Butoxamine hydrochloride
- Product Name
- Butoxamine hydrochloride
- CAS No.
- 5696-15-1
- Chemical Name
- Butoxamine hydrochloride
- Synonyms
- BW-64-9;NSC-106565;AIDS-156055;BUTOXAMINE HCL;Butaxamine USP/EP/BP;Butaxamine hydrochloride;BUTOXAMINE HYDROCHLORIDE;Butoxamine hydrochloride USP/EP/BP;α-(1-[t-butylamino]ethyl)-2,5-dimethoxybenzyl alcohol;ALPHA-[1-(T-BUTYLAMINO)ETHYL]-2,5-DIMETHOXYBENZYL ALCOHOL HYDROCHLORIDE
- CBNumber
- CB0392437
- Molecular Formula
- C15H26ClNO3
- Formula Weight
- 303.82
- MOL File
- 5696-15-1.mol
Butoxamine hydrochloride Property
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B1385
- Product name
- Butoxamine hydrochloride
- Purity
- analytical standard, for drug analysis, mixture of diastereomers
- Packaging
- 50mg
- Price
- $186
- Updated
- 2024/03/01
- Product number
- B1385
- Product name
- Butoxamine hydrochloride
- Purity
- analytical standard, for drug analysis, mixture of diastereomers
- Packaging
- 500mg
- Price
- $876
- Updated
- 2022/05/15
- Product number
- B809510
- Product name
- Butoxamine hydrochloride
- Packaging
- 25mg
- Price
- $225
- Updated
- 2021/12/16
- Product number
- B809510
- Product name
- Butoxamine hydrochloride
- Packaging
- 50mg
- Price
- $445
- Updated
- 2021/12/16
Butoxamine hydrochloride Chemical Properties,Usage,Production
Originator
Butoxamine,SigmaAldrich
Uses
Antidiabetic; antihyperlipoproteinemic.
Uses
Butoxamine Hydrochloride is a beta-2 selective beta blocker. β2-adrenergic receptor(AR) antagonist; Antiarrhythmic;
Manufacturing Process
548.0 g (2 mol) of 2,5-dimethoxy-α-bromopropiophenone was dissolved in
500 ml of acetanitrile and 365.0 g (5 mol) of t-butylamine was added. The
solution was allowed to stand at room temperature for 64 h and was then
diluted with 2 L of anhydrous ether. The precipitated t-butylamine
hydrobromide was filtered off and washed with ether. The filtrate and
washings were concentrated in vacuo using a water-bath kept at 40°C. When
most of the solvent had been removed, the residual material was dissolve in
cold methanol and acidified with hydrochloric acid. The solution was then
taken down to dryness in vacuo on the steam bath and the 1-(2,5-
dimethoxyphenyl)-2-(t-butylamino)propiophenone was obtained, melting point
175-176°C (recrystallised from an ethanol ether mixture).
The bulk of the 1-(2,5-dimethoxyphenyl)-2-(t-butylamino)propiophenone was
dissolved in methanol and hydrogenated over platinum (Adams' catalyst).
After removal of the catalyst, the solvent was removed in vacuo and the
residual solid was dissolved in water and the solution was washed with ether.
The aqueous layer was basified (dilute sodium hydroxide solution) and the
base was taken into ether. After drying over anhydrous potassium carbonate,
the ether was evaporated and the base was distille at 0.3 mm pressure. So
the DL-erythro 1-(2,5-dimethoxyphenyl)-2-(t-butylamino)propanol, boiling
point 127-128°C was obtained.
Therapeutic Function
Oral hypoglycemic, Antihyperlipidemic
Butoxamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Butoxamine hydrochloride Suppliers
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