ChemicalBook > CAS DataBase List > ERYTHROSIN B

ERYTHROSIN B

Product Name
ERYTHROSIN B
CAS No.
16423-68-0
Chemical Name
ERYTHROSIN B
Synonyms
ebs;ERYTHROSINE;ERYTHROSINE B;TETRAIODOFLUORESCEIN;E127;45430;S 887;Ceplac;EOSIN J;1427red
CBNumber
CB0393696
Molecular Formula
C20H9I4NaO5
Formula Weight
859.89
MOL File
16423-68-0.mol
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ERYTHROSIN B Property

Melting point:
142~144℃
Density 
0.98
vapor pressure 
0Pa at 25℃
Flash point:
285℃
storage temp. 
room temp
solubility 
100g/l
Colour Index 
45430
pka
4.1(at 25℃)
form 
Fine Powder
color 
Deep red to brown
PH
6-7 (10g/l, H2O, 20℃)
PH Range
0(yellow)-3.6(red)
Water Solubility 
Soluble in water
λmax
525nm
Merck 
14,3693
BRN 
1443945
Stability:
Stable. Incompatible with strong oxidizing agents.
Biological Applications
Detecting gene expression,phosphoproteins,protease,stress biomarkers; treating age-related macular degeneration,arteriosclerosis,bone metabolic diseases,burns,cancer,diabetes,human immunodeficiency virus infection,obesity
Major Application
color filter, light emitting diodes, nanosensors, imaging materials, inks, paints, colored bubbles, detergents, cleaners, cosmetics, oral care agent, hair dyes, antiseptic, treatment of burns, diabetes, obesity, cancer, viral diseases, radio chemotheray, photodynamic therapy
InChIKey
RAGZEDHHTPQLAI-UHFFFAOYSA-L
LogP
-1.163 at 25℃
CAS DataBase Reference
16423-68-0
EPA Substance Registry System
Erythrosine B (16423-68-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
RTECS 
LM5950000
HS Code 
32129000
Hazardous Substances Data
16423-68-0(Hazardous Substances Data)
Toxicity
LD50 in male, female mice, male, female rats (g/kg): 0.40, 0.32, 0.34, 0.37 i.p.; 6.7, 6.9, 7.4, 6.8 orally (Butterworth); LD50 in mice, rats (mg/kg): 2558, 2891 orally (Yankell)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
45690
Product name
Erythrosin extra bluish
Purity
formicroscopy(Bact.,Hist.),adsorptionandfluorescentindicator
Packaging
10g
Price
$35
Updated
2024/03/01
Sigma-Aldrich
Product number
45690
Product name
Erythrosin extra bluish
Purity
formicroscopy(Bact.,Hist.),adsorptionandfluorescentindicator
Packaging
50g
Price
$124
Updated
2024/03/01
Sigma-Aldrich
Product number
198269
Product name
Erythrosin B
Purity
certified by the Biological Stain Commission, Dye content 90 %
Packaging
25g
Price
$69
Updated
2024/03/01
Sigma-Aldrich
Product number
1.15936
Product name
Erythrosine B (C.I. 45430)
Purity
formicroscopyCertistain?
Packaging
25g
Price
$101
Updated
2022/05/15
TCI Chemical
Product number
F0139
Product name
Food Red No. 3
Packaging
25g
Price
$118
Updated
2024/03/01
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ERYTHROSIN B Chemical Properties,Usage,Production

Description

FD & C Red No. 3 is principally the disodium salt of the monohydrate of 9(ocarboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H- xanthen-3-one.
The colorant is a brown powder that dissolves in water to give a solution red at neutrality, with a yellow-brown precipitate in acid, and with a red precipitate in base. When dissolved in concentrated sulfuric acid, it yields a brown-yellow solution that evolves iodine and a precipitate of the free acid when heated.
FD & C Red No. 3 is used in dietary supplements, confectionery products, dairy products, cherries, jellies, jams, dessert powders, canned fruit and vegetable products, fish products, condiment sauces and bakery goods.1 .

Chemical Properties

red to brown powder

Uses

antibacterial

Uses

Erythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine.

Uses

Erythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products.

Uses

Biological stain; color additive.

Definition

ChEBI: An organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid.

Preparation

fluorescent element (C.I. Acid Yellow 73, C.I. 45350) or ethanol in aqueous solution of the four iodine, then into sodium salt.

General Description

Erythrosin B (C.I. 45430)for microscopy Certistain?, is a dry dye for microscopy that is often used as a counterstain, vizualising proteins, connective tissues, fibers and keratin in sample material of human origin. Depending on user requirements and personal preferences, it can be used for the preparation of the commonly used aqueous or alcoholic Erythrosin B staining solutions. As the dye belongs to the portfolio of Certistain? dyes, it is chemically analyzed according to strict specifications before release (CE marked and IVD product) and a high staining quality, with reliable staining results is guaranteed. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Erythrosin B, also called as eosin B, is a xanthene dye. It belongs to the family of fluorescein dyes. Erythrosin B is an artificial food dye that induces hyperkinesis when swallowed by susceptible children. It plays a major role in inhibiting dopamine uptake and high affinity 3H-ouabain binding and ion transport in synaptosomes from rat caudate nucleus.

storage

Room temperature

Properties and Applications

blue light pink. Soluble in water is cherry red, no fluorescence. The strong sulfuric acid is palm in light yellow, diluted into palm yellow light precipitation. In water solution to join sodium hydroxide to create soluble red precipitate.

