ChemicalBook > CAS DataBase List > DULCIN

DULCIN

Product Name
DULCIN
CAS No.
150-69-6
Chemical Name
DULCIN
Synonyms
1-(4-Ethoxyphenyl)urea;Dulcine;Valzin;Sucrol;DULCIN;Dulein;NSC 1839;Suesstoff;D-DULCINE;GLYCOSINE
CBNumber
CB0363233
Molecular Formula
C9H12N2O2
Formula Weight
180.2
MOL File
150-69-6.mol
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DULCIN Property

Melting point:
160-161℃
Boiling point:
313.03°C (rough estimate)
Density 
1.199
refractive index 
1.5373 (estimate)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Water Solubility 
1.21g/L(21 ºC)
λmax
289nm(EtOH)(lit.)
Merck 
14,3464
LogP
1.005 (est)
CAS DataBase Reference
150-69-6
IARC
3 (Vol. 12, Sup 7) 1987
EPA Substance Registry System
Dulcin (150-69-6)
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Safety

Hazard Codes 
Xi
RTECS 
YT2275000
Hazard Note 
Irritant
HS Code 
2924190090
Hazardous Substances Data
150-69-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1171
Product name
(4-Ethoxyphenyl)urea
Purity
>98.0%(HPLC)(N)
Packaging
200mg
Price
$67
Updated
2024/03/01
TCI Chemical
Product number
E1171
Product name
(4-Ethoxyphenyl)urea
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$198
Updated
2024/03/01
TRC
Product number
D720450
Product name
Dulcin
Packaging
1g
Price
$145
Updated
2021/12/16
SynQuest Laboratories
Product number
4653-1-X1
Product name
N-(4-Ethoxyphenyl)urea
Packaging
500mg
Price
$157
Updated
2021/12/16
AK Scientific
Product number
J11450
Product name
Dulcin
Packaging
100mg
Price
$80
Updated
2021/12/16
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DULCIN Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Dulcin is a non-nutritive sweetener. Dulcin is a sweet analgesic for use in medical procedures or treatments.

Definition

ChEBI: Dulcin is a member of ureas.

Production Methods

4-Ethoxyphenylurea, dulcin, is produced from the addition of potassium cyanate to p-phenetidine hydrochloride in aqueous solution at room temperature or from mixing urea and p-phenetidine hydrochloride to a mixture of hydrochloric acid and glacial acetic acid.

General Description

White crystals.

Air & Water Reactions

Partially decomposes on heating in water; hydrolyzes in 0.1 N acetic acid. Slightly water soluble .

Reactivity Profile

DULCIN is an example of an amide. Amides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Safety Profile

Human poison by ingestion. Moderately toxic experimentally by ingestion. Human systemic effects by ingestion: somnolence, hallucinations, distorted perceptions, and changes in motor activity. In adults 20 to 40 g produces dizziness, nausea, methemoglobinemia, cyanosis, and hypotension. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.

DULCIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from DULCIN manufacturers

Honest Joy Holdings Limited
Product
N-(4-Ethoxyphenyl)urea 150-69-6
Price
US $0.00/KG
Min. Order
1KG
Purity
97.8%
Supply Ability
100 tons
Release date
2022-02-08

150-69-6, DULCINRelated Search:

DULCIN Phenylurea Celiprolol Lufenuron NBP 584 1-(4-ETHOXYPHENYL)PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE talinolol dulcin saponin AURORA 4986 [4-(propan-2-yloxy)phenyl]urea AURORA 11864 AURORA 4981 AURORA 7437 N1-(2,6-DICHLORO-3-PYRIDYL)-2-([4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL]SULFANYL)ACETAMIDE AURORA 11901 AURORA 6612 SALOR-INT L308773-1EA AURORA 5617

  • Sucrol
  • Suesstoff
  • Urea, (4-ethoxyphenyl)-
  • Urea, (p-ethoxyphenyl)-
  • Valzin
  • Dulcin=4-Ethoxyphenylurea
  • p-ethoxyphyenylurea
  • PARA-ETHOXYPHENYLUREA
  • D-DULCINE
  • 4-Ureidophenetole
  • NSC 1839
  • Dulcin (sweetener)
  • p-Phenethyl carbamide
  • 4-Ureidophenetole, 4-(Carbamoylamino)phenetole
  • Urea,N-(4-ethoxyphenyl)-
  • ETHOXYPHENYL UREA
  • DULCIN
  • GLYCOSINE
  • AKOS B029772
  • N-(4-ETHOXYPHENYL)UREA
  • PHENETYL UREA
  • P-ETHOXYPHENYLUREA
  • P-PHENETOLECARBAMIDE
  • P-PHENETYLUREA
  • (p-ethoxyphenyl)-ure
  • 1-(4-Ethoxyphenyl)urea
  • 4-Ethoxyphenylurea
  • Dulcine
  • Dulein
  • NCI-C02073
  • p-Aethoxyphenylharnstoff
  • p-Ethoxyfenylmocovina
  • Phenethylcarbamid
  • Phenetolcarbamide
  • p-Phenethylurea
  • p-Phenetolcarbamid
  • p-Phenetolcarbamide
  • Dulcin/N-(4-Ethoxyphenyl)urea
  • 150-69-6
  • C2H5OC6H4NHCONH2
  • CH3CH2OC6H4NHCONH2
  • Amines
  • Aromatics