N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide

Product Name: N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide
CAS No.: 850935-88-5
Chemical Name: N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide
Synonyms: 1650-M15;WAY-326687;N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide;Benzamide, N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[(2-methyl-1-piperidinyl)sulfonyl]-
CBNumber: CB03509609
Molecular Formula: C18H22N4O4S
Formula Weight: 390.46
MOL File: 850935-88-5.mol

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N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide Property

Density: 1.390±0.06 g/cm3(Predicted)
pka: 10.02±0.70(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide Chemical Properties,Usage,Production

Uses

1650-M15 is an inhibitor of lipoteichoic acid synthase (LtaS). It has inhibitory activity against Gram-positive bacteria but has no significant inhibitory effect against Gram-negative bacteria. The IC50s of 1650-M15 against MRSA and MSSA are 62.44 μM and 66.42 μM, respectively, and the MICs are both 200 μM[1].

References

[1] Methods and compositions for inhibiting gram positive bacteria. United States, US20150246024 A1, 2015-09-03.

N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide Suppliers

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850935-88-5, N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamideRelated Search:

2H-Indol-2-one, 1,3-dihydro-3-[(5-methyl-2-furanyl)methylene]- N-[2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2-PYRIDINYL-CYCLOHEXANECARBOXAMIDE MALEATE 1-(1,3-benzodioxol-5-ylmethyl)-4-[(3,4-dimethoxyphenyl)sulfonyl]piperazine N-(4-chlorophenyl)-2-(thiophen-2-yl)acetamide (4-benzylpiperidin-1-yl)(4-fluorophenyl)methanone Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]- Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- 3-(3,5-dimethyl-1H-pyrazol-1-yl)-N-(4-methylphenyl)propanamide 5-(3-bromophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione N-(6-bromobenzo[d]thiazol-2-yl)cyclohexanecarboxamide 1-(4-fluorobenzoyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine Benzamide, N-methyl-4-phenoxy-N-(phenylmethyl)- Benzenesulfonamide, N,N'-1,2-ethanediylbis[3-methyl- Acetamide, N-1H-benzimidazol-2-yl-2-phenoxy- 3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione WAY-234759 2-(1,3-benzoxazol-2-ylsulfanyl)-N-phenylacetamide 2-benzylsulfanyl-5-(4-methylphenyl)-1,3,4-oxadiazole

N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide

Benzamide, N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[(2-methyl-1-piperidinyl)sulfonyl]-

WAY-326687

1650-M15

850935-88-5