3-Aminobenzeneboronic acid hemisulfate salt
- Product Name
- 3-Aminobenzeneboronic acid hemisulfate salt
- CAS No.
- 66472-86-4
- Chemical Name
- 3-Aminobenzeneboronic acid hemisulfate salt
- Synonyms
- 3-AMINOPHENYLBORONIC ACID HEMISULFATE;M-APBA;SKL266;3-Aminobenzeneboroni;boronic acid hemisuL;M-AMINOPHENYLBORIC ACID HEMISULFATE;(3-aminophenyl)-boronic aci sulfate;aminophenylboronic acid hemisulfate;3-aminophenylboric acid hemisulphate;M-AMINOPHENYLBORONIC ACID HEMISULFATE
- CBNumber
- CB0357728
- Molecular Formula
- C12H18B2N2O8S
- Formula Weight
- 371.96692
- MOL File
- 66472-86-4.mol
3-Aminobenzeneboronic acid hemisulfate salt Property
- Melting point:
- ≥300 °C
- storage temp.
- Inert atmosphere,2-8°C
- Water Solubility
- Soluble in water
- form
- Crystalline Powder
- color
- White to slightly beige
- Sensitive
- Hygroscopic
- BRN
- 8094151
- InChIKey
- XMVGYYBQCXVVHU-UHFFFAOYSA-N
- CAS DataBase Reference
- 66472-86-4
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- F
- 3-10
- HazardClass
- IRRITANT
- HS Code
- 29310095
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- A71751
- Product name
- 3-Aminophenylboronic acid hemisulfate salt
- Purity
- ≥95%
- Packaging
- 5g
- Price
- $136
- Updated
- 2024/03/01
- Product number
- A71751
- Product name
- 3-Aminophenylboronic acid hemisulfate salt
- Purity
- ≥95%
- Packaging
- 25g
- Price
- $440
- Updated
- 2024/03/01
- Product number
- A1774
- Product name
- 3-Aminophenylboronic Acid Hemisulfate
- Packaging
- 1g
- Price
- $31
- Updated
- 2024/03/01
- Product number
- A1774
- Product name
- 3-Aminophenylboronic Acid Hemisulfate
- Packaging
- 5g
- Price
- $94
- Updated
- 2024/03/01
- Product number
- A17240
- Product name
- 3-Aminobenzeneboronic acid hemisulfate, 98+%
- Packaging
- 1g
- Price
- $33.65
- Updated
- 2024/03/01
3-Aminobenzeneboronic acid hemisulfate salt Chemical Properties,Usage,Production
Chemical Properties
White to slightly beige crystalline powder
Uses
3-Aminobenzeneboronic acid hemisulfate salt is a boronic acid derivative, which can be used as an intermediate in pharmaceutical synthesis. Adsorbent additive for the chromatographic separation of 3'-terminal polynucleotides from RNA.
Application
3-Aminophenylboronic acid hemisulfate salt is used in the synthesis of:
Phenylboronic acid-functionalized inverse opal hydrogels within microfluidic flow cells for glucose sensing.
Phenylboronic acid-salicylhydroxamic acid-derived complexing reagent for protein immobilization on chromatographic support.
It can also be used in the preparation of phenylboronic acid (PBA) monolayer-modified Au electrode for the voltammetric sensing of uridine and cytidine.
Preparation
3-Aminobenzeneboronic acid hemisulfate salt synthesis: Benzenamine, 3-bromo-N-(diphenylmethylene)- (80,0 g; 0.24 moles) was added to the cryogenic reactor along with 1.4 equivalents of triisopropyl borate and dissolved in tetrahydrofuran. The resulting solution was cooled to -80°C under an inert atmosphere and 1.35 equivalents of n-butyllithium (as a solution in n-hexane) was added maintaining the internal temperature. When complete conversion was achieved, the reaction mixture was added to a dilute mixture of sulfuric acid (1 M) and toluene. The layers were separated to obtain an aqueous solution of 3-aminophenylboronic acid hydrogen sulfate (assay yield: 85%). 3-Aminobenzeneboronic acid hemisulfate salt can be obtained by precipitating a 0.5 M aqueous solution at pH 7.2 (pH corrected with 33% aqueous NaOH) at a temperature of 0-5°C. Filtration and drying under vacuum at 40°C for 8 hours yielded 21.7 g of 3-Aminobenzeneboronic acid hemisulfate salt (0.16 moles; 66% molar yield).
3-Aminobenzeneboronic acid hemisulfate salt Preparation Products And Raw materials
Raw materials
Preparation Products
3-Aminobenzeneboronic acid hemisulfate salt Suppliers
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View Lastest Price from 3-Aminobenzeneboronic acid hemisulfate salt manufacturers
- Product
- 3-Aminobenzeneboronic acid hemisulfate salt 66472-86-4
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2020-04-26
- Product
- 3-Aminophenylboronic Acid Hemisulfate 66472-86-4
- Price
- US $10.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 20 Tons
- Release date
- 2021-11-25
- Product
- 3-Aminobenzeneboronic acid hemisulfate salt 66472-86-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2019-08-07