8000
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 18768175414
Email: gaojun@univ-bio.com
Country: China
ProdList: 24998
Advantage: 58

Hubei Kele Fine Chemical Co., Ltd

Tel: 027-59101668 19945030958
Fax: 027-59101668
Email: 2881924765@qq.com
Country: China
ProdList: 7977
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Email: product02@bidepharm.com
Country: China
ProdList: 61720
Advantage: 58

Kaifeng Mingren Pharmaceutical Co.,LTD

Tel: 0371-65741762
Fax: QQ：2860768577
Email: sales@hasunny.com
Country: China
ProdList: 2380
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6712
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9892
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24023
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2853979810@qq.com
Country: China
ProdList: 9919
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 8740
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12007
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: +86-18521732826
Email: market@aladdin-e.com
Country: China
ProdList: 48467
Advantage: 58

Olix (Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 17316404525
Email: 209533805@qq.com
Country: China
ProdList: 9628
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 32686
Advantage: 60

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6846
Advantage: 58

Wuhan Boot Biotechnology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6829
Advantage: 58

Guangzhou Weijia Technology Co., Ltd.

Tel: --
Fax: --
Email: WHIGA22@126.COM
Country: CHINA
ProdList: 6748
Advantage: 58

Shanghai Minmin Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1914109725@qq.com
Country: CHINA
ProdList: 6530
Advantage: 58

Shenzhen Branch Science and Technology Co., Ltd.

Tel: --
Fax: --
Email: zikerbio@163.com
Country: CHINA
ProdList: 6478
Advantage: 58

Shanghai Jingke Chemical Technology Co., Ltd.

Tel: --
Fax: --
Email: jingkehuaxue@163.com
Country: CHINA
ProdList: 6974
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: --
Fax: --
Email: kexianxun@gmail.com
Country: China
ProdList: 1039
Advantage: 50

2055397-18-5, MOZ-IN-3Related Search:

WM-2474 WM-3835 D18 2-Fluoro-N-(3-fluoro-5-pyridin-2-yl-benzoyl)-benzenesulfonhydrazine

MOZ-IN-3

KAT6A inhibitor

KAT6B inhibitor

WM-8014;WM 8014;WM8014;KAT6A INHIBITOR; KAT6B INHIBITOR

MOZ-IN-3/WM-8014

[1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-5-methyl-, 2-(phenylsulfonyl)hydrazide

1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-5-methyl-, 3-(phenylsulfonyl)hydrazide

WM-8014,HAT,inhibit,Inhibitor,HATs,WM 8014,Histone Acetyltransferase,WM8014

N’-(4-Fluoro-5-methylbiphenyl-3-carbonyl)benzenesulfonohydrazide

N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)benzenesulfonohydrazide

2055397-18-5