CBZ-L-ALANINOL

Product Name: CBZ-L-ALANINOL
CAS No.: 66674-16-6
Chemical Name: CBZ-L-ALANINOL
Synonyms: Z-ALA-OL;Z-ALANINOL;Z-L-Ala-ol;Z-L-ALANINOL;Cbz-L-Ala-OL;CBZ-L-ALANINOL;N-Z-L-ALANINOL;Z-L-alaninol≥ 99% (HPLC);N-CARBOBENZOXY-L-ALANINOL;N-Carbobenzyloxy-L-alaninol
CBNumber: CB0351605
Molecular Formula: C11H15NO3
Formula Weight: 209.24
MOL File: 66674-16-6.mol

More

Less

CBZ-L-ALANINOL Property

Melting point:: 81-84 °C (lit.)
Boiling point:: 375.2±35.0 °C(Predicted)
Density: 1.149±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in ethanol.
form: powder to crystal
pka: 11.90±0.46(Predicted)
color: White to Almost white
optical activity: [α]20/D 8.0, c = 2% in ethanol
CAS DataBase Reference: 66674-16-6(CAS DataBase Reference)

More

Less

Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29221990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 543217
Product name: N-Z-L-Alaninol
Purity: 98%
Packaging: 5g
Price: $163
Updated: 2023/01/07

TCI Chemical

Product number: C2629
Product name: N-Carbobenzoxy-L-alaninol
Purity: >98.0%(HPLC)(N)
Packaging: 1g
Price: $23
Updated: 2025/07/31

TCI Chemical

Product number: C2629
Product name: N-Carbobenzoxy-L-alaninol
Purity: >98.0%(HPLC)(N)
Packaging: 5g
Price: $69
Updated: 2025/07/31

Usbiological

Product number: 260735
Product name: Z-L-alaninol
Packaging: 2g
Price: $333
Updated: 2021/12/16

TRC

Product number: B194030
Product name: (S)-Benzyl(1-Hydroxypropan-2-yl)carbamate
Packaging: 1g
Price: $75
Updated: 2021/12/16

More

Less

CBZ-L-ALANINOL Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

N-Benzyloxycarbonyl-L-alaninol is used as an important organic intermediate. It is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

1142-20-7

6429-44-3

GENERAL METHODS: To a solution of benzyloxycarbonyl-L-alanine (10 mmol) in tetrahydrofuran (THF, 10 mL) was added N,N-diisopropylethylamine (DIPEA, 11 mmol, 1.42 mL) and a solution of 50% propylphosphonic anhydride (T3P) in ethyl acetate (EtOAc) (20 mmol, 6.36 mL) at 0°C with stirring for about 10 minutes. Then sodium borohydride (NaBH4) aqueous solution (10 mmol, 388 mg, dissolved in 0.3 mL of water) was slowly added to the reaction mixture at the same temperature, and the progress of the reaction was monitored by thin-layer chromatography (TLC) until the reaction was completed. Upon completion of the reaction, the solvent was removed by evaporation under reduced pressure, and the crude product was dissolved in ethyl acetate (EtOAc), and the organic phase was washed sequentially with 5% aqueous citric acid (10 mL x 2), 5% aqueous sodium carbonate (Na2CO3) (10 mL x 2), water and saturated saline. The organic phase was dried over anhydrous sodium sulfate (Na2SO4) and the solvent was evaporated under reduced pressure to obtain the target compound.

References

[1] Antimicrobial Agents and Chemotherapy, 2017, vol. 61, # 3,
[2] Tetrahedron Letters, 2012, vol. 53, # 38, p. 5059 - 5063
[3] Tetrahedron Letters, 1992, vol. 33, # 30, p. 4257 - 4260
[4] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 7, p. 1975 - 1980
[5] Tetrahedron: Asymmetry, 1992, vol. 3, # 11, p. 1401 - 1410

CBZ-L-ALANINOL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CBZ-L-ALANINOL Suppliers

Americas 1 Canada 1 China 119 Europe 2 Germany 3 India 7 Japan 4 Switzerland 3 United Kingdom 3 United States 28 Global 171

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Atop-Pharma (Shanghai) Technology Co., Ltd.

Tel: +86 (21) 5196-9732
Fax: +86 (21) 5196-9733
Country: China
ProdList: 996
Advantage: 57

More

Less

View Lastest Price from CBZ-L-ALANINOL manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Cbz-L-Ala-OL 66674-16-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-12-18

Henan Aochuang Chemical Co.,Ltd.

Product: CBZ-L-ALANINOL 66674-16-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Zhuozhou Wenxi import and Export Co., Ltd

Product: CBZ-L-ALANINOL 66674-16-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

66674-16-6, CBZ-L-ALANINOLRelated Search:

N-Cbz-L-Serine L-Alaninol Cbz-Gly-Gly Z-GLY-NH2 N-Benzyloxycarbonyl-6-aminohexanoic acid N-Benzyloxycarbonyl-D-aspartic acid Z-AIB-OH N-Carbobenzyloxy-L-glutamine N-Benzyloxycarbonyl-L-asparagine N-Carbobenzyloxy-L-valine Z-CYS(BZL)-OH N-Cbz-L-glutamic acid Nalpha-Cbz-L-Arginine N-Carbobenzyloxy-L-alanine N-Carbobenzyloxy-L-aspartic acid N-Cbz-L-Phenylalanine N,N'-Bis(benzyloxycarbonyl)-L-cystine CBZ-D-ALANINOL,N-CBZ-D-ALANINOL

(S)-(2-HYDROXY-1-METHYLETHYL)CARBAMIC ACID BENZYL ESTER

(S)-(-)-2-(Z-AMINO)-1-PROPANOL

N-CARBOBENZOXY-L-ALANINOL

N-Z-L-ALANINOL

Z-ALA-OL

Z-ALANINOL

Z-L-ALANINOL

CBZ-L-ALANINOL

(-)-N-[(S)-2-Hydroxy-1-methylethyl]carbamic acid benzyl ester

(S)-2-(Benzyloxycarbonylamino)-1-propanol

N-[(S)-1-(Hydroxymethyl)ethyl]carbamic acid benzyl ester

N-[(S)-2-Hydroxy-1-methylethyl]carbamic acid benzyl ester

N-Benzyloxycarbonyl-L-alaninol

(S)-benzyl 1-hydroxypropan-2-ylcarbamate

N-Cbz-L-alaninol (S)-N-Cbz-2-Amino-1-propanol

Cbz-L-Ala-OL

N-Carbobenzoxy-L-alaninol

Z-L-alaninol≥ 99% (HPLC)

Z-L-Ala-ol

N-[(S)-2-Hydroxy-1-methylethyl]carbamic Acid Phenylmethyl Ester

N-Carbobenzoxy-L-alaninol &gt

Carbamic acid, N-[(1S)-2-hydroxy-1-methylethyl]-, phenylmethyl ester

(S)-N-Benzyloxycarbonyl-2-Amino-1-propanol

(S)-N-Cbz-2-Amino-1-propanol

N-Carbobenzyloxy-L-alaninol

benzyl N-[(1S)-2-hydroxy-1-methyl-ethyl]carbamate

Benzyl [(2S)-1-hydroxy-2-propanyl]carbamate

N-Z-<sc>L</sc>-Alaninol

66674-16-6

C6H5CH2O2CNHCHCH3CH2OH

C6H5CH2O2CNHCHCH3CH2

Peptide Synthesis

Specialty Synthesis

Amino Alcohols

Amino Acid Derivatives