ChemicalBook > CAS DataBase List > 2,4,5-TRIFLUOROBENZYL CHLORIDE

2,4,5-TRIFLUOROBENZYL CHLORIDE

Product Name
2,4,5-TRIFLUOROBENZYL CHLORIDE
CAS No.
243139-71-1
Chemical Name
2,4,5-TRIFLUOROBENZYL CHLORIDE
Synonyms
Sitagliptin Impurity 70;2,4,5-TRIFLUOROBENZYL CHORIDE;2,4,5-TRIFLUOROBENZYL CHLORIDE;alpha-Chloro-2,4,5-trifluorotoluene;Benzene, 1-(chloromethyl)-2,4,5-trifluoro-;Benzene, 1-(chloromethyl)-2,4,5-trifluoro- (9CI);1-(Chloromethyl)-2,4,5-trifluorobenzene, alpha-Chloro-2,4,5-trifluorotoluene
CBNumber
CB0361981
Molecular Formula
C7H4ClF3
Formula Weight
180.55
MOL File
243139-71-1.mol
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2,4,5-TRIFLUOROBENZYL CHLORIDE Property

Boiling point:
175℃
Density 
1,689 g/cm3
refractive index 
1.5050
Flash point:
65°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
clear liquid
color 
Colorless to Almost colorless
InChI
InChI=1S/C7H4ClF3/c8-3-4-1-6(10)7(11)2-5(4)9/h1-2H,3H2
InChIKey
JMXPOOVDUVHJRO-UHFFFAOYSA-N
SMILES
C1(CCl)=CC(F)=C(F)C=C1F
CAS DataBase Reference
243139-71-1(CAS DataBase Reference)
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Safety

Hazard Codes 
C,Xn
Risk Statements 
34-36/37/38-20/21/22
Safety Statements 
26-36/37/39-36
RIDADR 
3265
Hazard Note 
Corrosive
HazardClass 
8
PackingGroup 
II
HS Code 
2903998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H227Combustible liquid

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P390Absorb spillage to prevent material damage.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
T2889
Product name
2,4,5-Trifluorobenzyl Chloride
Purity
>98.0%(GC)
Packaging
1g
Price
$54
Updated
2024/03/01
TCI Chemical
Product number
T2889
Product name
2,4,5-Trifluorobenzyl Chloride
Purity
>98.0%(GC)
Packaging
5g
Price
$188
Updated
2024/03/01
Alfa Aesar
Product number
B20470
Product name
2,4,5-Trifluorobenzyl chloride, 97%
Packaging
1g
Price
$43.2
Updated
2023/06/20
Alfa Aesar
Product number
B20470
Product name
2,4,5-Trifluorobenzyl chloride, 97%
Packaging
5g
Price
$144
Updated
2021/12/16
TRC
Product number
T899188
Product name
2,4,5-Trifluorobenzyl Chloride
Packaging
50mg
Price
$45
Updated
2021/12/16
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2,4,5-TRIFLUOROBENZYL CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Colorless to Almost colorless clear liquid.

Uses

2,4,5-Trifluorobenzyl chloride is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor that decreases in glucagon to improve control of blood sugar used for the treatment of type 1 diabetes, 79% of the dose excreted in the urine.

Uses

2,4,5-Trifluorobenzyl chloride is a useful research chemical.

Synthesis

On the four-neck flask, install a stirrer, a thermometer, a chlorine gas pipe and a reflux condenser. The reflux condenser is connected to the HCl absorption system, and a light source is installed near the flask.Add 146.0g 2,4,5-trifluorotoluene and 3.0g azobisisobutyronitrile into the reaction flask, stir and heat, and when the temperature rises to 110°C, add dry chlorine gas, and Using GC tracking, after about 3h of chlorine gas, stop the halogenating agent chlorine gas, cool the reactant, wash it with water to neutrality, dry and distill under reduced pressure to obtain 2,4,5-trifluorobenzyl chloride.

2,4,5-TRIFLUOROBENZYL CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4,5-TRIFLUOROBENZYL CHLORIDE Suppliers

China 123 Europe 1 France 1 Germany 3 India 7 Japan 1 The Netherlands 1 Ukraine 1 United Kingdom 10 United States 20 Global 168
RR Scientific LLC
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View Lastest Price from 2,4,5-TRIFLUOROBENZYL CHLORIDE manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
2,4,5-TRIFLUOROBENZYL CHLORIDE 243139-71-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2022-11-17
Hebei Mojin Biotechnology Co., Ltd
Product
2,4,5-TRIFLUOROBENZYL CHLORIDE 243139-71-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-17
Zhuozhou Wenxi import and Export Co., Ltd
Product
2,4,5-TRIFLUOROBENZYL CHLORIDE 243139-71-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

243139-71-1, 2,4,5-TRIFLUOROBENZYL CHLORIDERelated Search:

Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin Impurity 34 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin impurity 5 Sitagliptin Impurity 77 Sitagliptin Impurity 28 2,2,2-TRIFLUORO-N'-(TRIFLUOROACETYL)ACETOHYDRAZIDE (S)-Sitagliptin Phosphate Sitagliptin DeaMino IMpurity 1 Sitagliptin Defuoro IMpurity 5 Sitagliptin Impurity 14 (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione 2,4,5-Trifluorophenylacetic acid

  • 2,4,5-TRIFLUOROBENZYL CHLORIDE
  • 2,4,5-TRIFLUOROBENZYL CHORIDE
  • Benzene, 1-(chloromethyl)-2,4,5-trifluoro- (9CI)
  • 1-(Chloromethyl)-2,4,5-trifluorobenzene, alpha-Chloro-2,4,5-trifluorotoluene
  • Sitagliptin Impurity 70
  • Benzene, 1-(chloromethyl)-2,4,5-trifluoro-
  • alpha-Chloro-2,4,5-trifluorotoluene
  • 243139-71-1
  • C7H4CIF3
  • Fluorine series
  • HALOMETYL
  • Miscellaneous