Standard Light Fastness Soaping Persperation Fastness Oxygen bleaching Fastness to seawater
Fading Stain Fading Stain Fading Stain
ISO 1 3 4 1 2-3

ERYTHROSIN B Preparation Products And Raw materials

Raw materials

Erythrosine aluminium lake Zinc chloride Ferric chloride Resorcinol Potassium dichromate Acid Red 51 Benzaldehyde Phthalic anhydride Fluorescein Aluminum sulfate 3-Aminophenol Aluminum hydroxide Sodium carbonate

Preparation Products

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ERYTHROSIN B Suppliers

Americas 1 Belgium 2 Canada 4 China 245 Europe 4 France 1 Germany 4 Hungary 1 India 74 Italy 1 Japan 4 Mexico 1 Norway 1 Poland 1 South Korea 1 Switzerland 3 United Kingdom 5 United States 48 USA 1 Global 402
TCI Chemicals (India) Pvt. Ltd.
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View Lastest Price from ERYTHROSIN B manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
ERYTHROSIN B 16423-68-0
Price
US $80.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-04-25
Hebei Shengyang Water Conservancy Engineering Co., Ltd.
Product
ERYTHROSIN B 16423-68-0
Price
US $18.00/kg
Min. Order
1kg
Purity
99.9
Supply Ability
5000
Release date
2024-05-10
Henan Fengda Chemical Co., Ltd
Product
ERYTHROSIN B 16423-68-0
Price
US $36.00-1.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-25

16423-68-0, ERYTHROSIN BRelated Search:

N,N'-Ethylenebis(stearamide) N,N'-ETHYLENEBISOLEAMIDE 4-Iodophenol 4-IODODIPHENYL ETHER 4-Iodoanisole Fluorescein Sodium 2,4,5,7-Erythrosi ERYTHROSIN B TETRAIODOPHENOLPHTHALEIN ROSE BENGAL ERYTHROSIN,ERYTHROSIN B LACTONE,ERYTHROSIN B,ERYTHROSIN B, SPIRIT SOLUBLE Erythrosin B extra,Erythrosin BB ERYTHROSIN Y C.I. NO. 45425,ERYTHROSIN YELLOWISH C.I. NO.45425,ERYTHROSIN Y,ERYTHROSIN YELLOWISH Erythrosine aluminium lake ERYTHROSIN B,ERYTHROSIN, DISODIUM SALT,ERYTHROSIN EXTRA BLUISH,ERYTHROSIN B, POLYMER BOUND,ERYTHROSIN BLUISH Acid Red 51 Xanthene Fluorescein

  • ERYTHROSIN B
  • ERYTHROSIN BLUISH
  • ERYTHROSIN B, POLYMER BOUND
  • ERYTHROSIN, DISODIUM SALT
  • ERYTHROSINE
  • ERYTHROSINE B
  • ERYTHROSINE B STAIN
  • ERYTHROSIN EXTRA BLUISH
  • EOSIN IODO
  • EOSIN J
  • DIANTHIN B
  • E127
  • CI NO 45430
  • FOOD RED NO 3
  • FD AND C RED NO 3
  • FD AND C RED 3
  • LAKE ERYTHROSINE
  • IODOEOSIN
  • IODOEOSINE SODIUM SALT
  • IODOEOSIN SODIUM SALT
  • IODEOSIN B
  • ACID RED 51 SODIUM SALT
  • 2',4',5',7'-TETRAIODOFLUORESCEIN DISODIUM SALT
  • 2',4',5',7'-TETRAIODO-FLUORESCEINE DISODIUM SALT
  • TETRAIODOFLUORESCEIN
  • TETRAIODOFLUORESCEIN SODIUM SALT
  • PYROSIN B
  • newpinkbluishgeigy
  • schultzno.887
  • Spiro[isobenzofuran-1(3H),9’-[9H]xanthen]-3-one,3’,6’-dihydroxy-2’,4’,5’,7’-tetraiodo-,disodiumsalt
  • Tetraiodofluorescein,sodiums
  • usacertredno.3
  • disodium 2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl)benzoate
  • 2',4',5',7'-Tetraiodo-3',6'-dihydroxy-spiro[3H-isobenzofuran-1,9'-xanthen]-3-one disodium salt
  • 2,4,5,7-Tetraiodo-3,6-dihydroxyxanthene-9-spiro-1'-3H-isobenzofuran-3'-one disodium salt
  • Erythrosin B, high purity biological stain
  • Erythrosine B disodium
  • Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4',5',7'-tetraiodo-, disodium salt
  • Tetraiodifluorescein, disodium salt
  • 1427red
  • 1671red
  • 2’,4’,5’,7’-tetraiodo-fluoresceidisodiumsalt
  • 2’,4’,5’,7’-tetraiodofluoroesceindisodiumsalt
  • 9-(o-carboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3h-xanthene-3-onedisodiumsa
  • aizenerythrosine
  • aizenfoodred3
  • c.i.773
  • c.i.acidred51
  • c.i.foodred14
  • calcociderythrosinen
  • canacerterythrosinebs
  • cervenkysela51
  • cervenpotravinarska14
  • cilefapinkb
  • d&credno.3
  • dolkwalerythrosine
  • dyefdandcredno.3
  • ebs