FMOC-DAB-OH HCL
- Product Name
- FMOC-DAB-OH HCL
- CAS No.
- 161420-87-7
- Chemical Name
- FMOC-DAB-OH HCL
- Synonyms
- FMOC-DAB-OH;FMOC-DAB;FMOC-L-2,4-DIAMINOBUTYRIC ACID;Fmoc-L-Dab;FMOC-L-DAB-OH;FMOC-DAB-OH HCL;FMOC-DAB-OH . HCI;N-α-Fmoc-L-2,4-diaminobutyricacid;N-α-Fmoc-L-2,4-diaminobutyric acid;(S)-N2-Fmoc-2,4-diaminobutyric Acid
- CBNumber
- CB0338633
- Molecular Formula
- C19H20N2O4
- Formula Weight
- 340.37
- MOL File
- 161420-87-7.mol
FMOC-DAB-OH HCL Property
- Melting point:
- 169.5-171.7 °C
- Boiling point:
- 593.7±50.0 °C(Predicted)
- Density
- 1.294±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- form
- Powder
- pka
- 3.52±0.10(Predicted)
- color
- White to off-white
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F1225
- Product name
- (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-4-aminobutanoic Acid
- Packaging
- 1G
- Price
- $215
- Updated
- 2025/07/31
- Product number
- F620038
- Product name
- Fmoc-dab-oh
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 277267
- Product name
- N-alpha-Fmoc-L-2,4-diaminobutyric acid
- Packaging
- 500mg
- Price
- $333
- Updated
- 2021/12/16
- Product number
- AS29196
- Product name
- (S)-N2-Fmoc-2,4-diaminobutyric Acid
- Purity
- 98+% ee
- Packaging
- 1g
- Price
- $34
- Updated
- 2021/12/16
- Product number
- AS29196
- Product name
- (S)-N2-Fmoc-2,4-diaminobutyric Acid
- Purity
- 98+% ee
- Packaging
- 5G
- Price
- $101
- Updated
- 2021/12/16
FMOC-DAB-OH HCL Chemical Properties,Usage,Production
Synthesis
71989-20-3
161420-87-7
The general procedure for the synthesis of Fmoc-L-2,4-diaminobutyric acid (Fmoc-Dab-OH) from (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-amino-5-oxopentanoic acid (Fmoc-Gln-OH) was as follows: A. 100 g (271.5 mmol) of Fmoc-Gln-OH was suspended in 2 L of a solvent mixture consisting of ethyl acetate, acetonitrile and water in the ratio of 2:1:1 by volume. 105.1 g (325.9 mmol) of diisopropylethylamine (DIPA) was slowly added at 20-30 °C and the reaction lasted for 72 hours. Upon completion of the reaction, 80 g of Fmoc-Dab-OH was obtained after post-processing in 86.5% yield. The product was analyzed by high performance liquid chromatography (HPLC) showing a purity of 99.6%, and its structural correctness was confirmed by infrared spectroscopy (IR) and nuclear magnetic resonance (NMR), and the relevant spectra are shown in Figures 1 and 2.
References
[1] Bulletin of the Chemical Society of Japan, 2004, vol. 77, # 10, p. 1915 - 1924
[2] Patent: CN105348147, 2016, A. Location in patent: Paragraph 0014
[3] Synlett, 2011, # 13, p. 1917 - 1919
[4] Journal of Peptide Science, 2017, vol. 23, # 3, p. 202 - 214
[5] European Journal of Medicinal Chemistry, 1995, vol. 30, # 2, p. 115 - 122
FMOC-DAB-OH HCL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from FMOC-DAB-OH HCL manufacturers
- Product
- FMOC-DAB-OH HCL 161420-87-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 2000
- Release date
- 2025-04-21
- Product
- FMOC-DAB-OH HCL 161420-87-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,100kg
- Release date
- 2019-07-04