1-BROMO-2-BUTYNE
- Product Name
- 1-BROMO-2-BUTYNE
- CAS No.
- 3355-28-0
- Chemical Name
- 1-BROMO-2-BUTYNE
- Synonyms
- 1-Bromobut-2-yne;2-BUTYNYL BROMIDE;1-Bromobut-2-butyne;1-Brom-2-Butin;Linagliptin INT4;1-BROMO-2-BUTYNE;1-broMo -2-Ding Que;1-Bromobut-2-yne 95%;1-Bromo-2-butyne,98%;1-BROMO-2-BUTYNE 98%
- CBNumber
- CB0363349
- Molecular Formula
- C4H5Br
- Formula Weight
- 132.99
- MOL File
- 3355-28-0.mol
1-BROMO-2-BUTYNE Property
- Boiling point:
- 40-41 °C/20 mmHg (lit.)
- Density
- 1.519 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.508(lit.)
- Flash point:
- 97 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Miscible with acetonitrile.
- form
- Liquid
- Specific Gravity
- 1.519
- color
- Clear pale yellow-greenish
- BRN
- 605306
- InChIKey
- LNNXOEHOXSYWLD-UHFFFAOYSA-N
- CAS DataBase Reference
- 3355-28-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 427292
- Product name
- 1-Bromo-2-butyne
- Purity
- 99%
- Packaging
- 1g
- Price
- $31.2
- Updated
- 2024/03/01
- Product number
- 427292
- Product name
- 1-Bromo-2-butyne
- Purity
- 99%
- Packaging
- 5g
- Price
- $145
- Updated
- 2024/03/01
- Product number
- B2190
- Product name
- 1-Bromo-2-butyne
- Purity
- >96.0%(GC)
- Packaging
- 1g
- Price
- $38
- Updated
- 2024/03/01
- Product number
- B2190
- Product name
- 1-Bromo-2-butyne
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $104
- Updated
- 2024/03/01
- Product number
- L20134
- Product name
- 1-Bromo-2-butyne, 98%
- Packaging
- 5g
- Price
- $130
- Updated
- 2024/03/01
1-BROMO-2-BUTYNE Chemical Properties,Usage,Production
Chemical Properties
Clear pale yellow-greenish liquid
Uses
1-Bromo-2-butyne is used in the preparation of six to eight annulated ring compounds in reaction with indoles and pseudopterane (+/-)-Kallolide B, which is a marine natural product. Further, it acts as a precursor in the preparation of axially chiral teranyl compounds, alkylation of L-tryptophan methyl ester, 4-butynyloxybenzene sulfonyl chloride and mono-propargylated diene derivative. In addition to this, it is also used in the synthesis of isopropylbut-2-ynylamine, allenylcyclobutanol derivatives, allyl-[4-(but-2-ynyloxy)phenyl]sulfane, allenylindium and axially chiral teranyl compounds.
Preparation
1-bromo-2-butyne is obtained by reacting 2-butyn-1-ol and organic solvent, pyridine.First react bromoethane with metal magnesium in THF to prepare Grignard reagent, then add paraformaldehyde to Grignard reagent for Grignard reaction, separate and recover after Grignard reaction 2-butyn-1-ol, then mix 2-butyn-1-ol with organic solvent and pyridine, add phosphorus tribromide dropwise for bromination reaction, separate and recover the product after bromination reaction.
General Description
1-Bromo-2-butyne is a propargyl bromide derivative. It is one of the constitutional isomer of bromo butyne. Its Br-loss threshold photoionization breakdown diagram has been analyzed to derive dissociative photoionization thresholds to C4H5+ production. It participates in the preparation of linagliptin.
1-BROMO-2-BUTYNE Preparation Products And Raw materials
Raw materials
Preparation Products
1-BROMO-2-BUTYNE Suppliers
- Tel
- --
- Fax
- --
- brunschwig@brunschwig.nl
- Country
- The Netherlands
- ProdList
- 4996
- Advantage
- 67
View Lastest Price from 1-BROMO-2-BUTYNE manufacturers
- Product
- 1-BROMO-2-BUTYNE 3355-28-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-20
- Product
- 1-BROMO-2-BUTYNE 3355-28-0
- Price
- US $30.00-20.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20Tons
- Release date
- 2023-10-10
- Product
- 1-BROMO-2-BUTYNE 3355-28-0
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-22