ChemicalBook > CAS DataBase List > N-Formylglycine

N-Formylglycine

Product Name
N-Formylglycine
CAS No.
2491-15-8
Chemical Name
N-Formylglycine
Synonyms
FOR-GLY-OH;N-For-Gly-OH;Formylglycin;N-FORMYLGLYCIN;FORMYL-GLYCINE;N-FORMYLGLYCINE;N-α-Formylglycine;N-Formylglycine>Glycine, N-formyl-;N-FORMYLGLYCINE 98+%
CBNumber
CB0359737
Molecular Formula
C3H5NO3
Formula Weight
103.08
MOL File
2491-15-8.mol
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N-Formylglycine Property

Melting point:
149-151 °C
Boiling point:
193.26°C (rough estimate)
Density 
1.4873 (rough estimate)
refractive index 
1.4940 (estimate)
storage temp. 
2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
pka
pK1:3.43 (25°C)
color 
White
Water Solubility 
very faint turbidity
BRN 
1749108
CAS DataBase Reference
2491-15-8(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
MC0547000
HS Code 
29241990
Toxicity
LD50 unreported in rat: > 3gm/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
47723
Product name
N-Formylglycine
Purity
≥98.0%
Packaging
5g
Price
$369
Updated
2023/06/20
TCI Chemical
Product number
F0121
Product name
N-Formylglycine
Purity
>98.0%(T)
Packaging
5g
Price
$86
Updated
2025/07/31
TCI Chemical
Product number
F0121
Product name
N-Formylglycine
Purity
>98.0%(T)
Packaging
25g
Price
$273
Updated
2025/07/31
Usbiological
Product number
459117
Product name
N-Formylglycine
Packaging
1g
Price
$312
Updated
2021/12/16
TRC
Product number
F700445
Product name
N-Formylglycine
Packaging
1g
Price
$45
Updated
2021/12/16
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N-Formylglycine Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

N-Formylglycine is a simple dipeptide and a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.

Definition

ChEBI: An N-acylglycine resulting from the formal condensation of the amino group of glycine with formic acid.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

64-18-6

56-40-6

2491-15-8

The general procedure for the synthesis of 2-formamidoacetic acid from formic acid and glycine was as follows: formic acid (140 mL, 3.71 mol) was reacted with acetic anhydride (47 mL, 0.50 mol) with stirring for 1 hour at 45 °C. Subsequently, glycine (0.05 mol) was added to the reaction mixture and stirring was continued at room temperature for 24 hours. After completion of the reaction, the mixture was evaporated to dryness to afford the target product 2-formamidoacetic acid.

References

[1] Organic and Biomolecular Chemistry, 2015, vol. 14, # 1, p. 93 - 96
[2] Synthetic Communications, 1983, vol. 13, # 9, p. 745 - 752
[3] Organic Letters, 2018, vol. 20, # 18, p. 5877 - 5880
[4] Chemical Communications, 2012, vol. 48, # 31, p. 3775 - 3777
[5] Tetrahedron, 2013, vol. 69, # 43, p. 9161 - 9165

N-Formylglycine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-Formylglycine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Formylglycine 2491-15-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
N-Formylglycine 2491-15-8
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
200KG
Release date
2019-08-30

2491-15-8, N-FormylglycineRelated Search:


  • Formylglycin
  • N-FORMYLGLYCINE 98+%
  • 2-formamidoacetic acid
  • 2-formamidoethanoic acid
  • N-Formylglycine >=98.0%
  • <i>N</i>-Formylglycine
  • N-For-Gly-OH
  • N-ALPHA-FORMYL-GLYCINE
  • N-FORMYLGLYCIN
  • N-FORMYLGLYCINE
  • (FORMYLAMINO)ACETIC ACID
  • FORMYL-GLYCINE
  • FOR-GLY-OH
  • N-Formylglycine&gt
  • Glycine, N-formyl-
  • 2-formamidoaceticaci
  • N-Formylglycine USP/EP/BP
  • N-α-Formylglycine
  • N-Formylglycine , For-Gly-OH
  • N-Formylglycine, 10 mM in DMSO
  • 2491-15-8
  • C3H4NO3
  • C3H5NO3
  • HCONHCH2COOH
  • Amino Acid Derivatives
  • Peptide Synthesis
  • Specialty Synthesis
  • Amino Acid Derivatives
  • Glycine
  • Peptide Synthesis