Sulbactam sodium

ChemicalBook > CAS DataBase List > Sulbactam sodium

Product Name: Sulbactam sodium
CAS No.: 69388-84-7
Chemical Name: Sulbactam sodium
Synonyms: Sodium Sodium;Sulbatam Sodium;SODIUM SULBACTAM;Sterile Sulbactam sodium;(2S,5R);CP-45899-2;Shu ba sodium;sulbacyam sodium;SULBACTAM SODIUM;cp45899sodiumsalt
CBNumber: CB0370356
Molecular Formula: C8H12NNaO5S
Formula Weight: 257.24
MOL File: 69388-84-7.mol

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Sulbactam sodium Property

Melting point:: >230°C (dec.)
storage temp.: -20°C Freezer, Under Inert Atmosphere
solubility: Freely soluble in water, sparingly soluble in ethyl acetate, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute acids.
color: White
InChIKey: NKZMPZCWBSWAOX-IBTYICNHSA-M
CAS DataBase Reference: 69388-84-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 42/43
Safety Statements: 22-24-36/37-45-24/25
HS Code: 29349990
Toxicity: LD50 ivn-rat: 6500 mg/kg NKRZAZ 32(Suppl 4),97,84

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000529
Product name: Sulbactam sodium
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000529
Price: $220
Updated: 2024/03/01

TRC

Product number: S699185
Product name: SulbactamSodiumSalt
Packaging: 2g
Price: $180
Updated: 2021/12/16

TRC

Product number: S699185
Product name: SulbactamSodiumSalt
Packaging: 50mg
Price: $65
Updated: 2021/12/16

Axon Medchem

Product number: Axon2041
Product name: Sulbactamsodium-CP45899sodium
Purity: 98%
Packaging: 25mg
Price: $77
Updated: 2021/12/16

Apolloscientific

Product number: BIS0150
Product name: Sulbactam sodium
Packaging: 1g
Price: $95
Updated: 2021/12/16

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Sulbactam sodium Chemical Properties,Usage,Production

Description

Sulbactam sodium is a parenterally-active, β-lactamase inhibitor recently introduced as a 1: 1 combination product with cefoperazone. Like clavulanic acid, the first agent of this type to b e introduced, sulbactam enhances the effectiveness of β-lactam antibiotics against resistant strains.

Chemical Properties

White Solid

Originator

Pfizer (USA)

Uses

A semi-synthetic β-lactamase inhibitor. It is used in combination with β-lactam antibiotics as antibacterial.

Definition

ChEBI: Sulbactam sodium is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.

Manufacturing Process

Sulbactam sodium is semi-synthetic antibiotic of penicillinic group. Start material for it's synthesis is 6-aminopenicillanic acid. First 6-aminopenicillanic acid was isolated in 1957 year from benzylpenicilline as resalt of treating of it by penicillinaze. Benzylpenicilline is produced by microorganism of genus Streptomyces.
Further, 6-aminopenicillanic acid reacted with bromine, hydrochloric acid and NaNO2. As a result the 6,6-dibromopenicillanic acid was obtained.
6,6-Dibromopenicillanic acid was oxidized by KMnO4, to give 6,6-dibromo-1,1-The 6,6-dibromo-1,1-dioxopenicillanic acid in presence of Fe was converted to the 1,1-dioxopenicillanic acid (sulbactam acid). The sulbactam acid was treated by sodium 2-ethylhexanoate and crude sulbactam sodium was obtained.

brand name

SULPERAZONE

Therapeutic Function

Beta-lactamase inhibitor

General Description

Sulbactam was synthesized by Pfizer Research Laboratories in 1977 in the course of screening for β-lactamase inhibitors. It shows strong activity against penicillinase and moderate activity against cephalosporinase. Sulbactam itself shows activity against some gramnegative bacteria but no activity against most pathogenic bacteria. The use of sulbactam in combination with cefoperazone, which is partially hydrolyzed by penicillinase, is under study along with its use as an esterified complex with ampicillin (sultamicillin) for therapy of cefoperazone-ampicillin-resistant infections.

Safety Profile

Poison by intravenous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx

Sulbactam sodium Preparation Products And Raw materials

Raw materials

Sulbactam Sodium 2-ethylhexanoate

Preparation Products

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View Lastest Price from Sulbactam sodium manufacturers

Sinoway Industrial co., ltd.

Product: Sulbactam sodium 69388-84-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-04-03

Hebei Yime New Material Technology Co., Ltd.

Product: Sulbactam sodium 69388-84-7
Price: US $20.00/KG
Min. Order: 10KG
Purity: 99%
Supply Ability: 1000KG/day
Release date: 2024-02-28

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: Sulbactam sodium 69388-84-7
Price: US $5.00/kg
Min. Order: 1kg
Purity: 99.92%
Supply Ability: 50000tons
Release date: 2024-04-23

69388-84-7, Sulbactam sodiumRelated Search:

N,N-Dimethylformamide Sodium chloride Sodium benzoate ETHANE Dimethyl phthalate Dimethyl fumarate ISOHEPTANE Dimethyl sulfoxide Sodium formate Sodium gluconate Sulbactam Sodium 1-heptanesulfonate Sodium carbonate Sodium bicarbonate Sodium hydroxide Dimethyl sebacate Dimethyl ether Heptane

SULBACTAM SODIUM

SULBACTAM SODIUM SALT

sodium (2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

SODIUM SULBACTAM

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, sodium salt, (2S,5R)- (9CI)

Antibiotic medicine CAS 69388-84-7 veterinary sulbactam sodium

(2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3,2,0]heptane-2-carboxylic acid 4,4-dioxide sodium salt

Sulbatam Sodium

sodium (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

sulbacyam sodium

AMPICILLIN SODIUM AND SULBACTAM SODIUM 2:1

CP-45899-2

Penicillanic acid 4,4-dioxide sodium salt

Sterile Sulbactum Sodium Powder

SulbactaM SodiuM, USP

(2S,5R)

SulbactaM SodiuM API

3,3-dimethyl-7-oxo-4,4-dioxide-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, sodium salt (1:1)

sodium 3,3-dimethyl-4,4,7-trioxo-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Sulbactam sodium - CP 45899 sodium

4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,3,3-dimethyl-7-oxo-,4,4-d

cp45899sodiumsalt

penicillanicacid1,1-dioxidesodiumsalt

penicillanicaciddioxidesodiumsalt

penicillanicacidsulfonesodiumsalt

sodium1,1-dioxopenicillanate

sodiumpenicillanate1,1-dioxide

sodiumsalt,(2s-cis)-ioxid

Sulbactam sodium CRS

Sodium Sodium

Sulbactam sodium USP/EP/BP

Sterile Sulbactam sodium

Sulbactam sodiumQ: What is Sulbactam sodium Q: What is the CAS Number of Sulbactam sodium Q: What is the storage condition of Sulbactam sodium Q: What are the applications of Sulbactam sodium

Shu ba sodium

Natrium-(2S-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat-4,4-dioxid

Sulbactam Sodium (100 mg)

69388-84-7

C8H10NNaO5S

C8H10NO5SNa

25522

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69388-84-7